Tuberculosis drug resistance and HIV infection, the Netherlands

In the Netherlands during 1993-2001, multidrug-resistant tuberculosis among newly diagnosed patients was more frequent in those with HIV coinfection (5/308, 1.6%) than in those with no HIV infection (39/646, 0.6%; adjusted odds ratio 3.43, p=0.015). Four of the 5 patients coinfected with multidrug-r...

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Bibliographic Details
Published in:	Emerging infectious diseases Vol. 13; no. 5; pp. 776 - 778
Main Authors:	Haar, Catharina Hendrika, Cobelens, Frank G J, Kalisvaart, Nico A, van der Have, Jan J, van Gerven, Paul J H J, van Soolingen, Dick
Format:	Journal Article
Language:	English
Published:	United States U.S. National Center for Infectious Diseases 01-05-2007 Centers for Disease Control and Prevention
Subjects:	Adult Analysis Antitubercular Agents Disease transmission Dispatch DNA Fingerprinting Drug resistance Drug therapy Emigrants and Immigrants Female Health aspects HIV HIV (Viruses) HIV infection HIV Infections - complications Human immunodeficiency virus Humans Male multidrug resistance Mycobacterium Mycobacterium tuberculosis - classification Mycobacterium tuberculosis - genetics Netherlands - epidemiology Prevalence Registries the Netherlands Tuberculosis Tuberculosis, Multidrug-Resistant - complications Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - epidemiology Tuberculosis, Multidrug-Resistant - transmission Netherlands
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Summary:	In the Netherlands during 1993-2001, multidrug-resistant tuberculosis among newly diagnosed patients was more frequent in those with HIV coinfection (5/308, 1.6%) than in those with no HIV infection (39/646, 0.6%; adjusted odds ratio 3.43, p=0.015). Four of the 5 patients coinfected with multidrug-resistant tuberculosis and HIV were foreign-born. DNA fingerprint analysis suggested that transmission had occurred outside the Netherlands.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1305.060334