Search Results - "Habib, Monica"
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Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability
Published in Journal of medicinal chemistry (23-11-2023)“…EPI-X4, a natural peptide CXCR4 antagonist, shows potential for treating inflammation and cancer, but its short plasma stability limits its clinical…”
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An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation
Published in Acta pharmaceutica Sinica. B (01-09-2021)“…Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin,…”
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Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents
Published in Archiv der Pharmazie (Weinheim) (01-12-2015)“…Eighteen new 5‐benzylidene‐3‐(4‐arylpiperazin‐1‐ylmethyl)‐2‐thioxo‐imidazolidin‐4‐ones were designed as hybrid structures from previously reported…”
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Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stability
Published in Journal of controlled release (01-09-2024)“…Dysregulation of the CXCL12/CXCR4 axis is implicated in autoimmune, inflammatory, and oncogenic diseases, positioning CXCR4 as a pivotal therapeutic target. We…”
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Hit evaluation of an α-helical peptide: Ala-scan, truncation and sidechain-to-sidechain macrocyclization of an RNA polymerase Inhibitor
Published in Biological chemistry (25-02-2019)“…RNA polymerase (RNAP) remains a relatively underexplored target with only rifampicin and fidaxomicin in clinical use. Hence, the concurrent rise in bacterial…”
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Comparison Between Handgrip Dynamometry and Manual Muscle Testing Performed by Registered Dietitians in Measuring Muscle Strength and Function of Hospitalized Patients
Published in JPEN. Journal of parenteral and enteral nutrition (01-09-2016)“…Background: The Academy of Nutrition and Dietetics and American Society the Parenteral and Enteral Nutrition (ASPEN) Consensus Statement recommends a…”
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The Association Between Home Parenteral Nutrition and Patients With FAP-Associated Intra-Abdominal Desmoids: A Retrospective Study
Published in JPEN. Journal of parenteral and enteral nutrition (01-09-2013)“…Background: Intra-abdominal desmoid tumors (IADTs) are a common complication of familial adenomatous polyposis (FAP). Treatment is not standardized for…”
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The Association Between Home Parenteral Nutrition and Patients With FAP‐Associated Intra‐Abdominal Desmoids
Published in JPEN. Journal of parenteral and enteral nutrition (01-09-2013)“…Background: Intra‐abdominal desmoid tumors (IADTs) are a common complication of familial adenomatous polyposis (FAP). Treatment is not standardized for…”
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