Search Results - "Habecker, Beth"
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Identifying vagal sensory neurons driving the Bezold-Jarisch reflex
Published in Trends in neurosciences (Regular ed.) (01-02-2024)“…Homeostatic reflexes are crucial for life, but the subpopulations of sensory neurons that stimulate these reflexes are largely unknown. A recent paper from…”
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What gets on the nerves of cardiac patients? Pathophysiological changes in cardiac innervation
Published in The Journal of physiology (01-02-2022)“…The autonomic nervous system regulates cardiac function by balancing the actions of sympathetic and parasympathetic inputs to the heart. Intrinsic cardiac…”
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A primer on incorporating sex as a biological variable into the conduct and reporting of basic and clinical research studies
Published in American journal of physiology. Heart and circulatory physiology (01-03-2022)“…The recent move to require sex as a biological variable (SABV), which includes gender, into the reporting of research published by the follows a growing, and…”
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4
Hypertension increases sympathetic neuron activity by enhancing intraganglionic cholinergic collateral connections
Published in The Journal of physiology (21-06-2024)“…Autonomic dysregulation, including sympathetic hyperactivity, is a common feature of hypertension (HT) and other cardiovascular diseases. The CNS plays a role…”
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Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease
Published in The Journal of physiology (15-07-2016)“…The nervous system and cardiovascular system develop in concert and are functionally interconnected in both health and disease. This white paper focuses on the…”
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Infarct-derived chondroitin sulfate proteoglycans prevent sympathetic reinnervation after cardiac ischemia-reperfusion injury
Published in The Journal of neuroscience (24-04-2013)“…Sympathetic nerves can regenerate after injury to reinnervate target tissues. Sympathetic regeneration is well documented after chronic cardiac ischemia, so we…”
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Evidence for Cholinergic Collateral Projections between Sympathetic Neurons in the Murine Stellate Ganglia
Published in The FASEB journal (01-05-2022)“…Postganglionic neurons of the stellate ganglia (SG) are an integral component of sympathetic regulation of the heart. SG neurons receive preganglionic…”
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Sex differences in sympathetic gene expression and cardiac neurochemistry in Wistar Kyoto rats
Published in PloS one (13-06-2019)“…The stellate ganglia are the predominant source of sympathetic innervation to the heart. Remodeling of sympathetic nerves projecting to the heart has been…”
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Systemic Inhibition of CREB is Well-tolerated in vivo
Published in Scientific reports (03-10-2016)“…cAMP-response element binding protein (CREB) is a nuclear transcription factor activated by multiple extracellular signals including growth factors and…”
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10
Cholinergic collaterals arising from noradrenergic sympathetic neurons in mice
Published in The Journal of physiology (01-04-2023)“…The sympathetic nervous system vitally regulates autonomic functions, including cardiac activity. Postganglionic neurons of the sympathetic chain ganglia relay…”
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11
Diverse Morphology of Sympathetic Neuron Subpopulations in the Stellate Ganglia
Published in The FASEB journal (01-05-2022)“…Sympathetic nerves innervate the heart and changes in sympathetic efferent activity can modulate cardiac function. The post‐ganglionic sympathetic neurons that…”
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12
Unraveling the lost balance: Adrenergic dysfunction in cancer cachexia
Published in Autonomic neuroscience (01-02-2024)“…Cancer cachexia, characterized by muscle wasting and widespread inflammation, poses a significant challenge for patients with cancer, profoundly impacting both…”
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13
Characterizing Sex Differences in Physical Frailty Phenotypes in Heart Failure
Published in Circulation. Heart failure (01-09-2021)“…Although women with heart failure (HF) are potentially more likely to be physically frail compared with men with HF, the underlying contributors to this sex…”
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14
Molecular Mechanisms of Sympathetic Remodeling and Arrhythmias
Published in Circulation. Arrhythmia and electrophysiology (01-02-2016)Get full text
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15
Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130
Published in The Journal of neuroscience (13-01-2016)“…Sympathetic and parasympathetic control of the heart is a classic example of norepinephrine (NE) and acetylcholine (ACh) triggering opposing actions…”
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Guidelines on the use of sex and gender in cardiovascular research
Published in American journal of physiology. Heart and circulatory physiology (01-01-2024)“…In cardiovascular research, sex and gender have not typically been considered in research design and reporting until recently. This has resulted in clinical…”
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STAT3 integrates cytokine and neurotrophin signals to promote sympathetic axon regeneration
Published in Molecular and cellular neuroscience (01-09-2013)“…The transcription factor STAT3 has been implicated in axon regeneration. Here we investigate a role for STAT3 in sympathetic nerve sprouting after myocardial…”
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18
Chronic nicotine exposure is associated with electrophysiological and sympathetic remodeling in the intact rabbit heart
Published in American journal of physiology. Heart and circulatory physiology (01-06-2024)“…Nicotine is the primary addictive component of tobacco products. Through its actions on the heart and autonomic nervous system, nicotine exposure is associated…”
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19
Molecular and cellular neurocardiology in heart disease
Published in The Journal of physiology (22-05-2024)“…This paper updates and builds on a previous White Paper in this journal that some of us contributed to concerning the molecular and cellular basis of cardiac…”
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20
Sympathetic structural and electrophysiological remodeling in a rabbit model of reperfused myocardial infarction
Published in American journal of physiology. Heart and circulatory physiology (01-09-2024)“…Chondroitin sulfate proteoglycans (CSPGs) inhibit sympathetic reinnervation in rodent hearts post-myocardial infarction (MI), causing regional hypoinnervation…”
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