Search Results - "Haber, D. A"

Meridional Circulation Variability from Large-Aperture Ring-Diagram Analysis of Global Oscillation Network Group and Michelson Doppler Imager Data by González Hernández, I, Komm, R, Hill, F, Howe, R, Corbard, T, Haber, D. A

“…Ring-diagram analysis, a local helioseismology technique, has proven to be very useful for studying solar subsurface velocity flows down to a depth of about…”
Get full text

The Linear Sensitivity of Helioseismic Ring Diagrams to Local Flows by Birch, A. C, Gizon, L, Hindman, B. W, Haber, D. A

“…Ring-diagram analysis is a technique of local helioseismology used to infer plasma flows in the solar convection zone which generates intermediate data…”
Get full text

Loss of Imprinting of Insulin-Like Growth Factor-II (IGF2) Gene in Distinguishing Specific Biologic Subtypes of Wilms Tumor by Ravenel, Jason D., Broman, Karl W., Perlman, Elizabeth J., Niemitz, Emily L., Jayawardena, Tilanthi M., Bell, Daphne W., Haber, Daniel A., Uejima, Hiroshi, Feinberg, Andrew P.

“…Background: Loss of imprinting (LOI) of the insulin-like growth factor-II (IGF2) gene, an epigenetic alteration associated with expression of the normally…”
Get full text

Heterozygous Germ Line hCHK2 Mutations in Li-Fraumeni Syndrome by Bell, Daphne W., Varley, Jennifer M., Szydlo, Tara E., Kang, Deborah H., Doke C. R. Wahrer, Shannon, Kristen E., Lubratovich, Marcie, Verselis, Sigitas J., Isselbacher, Kurt J., Fraumeni, Joseph F., Birch, Jillian M., Li, Frederick P., Garber, Judy E., Haber, Daniel A.

“…The hCHK2 gene encodes the human homolog of the yeast Cds1 and Rad53 G$_2$ checkpoint kinases, whose activation in response to DNA damage prevents cellular…”
Get full text

In vitro phosphorylation of BRCA2 by the checkpoint kinase CHEK2 by Kim, S, Mohapatra, G, Haber, D A

“…Germline mutations in both BRCA2 and CHEK2 are associated with an increased risk for male breast cancer. To search for potential interactions between the…”
Get full text

WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis by Englert, C., Hou, X., Maheswaran, S., Bennett, P., Ngwu, C., Re, G. G., Garvin, A. J., Rosner, M. R., Haber, D. A.

“…The Wilms tumor suppressor gene WT1 encodes a developmentally regulated transcription factor that is mutated in a subset of embryonal tumors. To test its…”
Get full text

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase by COUNTER, C. M, MEYERSON, M, EATON, E. N, ELLISEN, L. W, CADDLE, S. D, HABER, D. A, WEINBERG, R. A

“…The expression of telomerase, the enzyme that synthesizes telomeric DNA de novo, is suppressed in normal somatic human cells but is reactivated during…”
Get full text

Hemophagocytic lymphohistiocytosis due to germline mutations in SH2D1A, the X-linked lymphoproliferative disease gene by ARICO, Maurizio, IMASHUKU, Shinsaku, CLEMENTI, Rita, HIBI, Shigeyoshi, TERAMURA, Tomoko, DANESINO, Cesare, HABER, Daniel A, NICHOLS, Kim E

“…The hemophagocytic lymphohistiocytoses (HLH) comprise a heterogeneous group of disorders characterized by dysregulated activation of T cells and macrophages…”
Get full text

Alternative Splicing and Genomic Structure of the Wilms Tumor Gene WT1 by Haber, Daniel A., Sohn, Robert L., Buckler, Alan J., Pelletier, Jerry, Call, Katherine M., Housman, David E.

“…The chromosome 11p13 Wilms tumor susceptibility gene WT1 appears to play a crucial role in regulating the proliferation and differentiation of nephroblasts and…”
Get full text

Expression of the Wilms' tumor gene WT1 in the murine urogenital system by PELLETIER, J, SCHALLING, M, BUCKLER, A. J, ROGERS, A, HABER, D. A, HOUSMAN, D

“…The Wilms' tumor gene WT1 is a recessive oncogene that encodes a putative transcription factor implicated in nephrogenesis during kidney development. In this…”
Get full text

The Global Context of Solar Activity During the Whole Heliosphere Interval Campaign by Webb, D. F., Cremades, H., Sterling, A. C., Mandrini, C. H., Dasso, S., Gibson, S. E., Haber, D. A., Komm, R. W., Petrie, G. J. D., McIntosh, P. S., Welsch, B. T., Plunkett, S. P.

