Search Results - "Ha, Junkyu"
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Brain‐targeted exosome‐mimetic cell membrane nanovesicles with therapeutic oligonucleotides elicit anti‐tumor effects in glioblastoma animal models
Published in Bioengineering & translational medicine (01-03-2023)“…The brain‐targeted delivery of therapeutic oligonucleotides has been investigated as a new treatment modality for various brain diseases, such as brain tumors…”
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Antisense-oligonucleotide co-micelles with tumor targeting peptides elicit therapeutic effects by inhibiting microRNA-21 in the glioblastoma animal models
Published in Journal of advanced research (01-11-2023)“…[Display omitted] •Co-micelles were produced with cholesterol-conjugated anti-microRNA-21 oligonucleotides (AMO21c) and cholesterol-conjugated T7 peptides…”
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Engineering exosomes for pulmonary delivery of peptides and drugs to inflammatory lung cells by inhalation
Published in Journal of controlled release (10-02-2021)“…Exosomes have been investigated as delivery vesicles for various drugs. However, exosome-mediated peptide delivery into the lungs has not been studied. In this…”
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A RAGE-antagonist peptide potentiates polymeric micelle-mediated intracellular delivery of plasmid DNA for acute lung injury gene therapy
Published in Nanoscale (02-07-2020)“…Acute lung injury (ALI) is a severe inflammatory lung disease. A high mobility group box-1 (HMGB-1) derived RAGE-antagonist peptide (RAP) was previously…”
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Delivery of MiRNA-92a Inhibitor Using RP1-Linked Peptide Elicits Anti-Inflammatory Effects in an Acute Lung Injury Model
Published in Journal of biomedical nanotechnology (01-07-2021)“…Acute lung injury (ALI) is an inflammatory lung disease. miRNA-92a (miR92a) is induced in the lungs of ALI patients and mediates inflammatory reactions. In…”
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Inhalable Gene Delivery System Using a Cationic RAGE-Antagonist Peptide for Gene Delivery to Inflammatory Lung Cells
Published in ACS biomaterials science & engineering (13-05-2019)“…Acute lung injury (ALI) is a severe lung inflammatory disease. In ALI, the receptor for advanced glycation end-products (RAGE) is overexpressed in lung…”
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