Search Results - "Haas‐Kogan, Daphne"
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Response rate and local recurrence after concurrent immune checkpoint therapy and radiotherapy for non–small cell lung cancer and melanoma brain metastases
Published in Cancer (15-12-2020)“…Background Prior literature has suggested synergy between immune checkpoint therapy (ICT) and radiotherapy (RT) for the treatment of brain metastases (BrM),…”
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Risk stratification by somatic mutation burden in Ewing sarcoma
Published in Cancer (15-04-2019)“…Background Up to one‐third of patients with localized Ewing sarcoma (ES) develop recurrent disease, but current biomarkers do not accurately identify this…”
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A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
Published in Cancer cell (12-09-2022)“…Diffuse midline glioma (DMG) is a uniformly fatal pediatric cancer driven by oncohistones that do not readily lend themselves to drug development. To identify…”
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“Per protocol” practice patterns for Children's Oncology Group trials within the radiation oncology community
Published in Pediatric blood & cancer (01-08-2023)“…Little is known about the prevalence of pediatric radiation oncologists treating patients off study according to Children's Oncology Group (COG) trials before…”
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Therapeutic radiation and the potential risk of second malignancies
Published in Cancer (15-06-2016)“…Radiation has long been associated with carcinogenesis. Nevertheless, it is an important part of multimodality therapy for many malignancies. It is critical to…”
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Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial
Published in The lancet oncology (01-09-2013)“…Summary Background Myeloablative chemoradiotherapy and immunomagnetically purged autologous bone marrow transplantation has been shown to improve outcome for…”
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Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era
Published in Neoplasia (New York, N.Y.) (01-02-2023)“…•Pediatric low-grade glioma (pLGG) is a MAPK pathway-altered disease with novel therapeutic options.•Clinical trials are vital in translation of targeted…”
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Clinical outcomes for pediatric patients receiving radiotherapy for solid tumor central nervous system metastases
Published in Pediatric blood & cancer (01-12-2021)“…Central nervous system (CNS) metastases are rare, but devastating complications of pediatric solid tumors. Radiotherapy alone or postresection serves as an…”
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Treating the SARS‐CoV‐2–positive patient with cancer: A proposal for a pragmatic and transparent ethical process
Published in Cancer (01-09-2020)“…The treatment of patients with cancer who test positive for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) poses unique challenges. In this…”
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Children's Oncology Group's 2023 blueprint for research: Radiation oncology
Published in Pediatric blood & cancer (01-09-2023)“…Radiation oncology is an integral part of the multidisciplinary team caring for children with cancer. The primary goal of our committee is to enable the…”
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Gliomas, germ cell tumors, and craniopharyngioma
Published in Pediatric blood & cancer (01-05-2021)“…This report summarizes the current multimodality treatment approaches for children with low‐ and high‐grade gliomas, germinoma, and nongerminomatous germ cell…”
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Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors
Published in Pediatric blood & cancer (01-09-2023)“…Tumors of the central nervous system (CNS) are a leading cause of morbidity and mortality in the pediatric population. Molecular characterization in the last…”
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Pediatric high-grade glioma: biologically and clinically in need of new thinking
Published in Neuro-oncology (Charlottesville, Va.) (01-02-2017)“…High-grade gliomas in children are different from those that arise in adults. Recent collaborative molecular analyses of these rare cancers have revealed…”
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Practice patterns and recommendations for pediatric image‐guided radiotherapy: A Children's Oncology Group report
Published in Pediatric blood & cancer (01-10-2020)“…This report by the Radiation Oncology Discipline of Children's Oncology Group (COG) describes the practice patterns of pediatric image‐guided radiotherapy…”
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Long‐term outcomes of pediatric and young adult patients receiving radiotherapy for nonmalignant vascular anomalies
Published in Pediatric blood & cancer (01-06-2021)“…Background Nonmalignant vascular anomalies (VA) comprise a heterogeneous spectrum of conditions characterized by aberrant growth or development of blood and/or…”
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Phase I study of vorinostat in combination with isotretinoin in patients with refractory/recurrent neuroblastoma: A new approaches to Neuroblastoma Therapy (NANT) trial
Published in Pediatric blood & cancer (01-07-2018)“…Background Vorinostat combined with retinoids produces additive antitumor effects in preclinical studies of neuroblastoma. Higher systemic exposures of…”
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Outcomes after first relapse of childhood intracranial ependymoma
Published in Pediatric blood & cancer (01-08-2021)“…Background Ependymoma is the third most common malignant CNS tumor in children. Despite multimodal therapy, prognosis of relapsed ependymoma remains poor…”
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PDGFRA Amplification is Common in Pediatric and Adult High-Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma
Published in Brain pathology (Zurich, Switzerland) (01-09-2013)“…High‐grade astrocytomas (HGAs), corresponding to World Health Organization grades III (anaplastic astrocytoma) and IV (glioblastoma; GBM), are biologically…”
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Role of the extent of prophylactic regional lymph node radiotherapy on survival in high‐risk neuroblastoma: A report from the COG A3973 study
Published in Pediatric blood & cancer (01-07-2019)“…Purpose Neuroblastoma is the most common extracranial solid pediatric malignancy, with poor outcomes in high‐risk disease. Standard treatment approaches employ…”
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