Search Results - "Ha, Sang Eun"
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Scutellarein Induces Fas-Mediated Extrinsic Apoptosis and G2/M Cell Cycle Arrest in Hep3B Hepatocellular Carcinoma Cells
Published in Nutrients (24-01-2019)“…Scutellarein (SCU), a flavone found in the perennial herb , is known for a wide range of biological activities. In the present study, we investigated the…”
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Iridin Induces G2/M Phase Cell Cycle Arrest and Extrinsic Apoptotic Cell Death through PI3K/AKT Signaling Pathway in AGS Gastric Cancer Cells
Published in Molecules (Basel, Switzerland) (10-05-2021)“…Iridin is a natural flavonoid found in documented for its broad spectrum of biological activities like antioxidant, antitumor, and antiproliferative effects…”
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Apigetrin Abrogates Lipopolysaccharide-Induced Inflammation in L6 Skeletal Muscle Cells through NF-κB/MAPK Signaling Pathways
Published in Current issues in molecular biology (08-06-2022)“…Apigetrin is a glycosidic flavonoid derived from Teucrium gnaphalodes that has a wide range of biological activities, including antioxidant, anti-inflammatory,…”
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Apigetrin induces extrinsic apoptosis, autophagy and G2/M phase cell cycle arrest through PI3K/AKT/mTOR pathway in AGS human gastric cancer cell
Published in The Journal of nutritional biochemistry (01-09-2020)“…Apigetrin is a flavonoid glycoside phytonutrient derived from fruits and vegetables that is well known for a variety of biological activities such as…”
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Scutellarein Inhibits LPS-Induced Inflammation through NF-κB/MAPKs Signaling Pathway in RAW264.7 Cells
Published in Molecules (Basel, Switzerland) (12-06-2022)“…Inflammation is a severe topic in the immune system and play a role as pro-inflammatory mediators. In response to such inflammatory substances, immune cells…”
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Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway
Published in Nutrients (08-08-2018)“…Pectolinarigenin (PEC), a natural flavonoid present in and in some species of fruits, has various pharmacological benefits such as anti-inflammatory and…”
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Inhibition of Cell Proliferation and Metastasis by Scutellarein Regulating PI3K/Akt/NF-κB Signaling through PTEN Activation in Hepatocellular Carcinoma
Published in International journal of molecular sciences (17-08-2021)“…Scutellarein (SCU) is a well-known flavone with a broad range of biological activities against several cancers. Human hepatocellular carcinoma (HCC) is major…”
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Flavones: Six Selected Flavones and Their Related Signaling Pathways That Induce Apoptosis in Cancer
Published in International journal of molecular sciences (19-09-2022)“…Cancer is a horrific disease that, to date, has no cure. It is caused by various factors and takes many lives. Apoptosis is a programmed cell death mechanism…”
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Potential Antioxidant and Anti-Inflammatory Function of Gynura procumbens Polyphenols Ligand
Published in International journal of molecular sciences (13-08-2021)“…The antioxidant and anti-inflammatory potentials of polyphenols contained in Gynura procumbens (GP) extract were systematically analyzed. Polyphenols in GP…”
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Sinensetin Induces Autophagic Cell Death through p53-Related AMPK/mTOR Signaling in Hepatocellular Carcinoma HepG2 Cells
Published in Nutrients (15-08-2020)“…Sinensetin (SIN) has been reported to exhibit anti-inflammatory and anti-cancer activity. However, the cellular and molecular mechanism by which SIN promotes…”
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Function and Application of Flavonoids in the Breast Cancer
Published in International journal of molecular sciences (13-07-2022)“…Breast cancer is one of the top causes of death, particularly among women, and it affects many women. Cancer can also be caused by various factors, including…”
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Investigation on the cellular mechanism of Prunetin evidenced through next generation sequencing and bioinformatic approaches against gastric cancer
Published in Scientific reports (13-07-2022)“…Gastric cancer is the common type of malignancy positioned at second in mortality rate causing burden worldwide with increasing treatment options. More…”
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Cellular Regulation of Kynurenic Acid-Induced Cell Apoptosis Pathways in AGS Cells
Published in International journal of molecular sciences (10-08-2022)“…Kynurenic acid was included in the three compounds (caffeic acid, chlorogenic acid, and kynurenic acid) that showed high antioxidant and anti-inflammatory…”
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Prunetinoside Inhibits Lipopolysaccharide-Provoked Inflammatory Response via Suppressing NF-κB and Activating the JNK-Mediated Signaling Pathway in RAW264.7 Macrophage Cells
Published in International journal of molecular sciences (13-05-2022)“…Inflammation is a multifaceted response of the immune system at the site of injury or infection caused by pathogens or stress via immune cells. Due to the…”
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Compound Prunetin Induces Cell Death in Gastric Cancer Cell with Potent Anti-Proliferative Properties: In Vitro Assay, Molecular Docking, Dynamics, and ADMET Studies
Published in Biomolecules (Basel, Switzerland) (21-07-2020)“…Gastric cancer is the common type of malignancy positioned at second in mortality rate causing burden worldwide with increasing treatment options. Prunetin…”
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Identification of Kynurenic Acid-Induced Apoptotic Biomarkers in Gastric Cancer-Derived AGS Cells through Next-Generation Transcriptome Sequencing Analysis
Published in Nutrients (30-12-2022)“…Understanding the triggers and therapeutic targets for gastric cancer, one of the most common cancers worldwide, can provide helpful information for the…”
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Apigetrin Promotes TNFα-Induced Apoptosis, Necroptosis, G2/M Phase Cell Cycle Arrest, and ROS Generation through Inhibition of NF-κB Pathway in Hep3B Liver Cancer Cells
Published in Cells (Basel, Switzerland) (01-09-2022)“…Apigetrin (7-(β-D-glucopyranosyloxy)-4′,5-dihydroxyflavone), a glycoside bioactive dietary flavonoid derived from Taraxacum officinale and Teucrium…”
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Cellular Function of Annexin A1 Protein Mimetic Peptide Ac2-26 in Human Skin Keratinocytes HaCaT and Fibroblast Detroit 551 Cells
Published in Nutrients (24-10-2020)“…Inflammation of the skin is the most common dermatological problem in human. The anti-inflammatory mediated responses of the skin cells provide a mechanism for…”
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Comparative Proteomic Profiling of Tumor-Associated Proteins in Human Gastric Cancer Cells Treated with Pectolinarigenin
Published in Nutrients (30-10-2018)“…Pectolinarigenin (PEC), a natural flavonoid that is present in citrus fruits, has been reported to exhibit antitumor effects in several cancers. Though the…”
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Quantitative Proteomics Analysis for the Identification of Differential Protein Expression in Calf Muscles between Young and Old SD Rats Using Mass Spectrometry
Published in ACS omega (23-03-2021)“…Aging is associated with loss of muscle mass and strength that leads to a condition termed sarcopenia. Impaired conditions, morbidity, and malnutrition are the…”
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