Search Results - "Haas, Michael S."
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mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
Published in Molecular cancer research (01-04-2021)“…Dickkopf-1 (DKK1), a secreted modulator of Wnt signaling, is overexpressed in many cancers, is often associated with worse clinical outcomes, and has been…”
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Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice
Published in Blood (20-12-2012)“…Coronary heart disease is a major cause of death in the western world. Although essential for successful recovery, reperfusion of ischemic myocardium is…”
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Validation of a DKK1 RNAscope chromogenic in situ hybridization assay for gastric and gastroesophageal junction adenocarcinoma tumors
Published in Scientific reports (10-05-2021)“…Dickkopf-1 (DKK1) is a secreted modulator of Wnt signaling that is frequently overexpressed in tumors and associated with poor clinical outcomes. DKN-01 is a…”
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Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction
Published in Cardiovascular research (01-09-2010)“…Aims Coronary artery occlusion resulting in ischaemia/reperfusion (I/R) injury is a major cause of mortality in the western world. Circulating natural IgM has…”
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Natural IgM Blockade Limits Infarct Expansion and Left Ventricular Dysfunction in a Swine Myocardial Infarct Model
Published in Circulation. Cardiovascular interventions (01-01-2016)“…BACKGROUND—Acute coronary syndrome is the leading cause of mortality worldwide. However, treatment of acute coronary occlusion inevitably results in…”
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Muscarinic receptor- and phorbol ester-stimulated phosphorylation of protein kinase C substrates in adult and neonatal cortical slices
Published in Brain research. Developmental brain research (12-04-1999)“…The neuron-specific protein B-50 (GAP-43) is a major presynaptic substrate for protein kinase C (PKC). Phosphorylation of B-50 by PKC at serine-41 is…”
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Protective anti-inflammatory effect of ADAMTS 13 on myocardial ischemia/reperfusion injury in mice
Published in Blood (2012)Get full text
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