Search Results - "Haase, Max A.B."

macroH2A1 drives nucleosome dephasing and genome instability in histone humanized yeast by Haase, Max A.B., Lazar-Stefanita, Luciana, Ólafsson, Guðjón, Wudzinska, Aleksandra, Shen, Michael J., Truong, David M., Boeke, Jef D.

“…In addition to replicative histones, eukaryotic genomes encode a repertoire of non-replicative variant histones, providing additional layers of structural and…”
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Pathogenic budding yeasts isolated outside of clinical settings by Opulente, Dana A, Langdon, Quinn K, Buh, Kelly V, Haase, Max A B, Sylvester, Kayla, Moriarty, Ryan V, Jarzyna, Martin, Considine, Samantha L, Schneider, Rachel M, Hittinger, Chris Todd

“…ABSTRACT Budding yeasts are distributed across a wide range of habitats, including as human commensals. However, under some conditions, these commensals can…”
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Tempo and Mode of Genome Evolution in the Budding Yeast Subphylum by Shen, Xing-Xing, Opulente, Dana A., Kominek, Jacek, Zhou, Xiaofan, Steenwyk, Jacob L., Buh, Kelly V., Haase, Max A.B., Wisecaver, Jennifer H., Wang, Mingshuang, Doering, Drew T., Boudouris, James T., Schneider, Rachel M., Langdon, Quinn K., Ohkuma, Moriya, Endoh, Rikiya, Takashima, Masako, Manabe, Ri-ichiroh, Čadež, Neža, Libkind, Diego, Rosa, Carlos A., DeVirgilio, Jeremy, Hulfachor, Amanda Beth, Groenewald, Marizeth, Kurtzman, Cletus P., Hittinger, Chris Todd, Rokas, Antonis

“…Budding yeasts (subphylum Saccharomycotina) are found in every biome and are as genetically diverse as plants or animals. To understand budding…”
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Gene loss and cis-regulatory novelty shaped core histone gene evolution in the apiculate yeast Hanseniaspora uvarum by Haase, Max A B, Steenwyk, Jacob L, Boeke, Jef D

“…Abstract Core histone genes display a remarkable diversity of cis-regulatory mechanisms despite their protein sequence conservation. However, the dynamics and…”
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Two differentially stable rDNA loci coexist on the same chromosome and form a single nucleolus by Lazar-Stefanita, Luciana, Luo, Jingchuan, Haase, Max A B, Zhang, Weimin, Boeke, Jef D

“…The nucleolus is the most prominent membraneless compartment within the nucleus-dedicated to the metabolism of ribosomal RNA. Nucleoli are composed of hundreds…”
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Protein–protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning by MacRae, Mark R., Puvanendran, Dhenesh, Haase, Max A.B., Coudray, Nicolas, Kolich, Ljuvica, Lam, Cherry, Baek, Minkyung, Bhabha, Gira, Ekiert, Damian C.

“…The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer that protects the cell from external stressors, such as antibiotics. The Mla…”
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Taxogenomic analysis of a novel yeast species isolated from soil, Pichia galeolata sp. nov by Opulente, Dana A., Langdon, Quinn K., Jarzyna, Martin, Buh, Kelly V., Haase, Max A. B., Groenewald, Marizeth, Hittinger, Chris Todd

“…A novel budding yeast species was isolated from a soil sample collected in the United States of America. Phylogenetic analyses of multiple loci and…”
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Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples by O'Brien, Caoimhe E, Oliveira-Pacheco, João, Ó Cinnéide, Eoin, Haase, Max A B, Hittinger, Chris Todd, Rogers, Thomas R, Zaragoza, Oscar, Bond, Ursula, Butler, Geraldine

“…Candida tropicalis is a human pathogen that primarily infects the immunocompromised. Whereas the genome of one isolate, C. tropicalis MYA-3404, was originally…”
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DASH/Dam1 complex mutants stabilize ploidy in histone‐humanized yeast by weakening kinetochore‐microtubule attachments by Haase, Max A B, Ólafsson, Guðjón, Flores, Rachel L, Boakye‐Ansah, Emmanuel, Zelter, Alex, Dickinson, Miles Sasha, Lazar‐Stefanita, Luciana, Truong, David M, Asbury, Charles L, Davis, Trisha N, Boeke, Jef D

