Search Results - "Haas, Kelsey"

The proteomic landscape of triple-negative breast cancer by Lawrence, Robert T, Perez, Elizabeth M, Hernández, Daniel, Miller, Chris P, Haas, Kelsey M, Irie, Hanna Y, Lee, Su-In, Blau, C Anthony, Villén, Judit

“…Triple-negative breast cancer is a heterogeneous disease characterized by poor clinical outcomes and a shortage of targeted treatment options. To discover…”
Get full text

Evolution of protein phosphorylation across 18 fungal species by Studer, Romain A., Rodriguez-Mias, Ricard A., Haas, Kelsey M., Hsu, Joanne I., Viéitez, Cristina, Solé, Carme, Swaney, Danielle L., Stanford, Lindsay B., Liachko, Ivan, Böttcher, René, Dunham, Maitreya J., de Nadal, Eulàlia, Posas, Francesc, Beltrao, Pedro, Villén, Judit

“…Living organisms have evolved protein phosphorylation, a rapid and versatile mechanism that drives signaling and regulates protein function. We report the…”
Get full text

De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking by Chen, Zhen, Shiozaki, Momoko, Haas, Kelsey M, Skinner, Will M, Zhao, Shumei, Guo, Caiying, Polacco, Benjamin J, Yu, Zhiheng, Krogan, Nevan J, Lishko, Polina V, Kaake, Robyn M, Vale, Ronald D, Agard, David A

“…To understand the molecular mechanisms of cellular pathways, contemporary workflows typically require multiple techniques to identify proteins, track their…”
Get full text

A functional map of HIV-host interactions in primary human T cells by Hiatt, Joseph, Hultquist, Judd F., McGregor, Michael J., Bouhaddou, Mehdi, Leenay, Ryan T., Simons, Lacy M., Young, Janet M., Haas, Paige, Roth, Theodore L., Tobin, Victoria, Wojcechowskyj, Jason A., Woo, Jonathan M., Rathore, Ujjwal, Cavero, Devin A., Shifrut, Eric, Nguyen, Thong T., Haas, Kelsey M., Malik, Harmit S., Doudna, Jennifer A., May, Andrew P., Marson, Alexander, Krogan, Nevan J.

“…Human Immunodeficiency Virus (HIV) relies on host molecular machinery for replication. Systematic attempts to genetically or biochemically define these host…”
Get full text

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins by Hiatt, Joseph, Cavero, Devin A., McGregor, Michael J., Zheng, Weihao, Budzik, Jonathan M., Roth, Theodore L., Haas, Kelsey M., Wu, David, Rathore, Ujjwal, Meyer-Franke, Anke, Bouzidi, Mohamed S., Shifrut, Eric, Lee, Youjin, Kumar, Vigneshwari Easwar, Dang, Eric V., Gordon, David E., Wojcechowskyj, Jason A., Hultquist, Judd F., Fontaine, Krystal A., Pillai, Satish K., Cox, Jeffery S., Ernst, Joel D., Krogan, Nevan J., Marson, Alexander

“…Genome engineering of primary human cells with CRISPR-Cas9 has revolutionized experimental and therapeutic approaches to cell biology, but human…”
Get full text

CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells by Rathore, Ujjwal, Haas, Paige, Easwar Kumar, Vigneshwari, Hiatt, Joseph, Haas, Kelsey M, Bouhaddou, Mehdi, Swaney, Danielle L, Stevenson, Erica, Zuliani-Alvarez, Lorena, McGregor, Michael J, Turner-Groth, Autumn, Ochieng' Olwal, Charles, Bediako, Yaw, Braberg, Hannes, Soucheray, Margaret, Ott, Melanie, Eckhardt, Manon, Hultquist, Judd F, Marson, Alexander, Kaake, Robyn M, Krogan, Nevan J

“…During HIV infection of CD4+ T cells, ubiquitin pathways are essential to viral replication and host innate immune response; however, the role of specific E3…”
Get full text

The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity by Rialdi, Alexander, Hultquist, Judd, Jimenez-Morales, David, Peralta, Zuleyma, Campisi, Laura, Fenouil, Romain, Moshkina, Natasha, Wang, Zhen Zhen, Laffleur, Brice, Kaake, Robyn M., McGregor, Michael J., Haas, Kelsey, Pefanis, Evangelos, Albrecht, Randy A., Pache, Lars, Chanda, Sumit, Jen, Joanna, Ochando, Jordi, Byun, Minji, Basu, Uttiya, García-Sastre, Adolfo, Krogan, Nevan, van Bakel, Harm, Marazzi, Ivan

“…The nuclear RNA exosome is an essential multi-subunit complex that controls RNA homeostasis. Congenital mutations in RNA exosome genes are associated with…”
Get full text

The Proteomic Landscape of Triple-Negative Breast Cancer by Lawrence, Robert T., Perez, Elizabeth M., Hernández, Daniel, Miller, Chris P., Haas, Kelsey M., Irie, Hanna Y., Lee, Su-In, Blau, C. Anthony, Villén, Judit

Get full text

Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy by Martin-Sancho, Laura, Tripathi, Shashank, Rodriguez-Frandsen, Ariel, Pache, Lars, Sanchez-Aparicio, Maite, McGregor, Michael J., Haas, Kelsey M., Swaney, Danielle L., Nguyen, Thong T., Mamede, João I., Churas, Christopher, Pratt, Dexter, Rosenthal, Sara B., Riva, Laura, Nguyen, Courtney, Beltran-Raygoza, Nish, Soonthornvacharin, Stephen, Wang, Guojun, Jimenez-Morales, David, De Jesus, Paul D., Moulton, Hong M., Stein, David A., Chang, Max W., Benner, Chris, Ideker, Trey, Albrecht, Randy A., Hultquist, Judd F., Krogan, Nevan J., García-Sastre, Adolfo, Chanda, Sumit K.

