Search Results - "Habela, Christa"

Modeling synaptogenesis in schizophrenia and autism using human iPSC derived neurons by Habela, Christa W., Song, Hongjun, Ming, Guo-li

“…Schizophrenia (SCZ) and autism spectrum disorder (ASD) are genetically and phenotypically complex disorders of neural development. Human genetic studies, as…”
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Phase-amplitude coupling detection and analysis of human 2-dimensional neural cultures in multi-well microelectrode array in vitro by Salimpour, Yousef, Anderson, William S., Dastgheyb, Raha, Liu, Shiyu, Ming, Guo-li, Song, Hongjun, Maragakis, Nicholas J., Habela, Christa W.

“…Human induced pluripotent stem cell (hiPSC)- derived neurons offer the possibility of studying human-specific neuronal behaviors in physiologic and pathologic…”
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Genetic Testing to Inform Epilepsy Treatment Management From an International Study of Clinical Practice by McKnight, Dianalee, Morales, Ana, Hatchell, Kathryn E, Bristow, Sara L, Bonkowsky, Joshua L, Perry, Michael Scott, Berg, Anne T, Borlot, Felippe, Esplin, Edward D, Moretz, Chad, Angione, Katie, Ríos-Pohl, Loreto, Nussbaum, Robert L, Aradhya, Swaroop, Haldeman-Englert, Chad R, Levy, Rebecca J, Parachuri, Venu G, Lay-Son, Guillermo, de Montellano, David J Dávila-Ortiz, Ramirez-Garcia, Miguel Angel, Benítez Alonso, Edmar O, Ziobro, Julie, Chirita-Emandi, Adela, Felix, Temis M, Kulasa-Luke, Dianne, Megarbane, Andre, Karkare, Shefali, Chagnon, Sarah L, Humberson, Jennifer B, Assaf, Melissa J, Silva, Sebastian, Zarroli, Katherine, Boyarchuk, Oksana, Nelson, Gary R, Palmquist, Rachel, Hammond, Katherine C, Hwang, Sean T, Boutlier, Susan B, Nolan, Melinda, Batley, Kaitlin Y, Chavda, Devraj, Reyes-Silva, Carlos Alberto, Miroshnikov, Oleksandr, Zuccarelli, Britton, Amlie-Wolf, Louise, Wheless, James W, Seinfeld, Syndi, Kanhangad, Manoj, Freeman, Jeremy L, Monroy-Santoyo, Susana, Rodriguez-Vazquez, Natalia, Ryan, Monique M, Machie, Michelle, Guerra, Patricio, Hassan, Muhammad Jawad, Candee, Meghan S, Bupp, Caleb P, Park, Kristen L, Muller, 2nd, Eric, Lupo, Pamela, Pedersen, Robert C, Arain, Amir M, Murphy, Andrea, Schatz, Krista, Mu, Weiyi, Kalika, Paige M, Plaza, Lautaro, Kellogg, Marissa A, Lora, Evelyn G, Carson, Robert P, Svystilnyk, Victoria, Venegas, Viviana, Luke, Rebecca R, Jiang, Huiyuan, Stetsenko, Tetiana, Dueñas-Roque, Milagros M, Trasmonte, Joseph, Burke, Rebecca J, Hurst, Anna C E, Smith, Douglas M, Massingham, Lauren J, Pisani, Laura, Costin, Carrie E, Ostrander, Betsy, Filloux, Francis M, Ananth, Amitha L, Mohamed, Ismail S, Nechai, Alla, Dao, Jasmin M, Fahey, Michael C, Aliu, Ermal, Falchek, Stephen, Press, Craig A, Treat, Lauren, Eschbach, Krista, Starks, Angela, Kammeyer, Ryan, Bear, Joshua J, Jacobson, Mona, Chernuha, Veronika

“…It is currently unknown how often and in which ways a genetic diagnosis given to a patient with epilepsy is associated with clinical management and outcomes…”
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EEG reactivity in neurologic prognostication in post-cardiac arrest patients: A narrative review by Fahrner, Marlen G., Hwang, Jaeho, Cho, Sung-Min, Thakor, Nitish V., Habela, Christa W., Kaplan, Peter W., Geocadin, Romergryko G.

