Search Results - "Habib, Raphaelle El"

Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti–HIV-1 drugs by Crespillo, Sara, Cámara-Artigas, Ana, Casares, Salvador, Morel, Bertrand, Cobos, Eva S., Mateo, Pedro L., Mouz, Nicolas, Martin, Christophe E., Roger, Marie G., Habib, Raphaelle El, Su, Bin, Moog, Christiane, Conejero-Lara, Francisco

“…During HIV-1 fusion to the host cell membrane, the N-terminal heptad repeat (NHR) and the C-terminal heptad repeat (CHR) of the envelope subunit gp41 become…”
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Safety and immunogenicity of an HIV subtype B and E prime-boost vaccine combination in HIV-negative Thai adults by Nitayaphan, Sorachai, Pitisuttithum, Punnee, Karnasuta, Chitraporn, Eamsila, Chirapa, de Souza, Mark, Morgan, Patricia, Polonis, Victoria, Benenson, Michael, VanCott, Tom, Ratto-Kim, Silvia, Kim, Jerome, Thapinta, Darawan, Garner, Robin, Bussaratid, Valai, Singharaj, Pricha, el Habib, Raphaelle, Gurunathan, Sanjay, Heyward, William, Birx, Deborah, McNeil, John, Brown, Arthur E.

“…ALVAC-HIV (vCP1521) and AIDSVAX B/E were evaluated in a phase 1/2 trial of human immunodeficiency virus (HIV)- negative Thai adults. Of 133 volunteers…”
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A Randomized, Partially Blinded Phase 2 Trial of Antiretroviral Therapy, HIV‐Specific Immunizations, and Interleukin‐2 Cycles to Promote Efficient Control of Viral Replication (ACTG A5024) by Kilby, J. Michael , Bucy, R. Pat , Mildvan, Donna , Fischl, Margaret , Santana‐Bagur, Jorge , Lennox, Jeff , Pilcher, Chris , Zolopa, Andrew , Lawrence, Jody , Pollard, Richard B. , Habib, Raphaelle El , Sahner, David , Fox, Lawrence , Aga, Evgenia , Bosch, Ronald J. 

“…Strategies to limit life‐long dependence on antiretroviral therapy (ART) are needed. We randomized 81 human immunodeficiency virus (HIV)–infected subjects to 4…”
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Impact of Therapeutic Immunization on HIV-1 Viremia after Discontinuation of Antiretroviral Therapy Initiated during Acute Infection by Kinloch–de Loes, Sabine, Hoen, Bruno, Smith, Don E., Autran, Brigitte, Lampe, Fiona C., Phillips, Andrew N., Goh, Li-Ean, Andersson, Jan, Tsoukas, Christos, Sonnerborg, Anders, Tambussi, Giuseppe, Girard, Pierre-Marie, Bloch, Mark, Battegay, Manuel, Carter, Nick, El Habib, Raphaelle, Theofan, Georgia, Cooper, David A., Perrin, Luc

“…BackgroundTreatment strategies that would induce durable virological control of human immunodeficiency virus (HIV)–1 in the absence of continued antiretroviral…”
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Interruption of antiretroviral therapy initiated during primary HIV-1 infection: impact of a therapeutic vaccination strategy combined with interleukin (IL)-2 compared with IL-2 alone in the ANRS 095 Randomized Study by Goujard, Cécile, Marcellin, Fabienne, Hendel-Chavez, Houria, Burgard, Marianne, Meiffrédy, Vincent, Venet, Alain, Rouzioux, Christine, Taoufik, Yacine, El Habib, Raphaëlle, Beumont-Mauviel, Maria, Aboulker, Jean-Pierre, Lévy, Yves, Delfraissy, Jean-François

“…HIV-specific T cell responses play a critical role in the control of infection. We evaluated the impact of immune-based interventions in patients first treated…”
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Safety and Immunogenicity of a Canarypox-Vectored Human Immunodeficiency Virus Type 1 Vaccine with or without gp120: A Phase 2 Study in Higher- and Lower-Risk Volunteers by Belshe, Robert B., Stevens, Cladd, Gorse, Geoffrey J., Buchbinder, Susan, Weinhold, Kent, Sheppard, Haynes, Stablein, Donald, Self, Steve, McNamara, James, Frey, Sharon, Flores, Jorge, Excler, Jean Louis, Klein, Michel, El Habib, Raphaelle, Duliege, Anne-Marie, Harro, Clayton, Corey, Lawrence, Keefer, Michael, Mulligan, Mark, Wright, Peter, Celum, Connie, Judson, Frank, Mayer, Kenneth, McKirnan, David, Marmor, Michael

