Search Results - "Haberzettl, Petra"

Circadian toxicity of environmental pollution. Inhalation of polluted air to give a precedent by Haberzettl, Petra

“…Exposures to environmental stressors that derive from pollution (e.g. air, light) or lifestyle choices (e.g. diet, activity, 24-hour-×-7-day) are associated…”
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Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response by Haberzettl, Petra, Hill, Bradford G

“…Excessive production of unsaturated aldehydes from oxidized lipoproteins and membrane lipids is a characteristic feature of cardiovascular disease. Our…”
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Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein by Conklin, Daniel J., Haberzettl, Petra, Jagatheesan, Ganapathy, Kong, Maiying, Hoyle, Gary W.

“…Acrolein is a highly toxic, volatile, unsaturated aldehyde generated during incomplete combustion as in tobacco smoke and indoor fires. Because the transient…”
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Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells by Hill, Bradford G, Haberzettl, Petra, Ahmed, Yonis, Srivastava, Sanjay, Bhatnagar, Aruni

“…Proteins modified by aldehydes generated from oxidized lipids accumulate in cells during oxidative stress and are commonly detected in diseased or aged tissue…”
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Exposure to Ambient Air Fine Particulate Matter Prevents VEGF-Induced Mobilization of Endothelial Progenitor Cells from the Bone Marrow by HABERZETTL, Petra, LEE, Jongmin, DUGGINENI, Dheeraj, MCCRACKEN, James, BOLANOWSKI, Duane, O'TOOLE, Timothy E, BHATNAGAR, Aruni, CONKLIN, Daniel J

“…Exposure to ambient fine particulate matter air pollution (PM(2.5); < 2.5 µm in aerodynamic diameter) induces endothelial dysfunction and increases the risk…”
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Episodic Exposure to Fine Particulate Air Pollution Decreases Circulating Levels of Endothelial Progenitor Cells by OʼToole, Timothy E, Hellmann, Jason, Wheat, Laura, Haberzettl, Petra, Lee, Jongmin, Conklin, Daniel J, Bhatnagar, Aruni, Pope, C. Arden

“…RATIONALE:Acute and chronic exposures to airborne particulate matter (PM) have been linked in epidemiological studies to a wide spectrum of cardiovascular…”
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Lipid Peroxidation Product 4-Hydroxy-trans-2-nonenal Causes Endothelial Activation by Inducing Endoplasmic Reticulum Stress by Vladykovskaya, Elena, Sithu, Srinivas D., Haberzettl, Petra, Wickramasinghe, Nalinie S., Merchant, Michael L., Hill, Bradford G., McCracken, James, Agarwal, Abhinav, Dougherty, Susan, Gordon, Sharon A., Schuschke, Dale A., Barski, Oleg A., O'Toole, Timothy, D'Souza, Stanley E., Bhatnagar, Aruni, Srivastava, Sanjay

“…Lipid peroxidation products, such as 4-hydroxy-trans-2-nonenal (HNE), cause endothelial activation, and they increase the adhesion of the endothelium to…”
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Carnosine Supplementation Mitigates the Deleterious Effects of Particulate Matter Exposure in Mice by Abplanalp, Wesley, Haberzettl, Petra, Bhatnagar, Aruni, Conklin, Daniel J, O'Toole, Timothy E

“…Background Exposure to fine airborne particulate matter ( PM ) induces quantitative and qualitative defects in bone marrow-derived endothelial progenitor cells…”
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Fine particulate matter air pollution and aortic perivascular adipose tissue: Oxidative stress, leptin, and vascular dysfunction by Haberzettl, Petra, Jin, Lexiao, Riggs, Daniel W., Zhao, Jingjing, O’Toole, Timothy E., Conklin, Daniel J.

