Search Results - "HYUG MOO KWON"

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  1. 1

    TonEBP inhibits ciliogenesis by controlling aurora kinase A and regulating centriolar satellite integrity by Chinbold, Batchingis, Kwon, Hyug Moo, Park, Raekil

    Published in Cell communication and signaling (03-07-2024)
    “…Primary cilia on the surface of eukaryotic cells serve as sensory antennas for the reception and transmission in various cell signaling pathways. They are…”
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  2. 2

    Tonicity response element binding protein associated with neuronal cell death in the experimental diabetic retinopathy by Kim, Seong-Jae, Kim, Hwajin, Park, Jeongsook, Chung, Inyoung, Kwon, Hyug-Moo, Choi, Wan-Sung, Yoo, Ji-Myong

    Published in International journal of ophthalmology (18-12-2014)
    “…To study the contribution of tonicity response element binding protein (TonEBP) in retinal ganglion cell (RGC) death of diabetic retinopathy (DR). Diabetes was…”
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  3. 3

    Microglial TonEBP mediates LPS-induced inflammation and memory loss as transcriptional cofactor for NF-κB and AP-1 by Jeong, Gyu Won, Lee, Hwan Hee, Lee-Kwon, Whaseon, Kwon, Hyug Moo

    Published in Journal of neuroinflammation (08-12-2020)
    “…Abstract Background Microglia are brain-resident myeloid cells involved in the innate immune response and a variety of neurodegenerative diseases. In…”
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  4. 4

    Elevated Activity of Transcription Factor Nuclear Factor of Activated T-Cells 5 (NFAT5) and Diabetic Nephropathy by BINGMEI YANG, HODGKINSON, Andrea D, OATES, Peter J, HYUG MOO KWON, MILLWARD, Beverley A, DEMAINE, Andrew G

    Published in Diabetes (New York, N.Y.) (01-05-2006)
    “…Elevated Activity of Transcription Factor Nuclear Factor of Activated T-Cells 5 (NFAT5) and Diabetic Nephropathy Bingmei Yang 1 , Andrea D. Hodgkinson 1 ,…”
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  5. 5

    Intracellular cholesterol transport inhibition Impairs autophagy flux by decreasing autophagosome-lysosome fusion by Maharjan, Yunash, Dutta, Raghbendra Kumar, Son, Jinbae, Wei, Xiaofan, Park, Channy, Kwon, Hyug Moo, Park, Raekil

    Published in Cell communication and signaling (25-11-2022)
    “…Autophagy is an intracellular degradation process crucial for homeostasis. During autophagy, a double-membrane autophagosome fuses with lysosome through SNARE…”
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  6. 6

    Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury by Choi, Soo Youn, Lim, Sun Woo, Salimi, Shabnam, Yoo, Eun Jin, Lee-Kwon, Whaseon, Lee, Hwan Hee, Lee, Jun Ho, Mitchell, Braxton D, Sanada, Satoru, Parsa, Afshin, Kwon, Hyug Moo

    “…Diabetic nephropathy (DN) has become the single leading cause of ESRD in developed nations. Bearing in mind the paucity of effective treatment for DN and…”
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  7. 7

    TFEB activation triggers pexophagy for functional adaptation during oxidative stress under calcium deficient-conditions by Manandhar, Laxman, Dutta, Raghbendra Kumar, Devkota, Pradeep, Chhetri, Arun, Wei, Xiaofan, Park, Channy, Kwon, Hyug Moo, Park, Raekil

    Published in Cell communication and signaling (21-02-2024)
    “…Calcium is a ubiquitous intracellular messenger that regulates the expression of various genes involved in cell proliferation, differentiation, and motility…”
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  8. 8

    TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging by Lee, Hwan Hee, An, Seung Min, Ye, Byeong Jin, Lee, Jun Ho, Yoo, Eun Jin, Jeong, Gyu Won, Kang, Hyun Je, Alfadda, Assim A., Lim, Sun Woo, Park, Jiyoung, Lee-Kwon, Whaseon, Kim, Jae Bum, Choi, Soo Youn, Kwon, Hyug Moo

    Published in Nature communications (06-08-2019)
    “…Tonicity-responsive enhancer binding protein (TonEBP or NFAT5) is a regulator of cellular adaptation to hypertonicity, macrophage activation and T-cell…”
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  9. 9

    Catalase-deficient mice induce aging faster through lysosomal dysfunction by Dutta, Raghbendra Kumar, Lee, Joon No, Maharjan, Yunash, Park, Channy, Choe, Seong-Kyu, Ho, Ye-Shih, Kwon, Hyug Moo, Park, Raekil

    Published in Cell communication and signaling (06-12-2022)
    “…Lysosomes are a central hub for cellular metabolism and are involved in the regulation of cell homeostasis through the degradation or recycling of unwanted or…”
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  10. 10

