Search Results - "Haagmans, Bart"

SARS-CoV-2 pathogenesis by Lamers, Mart M., Haagmans, Bart L.

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating pandemic. Although most people infected with SARS-CoV-2…”
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Assessing the extent of SARS-CoV-2 circulation through serological studies by Koopmans, Marion, Haagmans, Bart

“…The COVID-19 pandemic has highlighted the crucial importance of antibody surveys in estimating the incidence of SARS-CoV-2 infection at a population level…”
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The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology by Oude Munnink, Bas B., Worp, Nathalie, Nieuwenhuijse, David F., Sikkema, Reina S., Haagmans, Bart, Fouchier, Ron A. M., Koopmans, Marion

“…The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-genome sequencing near to real time, with over 2 million severe acute…”
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Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner by Burkard, Christine, Verheije, Monique H, Wicht, Oliver, van Kasteren, Sander I, van Kuppeveld, Frank J, Haagmans, Bart L, Pelkmans, Lucas, Rottier, Peter J M, Bosch, Berend Jan, de Haan, Cornelis A M

“…Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome into the host cell. While some viruses fuse with the plasma membrane,…”
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A human monoclonal antibody blocking SARS-CoV-2 infection by Wang, Chunyan, Li, Wentao, Drabek, Dubravka, Okba, Nisreen M. A., van Haperen, Rien, Osterhaus, Albert D. M. E., van Kuppeveld, Frank J. M., Haagmans, Bart L., Grosveld, Frank, Bosch, Berend-Jan

“…The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and…”
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Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model by Rockx, Barry, Kuiken, Thijs, Herfst, Sander, Bestebroer, Theo, Lamers, Mart M, Oude Munnink, Bas B, de Meulder, Dennis, van Amerongen, Geert, van den Brand, Judith, Okba, Nisreen M A, Schipper, Debby, van Run, Peter, Leijten, Lonneke, Sikkema, Reina, Verschoor, Ernst, Verstrepen, Babs, Bogers, Willy, Langermans, Jan, Drosten, Christian, Fentener van Vlissingen, Martje, Fouchier, Ron, de Swart, Rik, Koopmans, Marion, Haagmans, Bart L

“…The current pandemic coronavirus, severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), was recently identified in patients with an acute respiratory…”
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Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein by Li, Wentao, Hulswit, Ruben J. G., Widjaja, Ivy, Raj, V. Stalin, McBride, Ryan, Peng, Wenjie, Widagdo, W., Tortorici, M. Alejandra, van Dieren, Brenda, Lang, Yifei, van Lent, Jan W. M., Paulson, James C., de Haan, Cornelis A. M., de Groot, Raoul J., van Kuppeveld, Frank J. M., Haagmans, Bart L., Bosch, Berend-Jan

“…Middle East respiratory syndrome coronavirus (MERS-CoV) targets the epithelial cells of the respiratory tract both in humans and in its natural host, the…”
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Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR by Corman, Victor M, Landt, Olfert, Kaiser, Marco, Molenkamp, Richard, Meijer, Adam, Chu, Daniel Kw, Bleicker, Tobias, Brünink, Sebastian, Schneider, Julia, Schmidt, Marie Luisa, Mulders, Daphne Gjc, Haagmans, Bart L, van der Veer, Bas, van den Brink, Sharon, Wijsman, Lisa, Goderski, Gabriel, Romette, Jean-Louis, Ellis, Joanna, Zambon, Maria, Peiris, Malik, Goossens, Herman, Reusken, Chantal, Koopmans, Marion Pg, Drosten, Christian

“…The ongoing outbreak of the recently emerged novel coronavirus (2019-nCoV) poses a challenge for public health laboratories as virus isolates are unavailable…”
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SARS-CoV-2 Omicron variant is highly sensitive to molnupiravir, nirmatrelvir, and the combination by Li, Pengfei, Wang, Yining, Lavrijsen, Marla, Lamers, Mart M., de Vries, Annemarie C., Rottier, Robbert J., Bruno, Marco J., Peppelenbosch, Maikel P., Haagmans, Bart L., Pan, Qiuwei