“…Forcing budding yeast to chromatinize their DNA with human histones manifests an abrupt fitness cost. We previously proposed chromosomal aneuploidy and…”
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Repeated horizontal gene transfer of GALactose metabolism genes violates Dollo’s law of irreversible loss by Haase, Max A B, Kominek, Jacek, Opulente, Dana A, Shen, Xing-Xing, LaBella, Abigail L, Zhou, Xiaofan, DeVirgilio, Jeremy, Hulfachor, Amanda Beth, Kurtzman, Cletus P, Rokas, Antonis, Hittinger, Chris Todd

“…Abstract Dollo’s law posits that evolutionary losses are irreversible, thereby narrowing the potential paths of evolutionary change. While phenotypic reversals…”
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Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts by Opulente, Dana A, LaBella, Abigail Leavitt, Harrison, Marie-Claire, Wolters, John F, Liu, Chao, Li, Yonglin, Kominek, Jacek, Steenwyk, Jacob L, Stoneman, Hayley R, VanDenAvond, Jenna, Miller, Caroline R, Langdon, Quinn K, Silva, Margarida, Gonçalves, Carla, Ubbelohde, Emily J, Li, Yuanning, Buh, Kelly V, Jarzyna, Martin, Haase, Max A B, Rosa, Carlos A, ČCadež, Neža, Libkind, Diego, DeVirgilio, Jeremy H, Hulfachor, Amanda Beth, Kurtzman, Cletus P, Sampaio, José Paulo, Gonçalves, Paula, Zhou, Xiaofan, Shen, Xing-Xing, Groenewald, Marizeth, Rokas, Antonis, Hittinger, Chris Todd

“…Organisms exhibit extensive variation in ecological niche breadth, from very narrow (specialists) to very broad (generalists). Two general paradigms have been…”
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Substrate, temperature, and geographical patterns among nearly 2000 natural yeast isolates by Spurley, William J., Fisher, Kaitlin J., Langdon, Quinn K., Buh, Kelly V., Jarzyna, Martin, Haase, Max A. B., Sylvester, Kayla, Moriarty, Ryan V., Rodriguez, Daniel, Sheddan, Angela, Wright, Sarah, Sorlie, Lisa, Hulfachor, Amanda Beth, Opulente, Dana A., Hittinger, Chris Todd

“…Yeasts have broad importance as industrially and clinically relevant microbes and as powerful models for fundamental research, but we are only beginning to…”
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Microbial Diversity Associated with the Pollen Stores of Captive-Bred Bumble Bee Colonies by Dharampal, Prarthana S, Diaz-Garcia, Luis, Haase, Max A B, Zalapa, Juan, Currie, Cameron R, Hittinger, Chris Todd, Steffan, Shawn A

“…The pollen stores of bumble bees host diverse microbiota that influence overall colony fitness. Yet, the taxonomic identity of these symbiotic microbes is…”
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Genome sequence and physiological analysis of Yamadazyma laniorum f.a. sp. nov. and a reevaluation of the apocryphal xylose fermentation of its sister species, Candida tenuis by Haase, Max A. B., Kominek, Jacek, Langdon, Quinn K., Kurtzman, Cletus P., Hittinger, Chris Todd

“…Abstract Xylose fermentation is a rare trait that is immensely important to the cellulosic biofuel industry, and Candida tenuis is one of the few yeasts that…”
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Superloser: A Plasmid Shuffling Vector for Saccharomyces cerevisiae with Exceedingly Low Background by Haase, Max A B, Truong, David M, Boeke, Jef D

“…Here we report a new plasmid shuffle vector for forcing budding yeast ( ) to incorporate a new genetic pathway in place of a native pathway - even an essential…”
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Context-dependent neocentromere activity in synthetic yeast chromosome VIII by Lauer, Stephanie, Luo, Jingchuan, Lazar-Stefanita, Luciana, Zhang, Weimin, McCulloch, Laura H, Fanfani, Viola, Lobzaev, Evgenii, Haase, Max A B, Easo, Nicole, Zhao, Yu, Yu, Fangzhou, Cai, Jitong, Bader, Joel S, Stracquadanio, Giovanni, Boeke, Jef D

“…Pioneering advances in genome engineering, and specifically in genome writing, have revolutionized the field of synthetic biology, propelling us toward the…”
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