Search Results - "Haase, G."

Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression by Shvab, A, Haase, G, Ben-Shmuel, A, Gavert, N, Brabletz, T, Dedhar, S, Ben-Ze'ev, A

“…Overactivation of Wnt-β-catenin signaling, including β-catenin-TCF target gene expression, is a hallmark of colorectal cancer (CRC) development. We identified…”
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White-nose syndrome, winter duration, and pre-hibernation climate impact abundance of reproductive female bats by Krueger, Sarah K, Williams, Sarah C, O'Keefe, Joy M, Zirkle, Gene A, Haase, Catherine G

“…White-nose syndrome (WNS) is an infectious disease that disrupts hibernation in bats, leading to premature exhaustion of fat stores. Though we know WNS does…”
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Safety and efficacy of ALD403, an antibody to calcitonin gene-related peptide, for the prevention of frequent episodic migraine: a randomised, double-blind, placebo-controlled, exploratory phase 2 trial by Dodick, David W, Prof, Goadsby, Peter J, Prof, Silberstein, Stephen D, Prof, Lipton, Richard B, Prof, Olesen, Jes, Prof, Ashina, Messoud, Prof, Wilks, Kerri, MD, Kudrow, David, MD, Kroll, Robin, MD, Kohrman, Bruce, MD, Bargar, Robert, MD, Hirman, Joe, PhD, Smith, Jeff, MD

“…Summary Background Calcitonin gene-related peptide (CGRP) is crucial in the pathophysiology of migraine. We assessed the safety, tolerability, and efficacy of…”
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Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors by STRUMBERG, Dirk, RICHLY, Heike, SCHWARTZ, Brian, AWADA, Ahmad, VOIGTMANN, Rudolf, SCHEULEN, Max E, SEEBER, Siegfried, HILGER, Ralf A, SCHLEUCHER, Norbert, KORFEE, Sonke, TEWES, Mitra, FAGHIH, Markus, BRENDEL, Erich, VOLIOTIS, Dimitris, HAASE, Claus G

“…BAY 43-9006 is a novel dual-action Raf kinase and vascular endothelial growth factor receptor inhibitor that inhibits tumor cell proliferation and…”
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A point mutation in the extracellular domain of L1 blocks its capacity to confer metastasis in colon cancer cells via CD10 by Haase, G, Gavert, N, Brabletz, T, Ben-Ze'ev, A

“…The neural L1 transmembrane cell adhesion receptor of the immunoglobulin-like family is a target gene of Wnt-β-catenin signaling in human colorectal cancer…”
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Glia and epilepsy: Experimental investigation of antiepileptic drugs in an astroglia/microglia co‐culture model of inflammation by Dambach, Hannes, Hinkerohe, Daniel, Prochnow, Nora, Stienen, Martin N., Moinfar, Zahra, Haase, Claus G., Hufnagel, Andreas, Faustmann, Pedro M.

“…Summary Purpose The contribution of glial cells, mainly astrocytes and microglia, to the pathophysiology of epilepsy is increasingly appreciated. Glia play a…”
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Prevalence and characterization of azole-resistant Aspergillus fumigatus in patients with cystic fibrosis: a prospective multicentre study in Germany by Seufert, R, Sedlacek, L, Kahl, B, Hogardt, M, Hamprecht, A, Haase, G, Gunzer, F, Haas, A, Grauling-Halama, S, MacKenzie, C R, Essig, A, Stehling, F, Sutharsan, S, Dittmer, S, Killengray, D, Schmidt, D, Eskandarian, N, Steinmann, E, Buer, J, Hagen, F, Meis, J F, Rath, P-M, Steinmann, J

“…Aspergillus fumigatus is the most prevalent filamentous fungus in the respiratory tract of patients with cystic fibrosis (CF). The aim of this prospective…”
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Prospective surveillance of drain associated meningitis/ventriculitis in a neurosurgery and neurological intensive care unit by Scheithauer, S, Bürgel, U, Ryang, Y-M, Haase, G, Schiefer, J, Koch, S, Häfner, H, Lemmen, S

“…Objectives:There are currently no data available on drain associated infection occurrence related to the number of drainage days (DD), and thus drain…”
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Accelerating Cardiac Bidomain Simulations Using Graphics Processing Units by Neic, Aurel, Liebmann, Manfred, Hoetzl, Elena, Mitchell, Lawrence, Vigmond, Edward J., Haase, Gundolf, Plank, Gernot

“…Anatomically realistic and biophysically detailed multiscale computer models of the heart are playing an increasingly important role in advancing our…”
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Phase I safety and pharmacokinetics of BAY 43-9006 administered for 21 days on 7 days off in patients with advanced, refractory solid tumours by AWADA, A, HENDLISZ, A, PICCART, M, GIL, T, BARTHOLOMEUS, S, MANO, M, DE VALERIOLA, D, STRUMBERG, D, BRENDEL, E, HAASE, C. G, SCHWARTZ, B

