Search Results - "Hála, Ottó"
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1
Role of IKur in controlling action potential shape and contractility in the human atrium: Influence of chronic atrial fibrillation
Published in Circulation (New York, N.Y.) (19-10-2004)“…The ultrarapid outward current I(Kur) is a major repolarizing current in human atrium and a potential target for treating atrial arrhythmias. The effects of…”
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2
Self‐augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency
Published in British journal of pharmacology (01-04-2009)“…Background and purpose: The aims of the present work were to study the mechanism of the reverse rate dependency of different interventions prolonging cardiac…”
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3
Theoretical possibilities for the development of novel antiarrhythmic drugs
Published in Current medicinal chemistry (01-01-2004)“…One possible mechanism of action of the available K-channel blocking agents used to treat arrhythmias is to selectively inhibit the HERG plus MIRP channels,…”
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4
Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone
Published in British journal of pharmacology (01-07-2001)“…The electrophysiological effects of dronedarone, a new nonionidated analogue of amiodarone were studied after chronic and acute administration in dog Purkinje…”
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Journal Article -
5
Role of I Kur in Controlling Action Potential Shape and Contractility in the Human Atrium: Influence of Chronic Atrial Fibrillation
Published in Circulation (New York, N.Y.) (19-10-2004)“…Background— The ultrarapid outward current I Kur is a major repolarizing current in human atrium and a potential target for treating atrial arrhythmias. The…”
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Journal Article -
6
Pharmacological modulation of ion channels and transporters
Published in Cell calcium (Edinburgh) (01-06-2004)“…Ion channels and transporter proteins are prerequisites for formation and conduction of cardiac electrical impulses. Acting in concert, these proteins maintain…”
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Journal Article -
7
Analysis of Mode of Action of Antiarrhythmics in Isolated Cardiac Preparations: The Ultrarapid Delayed Rectifier K+Current as Potential Target for Treatment of Human Atrial Fibrillation
Published 01-01-2003“…Therapeutical ImplicationsWe have seen that by inhibition of the atrial specific IKur current, antiarrhythmic/antifibrillatory effects can be expected in…”
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Dissertation -
8
The cellular electrophysiological effects of tedisamil in human atrial and ventricular fibers
Published in Cardiovascular research (01-02-1996)“…The cellular electrophysiological effects of 1 microM tedisamil (KC 8857) were studied in human atrial and ventricular fibers. Conventional microelectrode…”
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9
The cellular electrophysiological effects of tedisamil in human atrial and ventricular fibers
Published in Cardiovascular research (01-02-1996)“…The cellular electrophysiological effects of 1 μM tedisamil (KC 8857) were studied in human atrial and ventricular fibers. Conventional microelectrode…”
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Journal Article -
10
Electrophysiologic effects of detajmium on isolated dog cardiac ventricular and Purkinje fibers
Published in Journal of cardiovascular pharmacology (01-10-1994)“…We studied the electrophysiologic effects of the antiarrhythmic compound detajmium (Tachmalcor) on isolated dog and rabbit cardiac preparations, applying the…”
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11
Antiaritmiás Szerek Elektrofarmakológiai Hatásainak Számítógépes Elemzése
Published 01-01-1992“…Az értekezés témájának megválasztása igen könnyű, - de egyben igen nehéz feladatot is jelentett. Egyrészről nem volt kétséges, hogy a tartalom gerincét a napi…”
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Dissertation -
12
Cardiac electrophysiological effects of levosimendan, a new calcium sensitizer
Published in General pharmacology (01-04-1996)“…1. 1. The conventional microelectrode and the patch-clamp techniques were used to study the electrophysiological effects of levosimendan, a new…”
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Journal Article