“…Live attenuated viral vectors that express human immunodeficiency virus (HIV) antigens are being developed as potential vaccines to prevent HIV infection. The…”
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Therapeutic immunization with a human immunodeficiency virus (HIV) type 1-recombinant canarypox vaccine in chronically HIV-infected patients: The Vacciter Study (ANRS 094) by Tubiana, Roland, Carcelain, Guislaine, Vray, Muriel, Gourlain, Karine, Dalban, Cécile, Chermak, Aziza, Rabian, Claire, Vittecoq, Daniel, Simon, Anne, Bouvet, Elisabeth, Habib, Raphaelle El, Costagliola, Dominique, Calvez, Vincent, Autran, Brigitte, Katlama, Christine

“…This open single-arm study evaluated whether the administration of an HIV-recombinant canarypox vaccine (vCP1433) in highly active antiretroviral therapy…”
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CCR5 or CXCR4 use influences the relationship between CD4 cell depletion, NKp44L expression and NK cytotoxicity in SHIV-infected macaques by VIEILLARD, Vincent, EL HABIB, Raphaelle, LE GRAND, Roger, DEBRE, Patrice, BROCHARD, Patricia, DELACHE, Benoit, FAUSTHER BOVENDO, Hugues, CALVO, Julien, MORIN, Julie, PICQ, Isabelle, MARTINON, Frédéric, VASLIN, Bruno

“…HIV-1 infection is characterized by a progressive decline of CD4 cell count, the underlying mechanisms of which are still debated. We recently found that…”
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Assessment of mucosal immunity to HIV-1 by Jespers, Vicky, Harandi, Ali M, Hinkula, Jorma, Medaglini, Donata, Le Grand, Roger, Stahl-Hennig, Christiane, Bogers, Willy, El Habib, Raphaelle, Wegmann, Frank, Fraser, Carol, Cranage, Martin, Shattock, Robin J, Spetz, Anna-Lena

“…A key gap in the development and evaluation of HIV-1 vaccines is insufficient knowledge with regard to sampling techniques and assessment of mucosal immune…”
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Safety and Immunogenicity of ALVAC vCP1452 and Recombinant gp160 in Newly Human Immunodeficiency Virus Type 1-Infected Patients Treated with Prolonged Highly Active Antiretroviral Therapy by Xia Jin, Murugappan Ramanathan, Jr, Shady Barsoum, Geoffrey R. Deschenes, Lei Ba, James Binley, Daryl Schiller, Daniel E. Bauer, Donald C. Chen, Arlene Hurley, Lucette Gebuhrer, Raphaelle El Habib, Pierre Caudrelier, Michel Klein, Linqi Zhang, David D. Ho, Martin Markowitz

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Polymorphisms in HLA Class I Genes Associated with both Favorable Prognosis of Human Immunodeficiency Virus (HIV) Type 1 Infection and Positive Cytotoxic T-Lymphocyte Responses to ALVAC-HIV Recombinant Canarypox Vaccines by Kaslow, R A, Rivers, C, Tang, J, Bender, T J, Goepfert, P A, El Habib, R, Weinhold, K, Mulligan, M J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Comparison of Systemic and Mucosal Delivery of 2 Canarypox Virus Vaccines Expressing either HIV-1 Genes or the Gene for Rabies Virus G Protein by Wright, Peter F., Mestecky, Jiri, McElrath, M. Juliana, Keefer, Michael C., Gorse, Geoffrey J., Goepfert, Paul A., Moldoveanu, Zina, Schwartz, David, Spearman, Paul W., El Habib, Raphaelle, Spring, Michele D., Zhu, Yuwei, Smith, Carol, Flores, Jorge, Weinhold, Kent J.

“…Background. Since the primary routes of human immunodeficiency type 1 (HIV-1) infection are across mucosal barriers, a randomized trial of canarypox…”
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A Phase 1/2 Comparative Vaccine Trial of the Safety and Immunogenicity of a CRF01_AE (Subtype E) Candidate Vaccine: ALVAC-HIV (vCP1521) Prime With Oligomeric gp160 (92TH023/LAI-DID) or Bivalent gp120 (CM235/SF2) Boost by Thongcharoen, Prasert, Suriyanon, Vinai, Paris, Robert M, Khamboonruang, Chirasak, de Souza, Mark S, Ratto-Kim, Silvia, Karnasuta, Chitraporn, Polonis, Victoria R, Baglyos, Lynn, Habib, Raphaelle El, Gurunathan, Sanjay, Barnett, Susan, Brown, Arthur E, Birx, Deborah L, McNeil, John G, Kim, Jerome H