    Roles of fluid shear stress and retinoic acid in the differentiation of primary cultured human podocytes by Yang, Seung Hee, Choi, Jin Woo, Huh, Dongeun, Jo, Hyung Ah, Kim, Sejoong, Lim, Chun Soo, Lee, Jung Chan, Kim, Hee Chan, Kwon, Hyug Moo, Jeong, Chang Wook, Kwak, Cheol, Joo, Kwon Wook, Kim, Yon Su, Kim, Dong Ki

    Published in Experimental cell research (01-05-2017)
    “…Due to the distinct features that distinguish immortalized podocyte cell lines from their in vivo counterparts, primary cultured human podocytes might be a…”
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  11. 11

    TAZ Suppresses NFAT5 Activity through Tyrosine Phosphorylation by Jang, Eun Jung, Jeong, Hana, Han, Ki Hwan, Kwon, Hyug Moo, Hong, Jeong-Ho, Hwang, Eun Sook

    Published in Molecular and Cellular Biology (01-12-2012)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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  12. 12

    A Gain-of-Function Cleavage of TonEBP by Coronavirus NSP5 to Suppress IFN-β Expression by Park, Hyun, Lee, Sang Min, Jeong, Su Ji, Kweon, Yeong Cheon, Shin, Go Woon, Kim, Whi Young, Lee-Kwon, Whaseon, Park, Chan Young, Kwon, Hyug Moo

    Published in Cells (Basel, Switzerland) (26-09-2024)
    “…Human coronaviruses (HCoVs) modify host proteins to evade the antiviral defense and sustain viral expansion. Here, we report tonicity-responsive enhancer…”
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  13. 13

    TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter by Yoo, Eun Jin, Lee, Hwan Hee, Ye, Byeong Jin, Lee, Jun Ho, Lee, Chae Young, Kang, Hyun Je, Jeong, Gyu Won, Park, Hyun, Lim, Sun Woo, Lee-Kwon, Whaseon, Kwon, Hyug Moo, Choi, Soo Youn

    Published in Frontiers in immunology (18-04-2019)
    “…TonEBP is a key transcriptional activator in macrophages with an M1 phenotype. High expression of TonEBP is associated with many inflammatory diseases. Heme…”
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  14. 14

    TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2 by Lee, Jun Ho, Lee, Hwan Hee, Ye, Byeong Jin, Lee-Kwon, Whaseon, Choi, Soo Youn, Kwon, Hyug Moo

    Published in Scientific reports (04-06-2015)
    “…TonEBP is a key transcription factor in cellular adaptation to hypertonic stress and also in macrophage activation. Since TonEBP is involved in inflammatory…”
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  15. 15

    Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance by Lee, Jun Ho, Suh, Jae Hee, Kang, Hyun Je, Choi, Soo Youn, Jung, Seok Won, Lee-Kwon, Whaseon, Park, Soo-Ah, Kim, Hajin, Ye, Byeong Jin, Yoo, Eun Jin, Jeong, Gyu Won, Park, Neung Hwa, Kwon, Hyug Moo

    Published in EBioMedicine (01-08-2020)
    “…High recurrence and chemoresistance drive the high mortality in hepatocellular carcinoma (HCC). Although cancer stem cells are considered to be the source of…”
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  16. 16

    Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes by Kim, Nam-Hoon, Hong, Bong-Ki, Choi, Soo Youn, Moo Kwon, Hyug, Cho, Chul-Soo, Yi, Eugene C, Kim, Wan-Uk

    Published in Experimental & molecular medicine (01-07-2013)
    “…The activation of nuclear factor of activated T cells 5 (NFAT5), a well-known osmoprotective factor, can be induced by isotonic stimuli, such as activated…”
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    TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy by Kang, Hyun Je, Yoo, Eun Jin, Lee, Hwan Hee, An, Seung Min, Park, Hyun, Lee-Kwon, Whaseon, Choi, Soo Youn, Kwon, Hyug Moo

    Published in Cells (Basel, Switzerland) (20-08-2020)
    “…The endoplasmic reticulum (ER) stress response and autophagy are important cellular responses that determine cell fate and whose dysregulation is implicated in…”
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  19. 19

    TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1 by Kang, Hyun Je, Park, Hyun, Yoo, Eun Jin, Lee, Jun Ho, Choi, Soo Youn, Lee-Kwon, Whaseon, Lee, Kyoo-young, Hur, Jin-Hoe, Seo, Jeong Kon, Ra, Jae Sun, Lee, Eun-A., Myung, Kyungjae, Kwon, Hyug Moo

    Published in iScience (27-09-2019)
    “…Polyubiquitination of proliferating cell nuclear antigen (PCNA) regulates the error-free template-switching mechanism for the bypass of DNA lesions during DNA…”
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  20. 20

    Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury by Yoo, Eun Jin, Lim, Sun Woo, Kang, Hyun Je, Park, Hyun, Yoon, Sora, Nam, Dougu, Sanada, Satoru, Kwon, Mi Jin, Lee-Kwon, Whaseon, Choi, Soo Youn, Kwon, Hyug Moo

    Published in Cells (Basel, Switzerland) (20-10-2019)
    “…TonEBP (tonicity-responsive enhancer binding protein) is a transcriptional regulator whose expression is elevated in response to various forms of stress…”
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