“…Electroencephalographic reactivity (EEG-R) is a promising early predictor of arousal in comatose patients after cardiac arrest. Despite recent guidelines…”
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Continuous Electroencephalography (EEG) Protocol Improves Seizure Detection in Children on Extracorporeal Membrane Oxygenation by deCampo, Danielle, Husari, Khalil S., Bembea, Melania M., Habela, Christa W., Ritzl, Eva K.

“…Background / Objective Seizures are a complication for pediatric patients requiring extracorporeal membrane oxygenation (ECMO). There are no standardized…”
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Chloride Accumulation Drives Volume Dynamics Underlying Cell Proliferation and Migration by Habela, Christa W, Ernest, Nola Jean, Swindall, Amanda F, Sontheimer, Harald

“…Department of Neurobiology, Center for Glial Biology in Medicine, University of Alabama, Birmingham, Alabama Submitted 31 July 2008; accepted in final form 20…”
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Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins by Yoon, Ki-Jun, Song, Guang, Qian, Xuyu, Pan, Jianbo, Xu, Dan, Rho, Hee-Sool, Kim, Nam-Shik, Habela, Christa, Zheng, Lily, Jacob, Fadi, Zhang, Feiran, Lee, Emily M., Huang, Wei-Kai, Ringeling, Francisca Rojas, Vissers, Caroline, Li, Cui, Yuan, Ling, Kang, Koeun, Kim, Sunghan, Yeo, Junghoon, Cheng, Yichen, Liu, Sheng, Wen, Zhexing, Qin, Cheng-Feng, Wu, Qingfeng, Christian, Kimberly M., Tang, Hengli, Jin, Peng, Xu, Zhiheng, Qian, Jiang, Zhu, Heng, Song, Hongjun, Ming, Guo-li

“…Zika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV interacts with the host molecular machinery to impact…”
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Spatiotemporal coordination of actin regulators generates invasive protrusions in cell–cell fusion by Lu, Yue, Walji, Tezin, Ravaux, Benjamin, Pandey, Pratima, Yang, Changsong, Li, Bing, Luvsanjav, Delgermaa, Lam, Kevin H., Zhang, Ruihui, Luo, Zhou, Zhou, Chuanli, Habela, Christa W., Snapper, Scott B., Li, Rong, Goldhamer, David J., Schmidtke, David W., Pan, Duojia, Svitkina, Tatyana M., Chen, Elizabeth H.

“…Invasive membrane protrusions play a central role in a variety of cellular processes. Unlike filopodia, invasive protrusions are mechanically stiff and…”
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Pediatric Epilepsy Mechanisms: Expanding the Paradigm of Excitation/Inhibition Imbalance by Shao, Li-Rong, Habela, Christa W, Stafstrom, Carl E

“…Mechanisms underlying seizures and epilepsy have traditionally been considered to involve abnormalities of ion channels or synaptic function. Those…”
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ClC3 Is a Critical Regulator of the Cell Cycle in Normal and Malignant Glial Cells by Habela, Christa W, Olsen, Michelle L, Sontheimer, Harald

“…Although most brain cells are postmitotic, small populations of progenitor or stem cells can divide throughout life. These cells are believed to be the most…”
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Cytoplasmic Volume Condensation Is an Integral Part of Mitosis by Habela, Christa W., Sontheimer, Harald

“…Cell growth and osmotic volume regulation are undoubtedly linked to the progression of the cell cycle as with each division, a newly generated cell must…”
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Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons by Taga, Arens, Habela, Christa W, Johns, Alexandra, Liu, Shiyu, O'Brien, Mollie, Maragakis, Nicholas J