“…BACKGROUND:The development of an effective HIV-1 vaccine is critical to control the pandemic. A prime-boost HIV-1 vaccine trial assessing safety and…”
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Comparison Between Env-Specific T-Cell Epitopic Responses in HIV-1-Uninfected Adults Immunized with Combination of ALVAC-HIV(vCP205) Plus or Minus rgp160MN/LAI-2 and HIV-1-Infected Adults by Ratto-Kim, Silvia, Loomis-Price, Lawrence D, Aronson, Naomi, Grimes, Janelle, Hill, Cristin, Williams, Chevelle, Habib, Raphaelle El, Birx, Deborah L, Kim, Jerome H

“…In this study, we investigated the CD4 T-helper response induced by ALVAC-HIV(vCP205) ± rgp160MN/LAI-2 using a series of 15 overlapping amino acid peptides…”
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The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope by de Souza, Mark S, Ratto-Kim, Silvia, Chuenarom, Weerawan, Schuetz, Alexandra, Chantakulkij, Somsak, Nuntapinit, Bessara, Valencia-Micolta, Anais, Thelian, Doris, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Paris, Robert M, Kaewkungwal, Jaranit, Michael, Nelson L, Rerks-Ngarm, Supachai, Mathieson, Bonnie, Marovich, Mary, Currier, Jeffrey R, Kim, Jerome H

“…The Thai HIV phase III prime/boost vaccine trial (RV144) using ALVAC-HIV (vCP1521) and AIDSVAX B/E was, to our knowledge, the first to demonstrate acquisition…”
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Molecular and Physicochemical Factors Governing Solubility of the HIV gp41 Ectodomain by Manssour-Triedo, Fadia, Crespillo, Sara, Morel, Bertrand, Casares, Salvador, Mateo, Pedro L., Notka, Frank, Roger, Marie G., Mouz, Nicolas, El-Habib, Raphaelle, Conejero-Lara, Francisco

“…The HIV gp41 ectodomain (e-gp41) is an attractive target for the development of vaccines and drugs against HIV because of its crucial role in viral fusion to…”
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Safety and Immunogenicity of a Randomized Phase 1 Prime-Boost Trial With ALVAC-HIV (vCP205) and Oligomeric Glycoprotein 160 From HIV-1 Strains MN and LAI-2 Adjuvanted in Alum or Polyphosphazene by O'Connell, Robert J., Excler, Jean-Louis, Polonis, Victoria R., Ratto-Kim, Silvia, Cox, Josephine, Jagodzinski, Linda L., Liu, Michelle, Wieczorek, Lindsay, McNeil, John G., El-Habib, Raphaelle, Michael, Nelson L., Gilliam, Bruce L., Paris, Robert, VanCott, Thomas C., Tomaras, Georgia D., Birx, Deborah L., Robb, Merlin L., Kim, Jerome H.

“…Background. Prime-boost regimens comprising ALVAC-HIV (prime) and human immunodeficiency virus type 1 (HIV) Env (boost) induce HIV-specific neutralizing…”
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Correlation between arachidonic acid oxygenation and luminol-induced chemiluminescence in neutrophils: Inhibition by diethyldithiocarbamate by Chabannes, Bernard, Perraut, Catherine, Habib, Raphaelle El, Moliere, Patrick, Pacheco, Yves, Lagarde, Michel

“…Neutrophils from allergic subjects were hypersensitive to stimulation by low calcium ionophore concentration (0.15 μM), resulting in an increased formation of…”
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Greater viral rebound and reduced time to resume antiretroviral therapy after therapeutic immunization with the ALVAC-HIV vaccine (vCP1452) by Autran, Brigitte, Murphy, Robert L, Costagliola, Dominique, Tubiana, Roland, Clotet, Bonaventura, Gatell, Jose, Staszewski, Schlomo, Wincker, Norma, Assoumou, Lambert, El-Habib, Raphaelle, Calvez, Vincent, Walker, Bruce, Katlama, Christine

“…Evaluate immunogenicity and clinical efficacy of two immunization strategies with the ALVAC-HIV-recombinant canarypox vaccine (vCP1452) in treated HIV-infected…”
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Immunological parameters during treatment with ditiocarb (Imuthiol) by Vanham, G L, Kestens, L, Van Hoof, J, Penne, G, Colebunders, R, Goilav, C, Vandenbruaene, M, el Habib, R, Gigase, P

“…To examine the effect of ditiocarb (DTC) treatment on immunological parameters of HIV infection. Immunophenotyping included CD4+ T-cell counting and the…”
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