Search Results - "HYONGJONG, KOH"

Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH) by Yang, Jinsung, Kim, Min Ju, Yoon, Woongchang, Kim, Eun Young, Kim, Hyunjin, Lee, Yoonjeong, Min, Boram, Kang, Kyung Shin, Son, Jin H, Park, Hwan Tae, Chung, Jongkyeong, Koh, Hyongjong

“…DJ-1 is one of the causative genes for early onset familiar Parkinson's disease (PD) and is also considered to influence the pathogenesis of sporadic PD. DJ-1…”
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Pyruvate Dehydrogenase Kinase Protects Dopaminergic Neurons from Oxidative Stress in Drosophila DJ-1 Null Mutants by Lee, Yoonjeong, Kim, Jaehyeon, Kim, Hyunjin, Han, Ji Eun, Kim, Sohee, Kang, Kyong-Hwa, Kim, Donghoon, Kim, Jong-Min, Koh, Hyongjong

“…DJ-1 is one of the causative genes of early-onset familial Parkinson's disease (PD). As a result, DJ-1 influences the pathogenesis of sporadic PD. DJ-1 has…”
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PINK1 alleviates thermal hypersensitivity in a paclitaxel-induced Drosophila model of peripheral neuropathy by Kim, Young Yeon, Yoon, Jeong-Hyun, Um, Jee-Hyun, Jeong, Dae Jin, Shin, Dong Jin, Hong, Young Bin, Kim, Jong Kuk, Kim, Dong Hyun, Kim, Changsoo, Chung, Chang Geon, Lee, Sung Bae, Koh, Hyongjong, Yun, Jeanho, Chau, David

“…Paclitaxel is a representative anticancer drug that induces chemotherapy-induced peripheral neuropathy (CIPN), a common side effect that limits many anticancer…”
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Correction: PINK1 alleviates thermal hypersensitivity in a paclitaxel-induced Drosophila model of peripheral neuropathy by Kim, Young Yeon, Yoon, Jeong-Hyun, Um, Jee-Hyun, Jeong, Dae Jin, Shin, Dong Jin, Hong, Young Bin, Kim, Jong Kuk, Kim, Dong Hyun, Kim, Changsoo, Chung, Chang Geon, Lee, Sung Bae, Koh, Hyongjong, Yun, Jeanho

“…[This corrects the article DOI: 10.1371/journal.pone.0239126.]…”
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Silent Information Regulator 2 (Sir2) and Forkhead Box O (FOXO) Complement Mitochondrial Dysfunction and Dopaminergic Neuron Loss in Drosophila PTEN-induced Kinase 1 (PINK1) Null Mutant by Koh, Hyongjong, Kim, Hyunjin, Kim, Min Ju, Park, Jeehye, Lee, Hye-Jeong, Chung, Jongkyeong

“…PTEN-induced kinase 1 (PINK1), which is associated with early onset Parkinson disease, encodes a serine-threonine kinase that is critical for maintaining…”
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Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production by DOHOON, KIM, SUNHONG, KIM, HYONGJONG, KOH, SANG‐OH, YOON, AN‐SIK, CHUNGA, KYOUNG SANG, CHO, JONGKYEONG, CHUNG

“…The Akt/protein kinase B (PKB) serine/ threonine kinase is well known as an important mediator of many cell survival signaling pathways. Here, we demonstrate…”
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Nek6 overexpression antagonizes p53-induced senescence in human cancer cells by Jee, Hye Jin, Kim, Ae Jeong, Song, Naree, Kim, Hyun-Ju, Kim, Minjee, Koh, Hyongjong, Yun, Jeanho

“…Nek6 is an NIMA-related kinase that plays a critical role in mitotic cell cycle progression. Recent studies have shown that Nek6 is upregulated in various…”
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PINK1 and Parkin Ameliorate the Loss of Motor Activity and Mitochondrial Dysfunction Induced by Peripheral Neuropathy-Associated HSPB8 Mutants in Drosophila Models by Kang, Kyong-Hwa, Han, Ji Eun, Kim, Hyunjin, Kim, Sohee, Hong, Young Bin, Yun, Jeanho, Nam, Soo Hyun, Choi, Byung-Ok, Koh, Hyongjong

“…Charcot-Marie-Tooth disease (CMT) is a group of inherited peripheral nerve disorders characterized by progressive muscle weakness and atrophy, sensory loss,…”
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Drosophila Porin/VDAC affects mitochondrial morphology by Park, Jeehye, Kim, Yongsung, Choi, Sekyu, Koh, Hyongjong, Lee, Sang-Hee, Kim, Jin-Man, Chung, Jongkyeong

