Search Results - "Ha, Jun Yong"

Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface by Lee, Hyung Ho, Kim, Hyoun Sook, Kang, Ji Yong, Lee, Byung Il, Ha, Jun Yong, Yoon, Hye Jin, Lim, Seung Oe, Jung, Guhung, Suh, Se Won

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Crystal Structure of Agmatinase Reveals Structural Conservation and Inhibition Mechanism of the Ureohydrolase Superfamily by Ahn, Hyung Jun, Kim, Kyoung Hoon, Lee, Jiah, Ha, Jun-Yong, Lee, Hyung Ho, Kim, Dojin, Yoon, Hye-Jin, Kwon, Ae-Ran, Suh, Se Won

“…Agmatine is the product of arginine decarboxylation and can be hydrolyzed by agmatinase to putrescine, the precursor for biosynthesis of higher polyamines,…”
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Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region by Yu, Jong W, Jeffrey, Philip D, Ha, Jun Yong, Yang, Xiaolu, Shi, Yigong

“…The mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase, a key component of the Carma1/Bcl10/MALT1 signalosome, is critical for…”
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Cog5–Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex by Ha, Jun Yong, Pokrovskaya, Irina D., Climer, Leslie K., Shimamura, Gregory R., Kudlyk, Tetyana, Jeffrey, Philip D., Lupashin, Vladimir V., Hughson, Frederick M.

“…Significance In all eukaryotes, the docking and fusion of the vesicles that mediate intracellular trafficking requires multisubunit tethering complexes (MTCs)…”
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Crystal Structure of a Metal Ion-bound IS200 Transposase by Lee, Hyung Ho, Yoon, Ji Young, Kim, Hyoun Sook, Kang, Ji Yong, Kim, Kyoung Hoon, Kim, Do Jin, Ha, Jun Yong, Mikami, Bunzo, Yoon, Hye Jin, Suh, Se Won

“…IS200 transposases, present in many bacteria and Archaea, appear to be distinct from other groups of transposases. To provide a structural basis for…”
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Arrest Defective 1 Autoacetylation Is a Critical Step in Its Ability to Stimulate Cancer Cell Proliferation by JI HAE SEO, CHA, Jong-Ho, JUN YONG HA, SANG HEE HAN, KIM, Se-Hee, LEE, Ji-Won, JEONG AE PARK, JEONG, Joo-Won, LEE, Kong-Joo, GOO TAEG OH, LEE, Mi-Ni, SUNG WON KWON, PARK, Ji-Hyeon, LEE, Seung-Ki, CHUN, Kwang-Hoon, LEE, Su-Jae, KIM, Kyu-Won, JEONG, Chul-Ho, PARK, Zee-Yong, LEE, Hye-Suk, SEUNG HYUN OH, KANG, Ju-Hee, SE WON SUH, KYOUNG HOON KIM

“…The N-acetyltransferase arrest defective 1 (ARD1) is an important regulator of cell growth and differentiation that has emerged recently as a critical molecule…”
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Crystal structure of 2-nitropropane dioxygenase complexed with FMN and substrate. Identification of the catalytic base by Ha, Jun Yong, Min, Ji Young, Lee, Su Kyung, Kim, Hyoun Sook, Kim, Do Jin, Kim, Kyoung Hoon, Lee, Hyung Ho, Kim, Hye Kyung, Yoon, Hye-Jin, Suh, Se Won

“…Nitroalkane compounds are widely used in chemical industry and are also produced by microorganisms and plants. Some nitroalkanes have been demonstrated to be…”
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Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase by Kim, Kyoung Hoon, Ahn, Hyung Jun, Kim, Do Jin, Lee, Hyung Ho, Ha, Jun-Yong, Kim, Hye-Kyung, Yoon, Hye-Jin, Suh, Se Won

“…Agmatine, which results from the decarboxylation of l‐arginine by arginine decarboxylase, is a metabolic intermediate in the biosynthesis of putresine and…”
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Crystal structure of T-protein of the glycine cleavage system. Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia by Lee, Hyung Ho, Kim, Do Jin, Ahn, Hyung Jun, Ha, Jun Yong, Suh, Se Won

“…The glycine cleavage system catalyzes the oxidative decarboxylation of glycine in bacteria and in mitochondria of animals and plants. Its deficiency in human…”
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recombination-associated protein RdgC adopts a novel toroidal architecture for DNA binding by Ha, Jun Yong, Kim, Hye Kyong, Kim, Do Jin, Kim, Kyoung Hoon, Oh, Sung Jin, Lee, Hyung Ho, Yoon, Hye Jin, Song, Hyun Kyu, Suh, Se Won