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SARS-CoV-2 productively infects human gut enterocytes by Lamers, Mart M, Beumer, Joep, van der Vaart, Jelte, Knoops, Kèvin, Puschhof, Jens, Breugem, Tim I, Ravelli, Raimond B G, Paul van Schayck, J, Mykytyn, Anna Z, Duimel, Hans Q, van Donselaar, Elly, Riesebosch, Samra, Kuijpers, Helma J H, Schipper, Debby, van de Wetering, Willine J, de Graaf, Miranda, Koopmans, Marion, Cuppen, Edwin, Peters, Peter J, Haagmans, Bart L, Clevers, Hans

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause coronavirus disease 2019 (COVID-19), an influenza-like disease that is primarily thought…”
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Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease Patients by Okba, Nisreen M A, Müller, Marcel A, Li, Wentao, Wang, Chunyan, GeurtsvanKessel, Corine H, Corman, Victor M, Lamers, Mart M, Sikkema, Reina S, de Bruin, Erwin, Chandler, Felicity D, Yazdanpanah, Yazdan, Le Hingrat, Quentin, Descamps, Diane, Houhou-Fidouh, Nadhira, Reusken, Chantal B E M, Bosch, Berend-Jan, Drosten, Christian, Koopmans, Marion P G, Haagmans, Bart L

“…A new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently emerged to cause a human pandemic. Although molecular diagnostic…”
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Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability by Brouwer, Philip J M, Caniels, Tom G, van der Straten, Karlijn, Snitselaar, Jonne L, Aldon, Yoann, Bangaru, Sandhya, Torres, Jonathan L, Okba, Nisreen M A, Claireaux, Mathieu, Kerster, Gius, Bentlage, Arthur E H, van Haaren, Marlies M, Guerra, Denise, Burger, Judith A, Schermer, Edith E, Verheul, Kirsten D, van der Velde, Niels, van der Kooi, Alex, van Schooten, Jelle, van Breemen, Mariëlle J, Bijl, Tom P L, Sliepen, Kwinten, Aartse, Aafke, Derking, Ronald, Bontjer, Ilja, Kootstra, Neeltje A, Wiersinga, W Joost, Vidarsson, Gestur, Haagmans, Bart L, Ward, Andrew B, de Bree, Godelieve J, Sanders, Rogier W, van Gils, Marit J

“…The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a large impact on global health, travel, and economy. Therefore,…”
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ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity by Lamers, Mart M, van den Hoogen, Bernadette G, Haagmans, Bart L

“…Specialized receptors that recognize molecular patterns such as double stranded RNA duplexes-indicative of viral replication-are potent triggers of the innate…”
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SARS-CoV-2 is transmitted via contact and via the air between ferrets by Richard, Mathilde, Kok, Adinda, de Meulder, Dennis, Bestebroer, Theo M., Lamers, Mart M., Okba, Nisreen M. A., Fentener van Vlissingen, Martje, Rockx, Barry, Haagmans, Bart L., Koopmans, Marion P. G., Fouchier, Ron A. M., Herfst, Sander

“…SARS-CoV-2, a coronavirus that emerged in late 2019, has spread rapidly worldwide, and information about the modes of transmission of SARS-CoV-2 among humans…”
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An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment by GeurtsvanKessel, Corine H., Okba, Nisreen M. A., Igloi, Zsofia, Bogers, Susanne, Embregts, Carmen W. E., Laksono, Brigitta M., Leijten, Lonneke, Rokx, Casper, Rijnders, Bart, Rahamat-Langendoen, Janette, van den Akker, Johannes P. C., van Kampen, Jeroen J. A., van der Eijk, Annemiek A., van Binnendijk, Rob S., Haagmans, Bart, Koopmans, Marion