“…The fate of influenza A virus (IAV) infection in the host cell depends on the balance between cellular defence mechanisms and viral evasion strategies. To…”
Get full text

A practical recipe to survey phosphoproteomes by Edelman, William C, Haas, Kelsey M, Hsu, Joanne I, Lawrence, Robert T, Villén, Judit

“…The field of cellular signaling is fueled by the discovery of novel protein phosphorylation events. Phosphoproteomics focuses on the large-scale identification…”
Get more information

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing by Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O'Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J P, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O'Neal, Michael C, Cai, Yiming, Chang, Jason C J, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia

“…A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019…”
Get full text

Systematic Investigation of Host-Pathogen Interactions Identifies Novel Pan-Viral Gene and Drug Targets for Influenza a Viruses and SARS-CoV-2 by Haas, Kelsey

“…Influenza A Virus (IAV) is a recurring infectious respiratory virus that causes seasonal infections and global pandemics. With increasing antiviral drug…”
Get full text

De novo protein identification in mammalian sperm using in situ cryo-electron tomography and AlphaFold2 docking by Chen, Zhen, Shiozaki, Momoko, Haas, Kelsey M., Skinner, Will M., Zhao, Shumei, Guo, Caiying, Polacco, Benjamin J., Yu, Zhiheng, Krogan, Nevan J., Lishko, Polina V., Kaake, Robyn M., Vale, Ronald D., Agard, David A.

“…To understand molecular mechanisms of cellular pathways, contemporary workflows typically require multiple techniques to identify proteins, track their…”
Get full text

Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets by Haas, Kelsey M., McGregor, Michael J., Bouhaddou, Mehdi, Polacco, Benjamin J., Kim, Eun-Young, Nguyen, Thong T., Newton, Billy W., Urbanowski, Matthew, Kim, Heejin, Williams, Michael A. P., Rezelj, Veronica V., Hardy, Alexandra, Fossati, Andrea, Stevenson, Erica J., Sukerman, Ellie, Kim, Tiffany, Penugonda, Sudhir, Moreno, Elena, Braberg, Hannes, Zhou, Yuan, Metreveli, Giorgi, Harjai, Bhavya, Tummino, Tia A., Melnyk, James E., Soucheray, Margaret, Batra, Jyoti, Pache, Lars, Martin-Sancho, Laura, Carlson-Stevermer, Jared, Jureka, Alexander S., Basler, Christopher F., Shokat, Kevan M., Shoichet, Brian K., Shriver, Leah P., Johnson, Jeffrey R., Shaw, Megan L., Chanda, Sumit K., Roden, Dan M., Carter, Tonia C., Kottyan, Leah C., Chisholm, Rex L., Pacheco, Jennifer A., Smith, Maureen E., Schrodi, Steven J., Albrecht, Randy A., Vignuzzi, Marco, Zuliani-Alvarez, Lorena, Swaney, Danielle L., Eckhardt, Manon, Wolinsky, Steven M., White, Kris M., Hultquist, Judd F., Kaake, Robyn M., García-Sastre, Adolfo, Krogan, Nevan J.

“…Influenza A Virus (IAV) is a recurring respiratory virus with limited availability of antiviral therapies. Understanding host proteins essential for IAV…”
Get full text

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms by Gordon, David E, Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V, Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S, Obernier, Kirsten, Guo, Jeffrey Z, Batra, Jyoti, Kaake, Robyn M, Weckstein, Andrew R, Owens, Tristan W, Gupta, Meghna, Pourmal, Sergei, Titus, Erron W, Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O'Meara, Matthew J, Tummino, Tia A, Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L, Fabius, Jacqueline M, Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M, Naing, Zun Zar Chi, Pulido, Ernst H, Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A, Azumaya, Caleigh M, Billesbølle, Christian, Brilot, Axel F, Campbell, Melody G, Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T, Liu, Yanxin, Merz, Gregory E, Moritz, Michelle, Nguyen, Henry C, Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N, Schulze-Gahmen, Ursula, Smith, Amber M, Sun, Ming, Young, Iris D, Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R, Chen, Jen, Chio, Cynthia M, Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L, Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E, Melo, Arthur A, Moss, 3rd, Frank R, Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K

“…The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a grave threat to public health and the global economy…”
Get full text

ABANDONED IMAGES: FILM AND FILM'S END by Haas, Kelsey

“…There have been several books published in recent years on the topic of the power struggle between film and digital technologies such as Paolo Cherchi Usai's…”
Get full text