“…Human pluripotent stem cell-derived astrocytes (hiPSC-A) and neurons (hiPSC-N) provide a powerful tool for modeling Amyotrophic Lateral Sclerosis (ALS)…”
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Focused Ultrasound Neuromodulation of Human In Vitro Neural Cultures in Multi-Well Microelectrode Arrays by Liang, Ruixing, Mess, Griffin, Punnoose, Joshua, Kempski Leadingham, Kelley M, Smit, Constantin, Thakor, Nitish, Habela, Christa W, Tyler, Betty, Salimpour, Yousef, Manbachi, Amir

“…The neuromodulatory effects of focused ultrasound (FUS) have been demonstrated in animal models, and FUS has been used successfully to treat movement and…”
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Cytoplasmic condensation is both necessary and sufficient to induce apoptotic cell death by Ernest, Nola Jean, Habela, Christa W, Sontheimer, Harald

“…Programmed cell death (apoptosis) is important in tissue maintenance. Hallmarks of apoptosis include caspase activation, DNA fragmentation and an overall…”
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Role of Human‐Induced Pluripotent Stem Cell‐Derived Spinal Cord Astrocytes in the Functional Maturation of Motor Neurons in a Multielectrode Array System by Taga, Arens, Dastgheyb, Raha, Habela, Christa, Joseph, Jessica, Richard, Jean‐Philippe, Gross, Sarah K., Lauria, Giuseppe, Lee, Gabsang, Haughey, Norman, Maragakis, Nicholas J.

“…The ability to generate human‐induced pluripotent stem cell (hiPSC)‐derived neural cells displaying region‐specific phenotypes is of particular interest for…”
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Hypothermic Protection in Neocortex Is Topographic and Laminar, Seizure Unmitigating, and Partially Rescues Neurons Depleted of RNA Splicing Protein Rbfox3/NeuN in Neonatal Hypoxic-Ischemic Male Piglets by Primiani, Christopher T, Lee, Jennifer K, O'Brien, Caitlin E, Chen, May W, Perin, Jamie, Kulikowicz, Ewa, Santos, Polan, Adams, Shawn, Lester, Bailey, Rivera-Diaz, Natalia, Olberding, Valerie, Niedzwiecki, Mark V, Ritzl, Eva K, Habela, Christa W, Liu, Xiuyun, Yang, Zeng-Jin, Koehler, Raymond C, Martin, Lee J

“…The effects of hypothermia on neonatal encephalopathy may vary topographically and cytopathologically in the neocortex with manifestations potentially…”
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P567: Innovations in education: Empowering child neurology residents with basic concepts in genomic testing through a national curriculum by Sen, Kuntal, Ananth, Amitha, Gottlieb-Smith, Rachel, Calalme, Daniel, Strelzik, Jeffrey, Baranano, Kristin, Emrick, Lisa, Ziobro, Julie, Habela, Christa, Ream, Margie, Mithal, Divakar, Gropman, Andrea, Dang, Louis

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Kinase activation of ClC-3 accelerates cytoplasmic condensation during mitotic cell rounding by Cuddapah, Vishnu Anand, Habela, Christa W, Watkins, Stacey, Moore, Lindsay S, Barclay, Tia-Tabitha C, Sontheimer, Harald

“…"Mitotic cell rounding" describes the rounding of mammalian cells before dividing into two daughter cells. This shape change requires coordinated cytoskeletal…”
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Continuous EEG (cEEG) protocol improves seizure detection in children on extracorporeal membrane oxygenation (ECMO) by deCampo, Danielle, Husari, Khalil S., Bembea, Melania M., Habela, Christa W., Ritzl, Eva K.

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Genetic Testing in Epilepsy: Improving Outcomes and Informing Gaps in Research by Habela, Christa W., Schatz, Krista, Kelley, Sarah A.

“…While the diagnosis of epilepsy relies on the presence of seizures, it encompasses a group of phenotypically and etiologically diverse disorders in which…”
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