“…The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the…”
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Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19) by van Kampen, Jeroen J. A., van de Vijver, David A. M. C., Fraaij, Pieter L. A., Haagmans, Bart L., Lamers, Mart M., Okba, Nisreen, van den Akker, Johannes P. C., Endeman, Henrik, Gommers, Diederik A. M. P. J., Cornelissen, Jan J., Hoek, Rogier A. S., van der Eerden, Menno M., Hesselink, Dennis A., Metselaar, Herold J., Verbon, Annelies, de Steenwinkel, Jurriaan E. M., Aron, Georgina I., van Gorp, Eric C. M., van Boheemen, Sander, Voermans, Jolanda C., Boucher, Charles A. B., Molenkamp, Richard, Koopmans, Marion P. G., Geurtsvankessel, Corine, van der Eijk, Annemiek A.

“…Key questions in COVID-19 are the duration and determinants of infectious virus shedding. Here, we report that infectious virus shedding is detected by virus…”
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Glycosylated extracellular mucin domains protect against SARS-CoV-2 infection at the respiratory surface by Chatterjee, Maitrayee, Huang, Liane Z X, Mykytyn, Anna Z, Wang, Chunyan, Lamers, Mart M, Westendorp, Bart, Wubbolts, Richard W, van Putten, Jos P M, Bosch, Berend-Jan, Haagmans, Bart L, Strijbis, Karin

“…Mucins play an essential role in protecting the respiratory tract against microbial infections while also acting as binding sites for bacterial and viral…”
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Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection by Brouwer, Philip J.M., Brinkkemper, Mitch, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Grobben, Marloes, Claireaux, Mathieu, de Gast, Marlon, Marlin, Romain, Chesnais, Virginie, Diry, Ségolène, Allen, Joel D., Watanabe, Yasunori, Giezen, Julia M., Kerster, Gius, Turner, Hannah L., van der Straten, Karlijn, van der Linden, Cynthia A., Aldon, Yoann, Naninck, Thibaut, Bontjer, Ilja, Burger, Judith A., Poniman, Meliawati, Mykytyn, Anna Z., Okba, Nisreen M.A., Schermer, Edith E., van Breemen, Marielle J., Ravichandran, Rashmi, Caniels, Tom G., van Schooten, Jelle, Kahlaoui, Nidhal, Contreras, Vanessa, Lemaître, Julien, Chapon, Catherine, Fang, Raphaël Ho Tsong, Villaudy, Julien, Sliepen, Kwinten, van der Velden, Yme U., Haagmans, Bart L., de Bree, Godelieve J., Ginoux, Eric, Ward, Andrew B., Crispin, Max, King, Neil P., van der Werf, Sylvie, van Gils, Marit J., Le Grand, Roger, Sanders, Rogier W.

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is continuing to disrupt personal lives, global healthcare systems, and economies…”
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Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets by de Vries, Rory D, Schmitz, Katharina S, Bovier, Francesca T, Predella, Camilla, Khao, Jonathan, Noack, Danny, Haagmans, Bart L, Herfst, Sander, Stearns, Kyle N, Drew-Bear, Jennifer, Biswas, Sudipta, Rockx, Barry, McGill, Gaël, Dorrello, N Valerio, Gellman, Samuel H, Alabi, Christopher A, de Swart, Rik L, Moscona, Anne, Porotto, Matteo

“…Containment of the COVID-19 pandemic requires reducing viral transmission. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is initiated…”
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Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens by Bezstarosti, Karel, Lamers, Mart M, Doff, Wouter A. S, Wever, Peter C, Thai, Khoa T. D, van Kampen, Jeroen J. A, Haagmans, Bart L, Demmers, Jeroen A. A

“…The rapid, sensitive and specific detection of SARS-CoV-2 is critical in responding to the current COVID-19 outbreak. In this proof-of-concept study, we…”
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