“…BAY 43-9006 is a novel dual-action Raf kinase and vascular endothelial growth factor receptor (VEGFR) inhibitor that targets tumour cell proliferation and…”
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Sequence-based identification of Aspergillus, fusarium, and mucorales species in the clinical mycology laboratory: where are we and where should we go from here? by Balajee, S A, Borman, A M, Brandt, M E, Cano, J, Cuenca-Estrella, M, Dannaoui, E, Guarro, J, Haase, G, Kibbler, C C, Meyer, W, O'Donnell, K, Petti, C A, Rodriguez-Tudela, J L, Sutton, D, Velegraki, A, Wickes, B L

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Loess in Europe—its spatial distribution based on a European Loess Map, scale 1:2,500,000 by Haase, D., Fink, J., Haase, G., Ruske, R., Pécsi, M., Richter, H., Altermann, M., Jäger, K.-D.

“…The paper focuses on the concept, mapping and discussion of loess distribution in Western, Central and Eastern Europe at a scale of 1:2,500,000. The research…”
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Antagonizing dabigatran by idarucizumab in cases of ischemic stroke or intracranial hemorrhage in Germany – A national case collection by Kermer, Pawel, Eschenfelder, Christoph C, Diener, Hans-Christoph, Grond, Martin, Abdalla, Yasser, Althaus, Katharina, Berrouschot, Jörg, Cangür, Hakan, Daffertshofer, Michael, Edelbusch, Sebastian, Gröschel, Klaus, Haase, Claus G, Harloff, Andreas, Held, Valentin, Kauert, Andreas, Kraft, Peter, Lenz, Arne, Müllges, Wolfgang, Obermann, Mark, Partowi, Someieh, Purrucker, Jan, Ringleb, Peter A, Röther, Joachim, Rossi, Raluca, Schäfer, Niklas, Schneider, Andreas, Schuppner, Ramona, Seitz, Rüdiger J, Szabo, Kristina, Wruck, Robert

“…Background Idarucizumab is a monoclonal antibody fragment with high affinity for dabigatran that reverses its anticoagulant effects within minutes. It may…”
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A highly effective emitter substance for mass spectrometric Pb isotope ratio determinations by Gerstenberger, H., Haase, G.

“…A new emitter substance for lead isotope measurements consisting of a mixture of colloidal silicic acid and dilute phosphoric acid is described. With respect…”
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Interspecific variation in evaporative water loss and temperature response, but not metabolic rate, among hibernating bats by McGuire, Liam P., Fuller, Nathan W., Dzal, Yvonne A., Haase, Catherine G., Klüg-Baerwald, Brandon J., Silas, Kirk A., Plowright, Raina K., Lausen, Cori L., Willis, Craig K. R., Olson, Sarah H.

“…Hibernation is widespread among mammals in a variety of environmental contexts. However, few experimental studies consider interspecific comparisons, which may…”
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Prevalence of Scedosporium species and Lomentospora prolificans in patients with cystic fibrosis in a multicenter trial by use of a selective medium by Sedlacek, L, Graf, B, Schwarz, C, Albert, F, Peter, S, Würstl, B, Wagner, S, Klotz, M, Becker, A, Haase, G, Laniado, G, Kahl, B, Suerbaum, S, Seibold, M, Tintelnot, K

“…Abstract Objective Detection of hyphomycetes of the Scedosporium apiospermum complex and Lomentospora prolificans ( Sa c- Lp ) is not yet standardized…”
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Traveling to thermal refuges during stressful temperatures leads to foraging constraints in a central-place forager by Haase, Catherine G., Fletcher, Robert J., Slone, Daniel H., Reid, James P., Butler, Susan M.

“…Central-place foragers can be constrained by the distance between habitats. When an organism relies on a central place for thermal refuge, the distance to food…”
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The Developmental Trajectory of the Operational Momentum Effect by Pinheiro-Chagas, Pedro, Didino, Daniele, Haase, Vitor G, Wood, Guilherme, Knops, André

“…Mental calculation is thought to be tightly related to visuospatial abilities. One of the strongest evidence for this link is the widely replicated operational…”
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Quality of thermal refuges influences use by the cold-intolerant Florida manatee by Haase, CG, Fletcher, RJ, Jr, Slone, DH, Reid, JP, Butler, SM

“…Thermal refuges are habitats used by species for behavioral thermoregulation. These habitats can be highly dynamic and are often influenced by fluctuations in…”
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Incorporating evaporative water loss into bioenergetic models of hibernation to test for relative influence of host and pathogen traits on white-nose syndrome by Haase, Catherine G, Fuller, Nathan W, Hranac, C Reed, Hayman, David T S, McGuire, Liam P, Norquay, Kaleigh J O, Silas, Kirk A, Willis, Craig K R, Plowright, Raina K, Olson, Sarah H

“…Hibernation consists of extended durations of torpor interrupted by periodic arousals. The 'dehydration hypothesis' proposes that hibernating mammals arouse to…”
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