“…Voltage-dependent anion channel (VDAC) has been suggested to be a mediator of mitochondrial-dependent cell death induced by Ca(2+) overload, oxidative stress…”
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PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity by Koh, H.J., Dong-A University College of Medicine, Busan, Republic of Korea, Chung, J.K., Seoul National University, Seoul, Republic of Korea

“…Parkinson's disease (PD), the most prevalent neurodegenerative movement disorder, is characterized by an age-dependent selective loss of dopaminergic (DA)…”
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Cyclic AMP Inhibits Akt Activity by Blocking the Membrane Localization of PDK1 by Kim, S, Jee, K, Kim, D, Koh, H, Chung, J

“…Akt is a protein serine/threonine kinase that plays an important role in the mitogenic responses of cells to variable stimuli. Akt contains a pleckstrin…”
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PINK1 and Parkin to control mitochondria remodeling by Koh, Hyongjong, Chung, Jongkyeong

“…Parkinson's disease (PD), one of the most common neurodegenerative diseases, is characterized by movement disorders and a loss of dopaminergic (DA) neurons. PD…”
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Role of FOXO transcription factors in crosstalk between mitochondria and the nucleus by Kim, Sujin, Koh, Hyongjong

“…FOXO transcription factors are evolutionally conserved regulators of organismal life span downstream of insulin signaling. After integrating cellular signals…”
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Extracellular Zinc Activates p70 S6 Kinase through the Phosphatidylinositol 3-Kinase Signaling Pathway by Kim, S, Jung, Y, Kim, D, Koh, H, Chung, J

“…We have studied a possible role of extracellular zinc ion in the activation of p70S6k, which plays an important role in the progression of cells from the G 1…”
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PINK₁ and Parkin to control mitochondria remodeling by Hyongjong Koh, Jongkyeong Chung

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Drosophila Phosphoinositide-Dependent Kinase-1 Regulates Apoptosis and Growth via the Phosphoinositide 3-Kinase-Dependent Signaling Pathway by Cho, Kyoung Sang, Lee, Jun Hee, Kim, Sunhong, Kim, Dohoon, Koh, Hyongjong, Lee, Jihyun, Kim, Changsoo, Kim, Jaeseob, Chung, Jongkyeong

“…Phosphoinositide-dependent kinase-1 (PDK-1) is a central mediator of the cell signaling between phosphoinositide 3-kinase (PI3K) and various intracellular…”
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Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); A novel nuclear target of Akt by KOH, H, JEE, K, LEE, B, KIM, J, KIM, D, YUN, Y.-H, JUNG WOO KIM, CHOI, H.-S, CHUNG, J

“…Akt is stimulated by several growth factors, and mediates their cell survival signals. Recent studies have shown that Akt may play an intermediate role between…”
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MKP-3 Has Essential Roles as a Negative Regulator of the Ras/Mitogen-Activated Protein Kinase Pathway during Drosophila Development by Kim, Myungjin, Cha, Guang-Ho, Kim, Sunhong, Lee, Jun Hee, Park, Jeehye, Koh, Hyongjong, Choi, Kang-Yell, Chung, Jongkyeong

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inhibition of Akt and Its Anti-apoptotic Activities by Tumor Necrosis Factor-induced Protein Kinase C-related Kinase 2 (PRK2) Cleavage by Koh, Hyongjong, Lee, Kyoung Hoa, Kim, Dohoon, Kim, Sunhong, Kim, Jung Woo, Chung, Jongkyeong

“…Akt is stimulated by several growth factors and has a major anti-apoptotic role in the cell. Therefore, we hypothesized that a pathway leading to the…”
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Assessment of mitophagy in mt‐Keima Drosophila revealed an essential role of the PINK1‐Parkin pathway in mitophagy induction in vivo by Kim, Young Yeon, Um, Jee‐Hyun, Yoon, Jeong‐Hyun, Kim, Hyunjin, Lee, Da‐Ye, Lee, Yoon Jung, Jee, Hye Jin, Kim, Young Mi, Jang, Jae Sung, Jang, Yoon‐Gu, Chung, Jongkyeong, Park, Hwan Tae, Finkel, Toren, Koh, Hyongjong, Yun, Jeanho

“…ABSTRACTMitophagy has been implicated in mitochondrial quality control and in various human diseases. However, the study of in vivo mitophagy remains limited…”
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