“…RecA plays a central role in the nonmutagenic repair of stalled replication forks in bacteria. RdgC, a recombination-associated DNA-binding protein, is a…”
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Crystal Structure of 2-Nitropropane Dioxygenase Complexed with FMN and Substrate by Ha, Jun Yong, Min, Ji Young, Lee, Su Kyung, Kim, Hyoun Sook, Kim, Do Jin, Kim, Kyoung Hoon, Lee, Hyung Ho, Kim, Hye Kyung, Yoon, Hye-Jin, Suh, Se Won

“…Nitroalkane compounds are widely used in chemical industry and are also produced by microorganisms and plants. Some nitroalkanes have been demonstrated to be…”
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2,3-Diarylpyran-4-ones: a new series of selective cyclooxygenase-2 inhibitors by YUNG HYUP JOO, JIN KWAN KIM, KANG, Seon-Hwa, NOH, Min-Soo, HA, Jun-Yong, JIN KYU CHOI, KYUNG MIN LIM, CHUNG, Shin

“…A new series of cyclooxygenase-2 (COX-2) inhibitors with gamma-pyrone as central scaffold unit has been synthesized and their biological activities were…”
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Crystal Structure of T-protein of the Glycine Cleavage System by Lee, Hyung Ho, Kim, Do Jin, Ahn, Hyung Jun, Ha, Jun Yong, Suh, Se Won

“…The glycine cleavage system catalyzes the oxidative decarboxylation of glycine in bacteria and in mitochondria of animals and plants. Its deficiency in human…”
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Crystal Structure of Lipoate-Protein Ligase A Bound with the Activated Intermediate by Kim, Do Jin, Kim, Kyoung Hoon, Lee, Hyung Ho, Lee, Sang Jae, Ha, Jun Yong, Yoon, Hye Jin, Suh, Se Won

“…Lipoic acid is the covalently attached cofactor of several multi-component enzyme complexes that catalyze key metabolic reactions. Attachment of lipoic acid to…”
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2,3-Diarylbenzopyran derivatives as a novel class of selective cyclooxygenase-2 inhibitors by Hyup Joo, Yung, Kwan Kim, Jin, Kang, Seon-Hwa, Noh, Min-Soo, Ha, Jun-Yong, Kyu Choi, Jin, Min Lim, Kyung, Hoon Lee, Chang, Chung, Shin

“…A new series of cyclooxygenase-2(COX-2) inhibitors with naturally occurring flavone as the main skeleton has been synthesized and their biological activities…”
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Molecular architecture of the complete COG tethering complex by Ha, Jun Yong, Chou, Hui-Ting, Ungar, Daniel, Yip, Calvin K, Walz, Thomas, Hughson, Frederick M

“…The complete architecture of the yeast COG tethering complex is revealed by negative-stain electron microscopy, showing an intricate shape with up to five…”
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Crystallization and preliminary X-ray crystallographic analysis of a putative agmatinase from Deinococcus radiodurans by Lee, Ji Ah, Ahn, Hyung Jun, Ha, Jun Yong, Shim, Sun Mi, Kim, Kyoung Hoon, Kim, Hye Kyung, Suh, Se Won

“…Agmatine, which results from the decarboxylation of arginine by arginine decarboxylase, is a metabolic intermediate in the biosynthesis of putresine and higher…”
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Crystallization and preliminary X-ray crystallographic analysis of the RecR protein from Deinococcus radiodurans, a member of the RecFOR DNA-repair pathway by Lee, Byung Il, Kim, Kyoung Hoon, Shim, Sun Mi, Ha, Kyung Soo, Yang, Jin Kuk, Yoon, Hye-Jin, Ha, Jun Yong, Suh, Se Won

“…The RecR protein plays a key role in the RecFOR pathway of recombination, which is necessary for the repair of ssDNA gaps. RecR from Deinococcus radiodurans…”
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X-ray crystallographic studies of HemK from Thermotoga maritima, an N5-glutamine methyltransferase by Yoon, Hye-Jin, Kang, Kyung Yi, Ahn, Hyung Jun, Shim, Sun Mi, Ha, Jun-Yong, Lee, Soo-Kyoung, Mikami, Bunzo, Suh, Se Won

“…The enzyme HemK (or PrmC) is one of the first identified methyltransferases that modify glutamine. It methylates the highly conserved GGQ motif in class I…”
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2,2-Dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors by SONG SEOK SHIN, NOH, Min-Soo, YOUNG JOO BYUN, JIN KYU CHOI, JI YOUNG KIM, KYUNG MIN LIM, HA, Jun-Yong, JIN KWAN KIM, CHANG HOON LEE, CHUNG, Shin

“…A series of 2,2-dimethyl-5-[4-(methylsulfonyl)phenyl]-4-phenyl-3(2H)furanones was prepared and evaluated for their ability to inhibit cyclo-oxygenase-2 (COX-2)…”
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