“…Exposure to fine particulate matter (PM2.5) air pollution increases blood pressure, induces vascular inflammation and dysfunction, and augments atherosclerosis…”
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Aldose Reductase (AR) Mediates and Perivascular Adipose Tissue (PVAT) Modulates Endothelial Dysfunction of Short-Term High-Fat Diet Feeding in Mice by Conklin, Daniel J, Haberzettl, Petra, MacKinlay, Kenneth G, Murphy, Daniel, Jin, Lexiao, Yuan, Fangping, Srivastava, Sanjay, Bhatnagar, Aruni

“…Increased adiposity of both visceral and perivascular adipose tissue (PVAT) depots is associated with an increased risk of diabetes and cardiovascular disease…”
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Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms by Scherbart, Agnes M, Langer, Julia, Bushmelev, Alexey, van Berlo, Damien, Haberzettl, Petra, van Schooten, Frederik-Jan, Schmidt, Annette M, Rose, Christine R, Schins, Roel P F, Albrecht, Catrin

“…Inhalation of (nano)particles may lead to pulmonary inflammation. However, the precise mechanisms of particle uptake and generation of inflammatory mediators…”
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Arsenic exacerbates atherosclerotic lesion formation and inflammation in ApoE-/- mice by Srivastava, Sanjay, Vladykovskaya, Elena N., Haberzettl, Petra, Sithu, Srinivas D., D'Souza, Stanley E., States, J. Christopher

“…Exposure to arsenic-contaminated water has been shown to be associated with cardiovascular disease, especially atherosclerosis. We examined the effect of…”
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Increased sensitivity of glutathione S-transferase P-null mice to cyclophosphamide-induced urinary bladder toxicity by Conklin, Daniel J, Haberzettl, Petra, Lesgards, Jean-Francois, Prough, Russell A, Srivastava, Sanjay, Bhatnagar, Aruni

“…Hemorrhagic cystitis and diffuse inflammation of the bladder, common side effects of cyclophosphamide (CY) treatment, have been linked to the generation of…”
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Exposure to acrolein by inhalation causes platelet activation by Sithu, Srinivas D., Srivastava, Sanjay, Siddiqui, Maqsood A., Vladykovskaya, Elena, Riggs, Daniel W., Conklin, Daniel J., Haberzettl, Petra, O'Toole, Timothy E., Bhatnagar, Aruni, D'Souza, Stanley E.

“…Acrolein is a common air pollutant that is present in high concentrations in wood, cotton, and tobacco smoke, automobile exhaust and industrial waste and…”
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Reply to Della Guardia and Shin by Haberzettl, Petra

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The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung by Albrecht, Catrin, Knaapen, Ad M, Becker, Andrea, Höhr, Doris, Haberzettl, Petra, van Schooten, Frederik J, Borm, Paul J A, Schins, Roel P F

“…Persistent inflammation and associated excessive oxidative stress have been crucially implicated in quartz-induced pulmonary diseases, including fibrosis and…”
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Actin plays a crucial role in the phagocytosis and biological response to respirable quartz particles in macrophages by HABERZETTL, Petra, DUFFIN, Rodger, KRÄMER, Ursula, HÖHR, Doris, SCHINS, Roel P. F, BORM, Paul J. A, ALBRECHT, Catrin

“…The uptake of respirable quartz particles by alveolar macrophages (AM) is believed to cause an inflammatory response, which is discussed as a crucial step in…”
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Surface-Dependent Quartz Uptake by Macrophages: Potential Role in Pulmonary Inflammation and Lung Clearance by Albrecht, Catrin, Höhr, Doris, Haberzettl, Petra, Becker, Andrea, Borm, Paul J. A., Schins, Roel P. F.

“…Inhalation of quartz particles is associated with a variety of adverse lung effects. Since particle surface is considered to be crucial for particle…”
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Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress by Haberzettl, Petra, O'Toole, Timothy E, Bhatnagar, Aruni, Conklin, Daniel J

“…Epidemiological evidence suggests that exposure to ambient air fine particulate matter (PM2.5) increases the risk of developing type 2 diabetes and…”
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Fine particulate matter (PM 2.5 ) inhalation-induced alterations in the plasma lipidome as promoters of vascular inflammation and insulin resistance by Hill, Bradford G, Rood, Benjamin, Ribble, Amanda, Haberzettl, Petra

“…Fine particulate matter (PM ) air pollution exposure increases the risk of developing cardiovascular disease (CVD). Although the precise mechanisms by which…”
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