“…The Whole Heliosphere Interval (WHI) was an international observing and modeling effort to characterize the 3-D interconnected “heliophysical” system during…”
Get full text

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis by Maheswaran, S, Englert, C, Bennett, P, Heinrich, G, Haber, D A

“…The Wilms' tumor-suppressor gene product WT1 coimmunoprecipitates with p53 from baby rat kidney (BRK) cells and Wilms' tumor specimens, and expression of WT1…”
Get full text

Heterozygous ATM mutations do not contribute to early onset of breast cancer by FitzGerald, Michael G, Bean, James M, Hegde, Sanjay R, Unsal, Hilal, MacDonald, Deborah J, Harkin, D. Paul, Finkelstein, Dianne M, Isselbacher, Kurt J, Haber, Daniel A

“…Ataxia telangiectasia (AT) is a recessive syndrome, including cerebellar degeneration, immunologic defects and cancer predisposition, attributed to mutations…”
Get full text

Large-Scale Zonal Flows Near the Solar Surface: A Comparison of Results from Local and Global Helioseismology with Direct Doppler Measurements by Howe, R., Komm, R., Hill, F., Ulrich, R., Haber, D. A., Hindman, B. W., Schou, J., Thompson, M. J.

“…Migrating bands of weak, zonal flow, associated with the activity bands in the solar cycle, have been observed at the solar surface for some time. More…”
Get full text

Exon Amplification: A Strategy to Isolate Mammalian Genes Based on RNA Splicing by BUCKLER, A. J, CHANG, D. D, GRAW, S. L, BROOK, J. D, HABER, D. A, SHARP, P. A, HOUSMAN, D. E

“…We have developed a method, exon amplification, for fast and efficient isolation of coding sequences from complex mammalian genomic DNA. This method is based…”
Get full text

Differential Rotation and Dynamics of the Solar Interior by Thompson, M. J., Toomre, J., Anderson, E. R., Antia, H. M., Berthomieu, G., Burtonclay, D., Chitre, S. M., Christensen-Dalsgaard, J., Corbard, T., DeRosa, M., Genovese, C. R., Gough, D. O., Haber, D. A., Harvey, J. W., Hill, F., Howe, R., Korzennik, S. G., Kosovichev, A. G., Leibacher, J. W., Pijpers, F. P., Provost, J., Rhodes, E. J., Schou, J., Sekii, T., Stark, P. B., Wilson, P. R.

“…Splitting of the sun's global oscillation frequencies by large-scale flows can be used to investigate how rotation varies with radius and latitude within the…”
Get full text

Activity-related Changes in Local Solar Acoustic Mode Parameters from Michelson Doppler Imager and Global Oscillations Network Group by Howe, R, Komm, R. W, Hill, F, Haber, D. A, Hindman, B. W

“…We use the ring-diagram technique of local helioseismology to study the amplitude and line width of high-degree solar acoustic modes from 474 days of data from…”
Get full text

Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families by Tonin, P, Weber, B, Offit, K, Couch, F, Rebbeck, T.R, Neuhausen, S, Godwin, A.K, Daly, M, Wagner-Costalos, J, Berman, D, Grana, G, Fox, E, Kane, M.F, Kolodner, R.D, Krainer, M, Haber, D.A, Struewing, J.P, Warner, E, Rosen, B, Lerman, C, Peshkin, B, Norton, L, Serova, O, Foulkes, W.D, Lynch, H.T, Lenoir, G.M, Narod, S.A, Garber, J.E

“…Germline mutations in the breast cancer susceptibility genes BRCA1 and BRCA2 account for the majority of families with hereditary breast cancer. Among women…”
Get full text

Differential Contributions of BRCA1 and BRCA2 to Early-Onset Breast Cancer by Krainer, Michael, Silva-Arrieta, Sandra, FitzGerald, Michael G, Shimada, Akira, Ishioka, Chikashi, Kanamaru, Ryunosuke, MacDonald, Deborah J, Unsal, Hilal, Finkelstein, Dianne M, Bowcock, Anne, Isselbacher, Kurt J, Haber, Daniel A

“…Studies of large families many of whose members have cancer have led to the identification of two genes, BRCA1 and BRCA2, that, when mutated, predispose family…”
Get full text

The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour by Lee, Sean Bong, Kolquist, Kathryn Ann, Nichols, Kim, Englert, Christoph, Maheswaran, Shyamala, Ladanyi, Marc, Gerald, William L, Haber, Daniel A

“…Chromosomal translocations resulting in chimaeric transcription factors underlie specific malignancies, but few authentic target genes regulated by these…”
Get full text