Search Results - "Ha, Kyungsik"
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Hybrid Stomach-Intestinal Chromatin States Underlie Human Barrett’s Metaplasia
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2021)“…Tissue metaplasia is uncommon in adults because established cis-element programs resist rewiring. In Barrett’s esophagus, the distal esophageal mucosa acquires…”
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COOBoostR: An Extreme Gradient Boosting-Based Tool for Robust Tissue or Cell-of-Origin Prediction of Tumors
Published in Life (Basel, Switzerland) (27-12-2022)“…We present here COOBoostR, a computational method designed for the putative prediction of the tissue- or cell-of-origin of various cancer types. COOBoostR…”
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Chromatin marks shape mutation landscape at early stage of cancer progression
Published in Npj genomic medicine (03-04-2017)“…Somatic mutation rates in cancer differ across the genome in a cancer cell-type specific manner. Although key factors that contribute to the differences were…”
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Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancer
Published in Heliyon (01-02-2020)“…Primary liver tissue cancer types are renowned to display a consistent increase in global disease burden and mortality, thus needing more effective diagnostics…”
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An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping
Published in Cell (25-11-2020)“…Gastroenteropancreatic (GEP) neuroendocrine neoplasm (NEN) that consists of neuroendocrine tumor and neuroendocrine carcinoma (NEC) is a lethal but…”
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Simulation of annealing process on AISI 316 L stainless steel fabricated via laser powder bed fusion using finite element method with creep
Published in Additive manufacturing (01-12-2022)“…In the laser powder bed fusion (L-PBF) process, the development of residual stress in as-built components is unavoidable owing to the concentrated heat input…”
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Biomedical Entity Explorer: A Web Server for Biomedical Entity Exploration
Published in Journal of computational biology (01-06-2021)“…Biomedical Entity Explorer (BEE) is a web server that can search for biomedical entities from a database of six biomedical entity types (gene, miRNA, drug,…”
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Abstract 6054: UPPGRADER: a bioinformatics-based novel E3 ligase discovery platform
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract In Target Protein Degradation (TPD) field, conventional E3 ligases utilized in the clinic are limited to CRBN and VHL, which opens the need for…”
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Abstract 2727: The premalignant state captured in the landscape of somatic mutations can reveal the cancer cell-of-origin
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Despite increasing knowledge of tumorigenesis, the identity of the cancer cell-of-origin, i.e. the normal cell type that acquired the…”
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Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinoma
Published in EBioMedicine (01-06-2023)“…Birt-Hogg-Dubé (BHD) syndrome, caused by germline alteration of folliculin (FLCN) gene, develops hybrid oncocytic/chromophobe tumour (HOCT) and chromophobe…”
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Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinomaResearch in context
Published in EBioMedicine (01-06-2023)“…Background: Birt-Hogg-Dubé (BHD) syndrome, caused by germline alteration of folliculin (FLCN) gene, develops hybrid oncocytic/chromophobe tumour (HOCT) and…”
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5-21-14 A case of ophthalmoplegic migraine; Reversible ischemia demonstrated by brain SPECT
Published in Journal of the neurological sciences (01-09-1997)Get full text
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