Search Results - "HYNES, R.O."

440 Screening of Surface Markers Revealed That CD24 is Overexpressed in Malignant Pleural Effusions and is Required for Xenograft Tumor Formation by Yao, X, Labelle, M, Lamb, C.R, Dugan, J.M, Williamson, C.A, Hynes, R.O, Kittrup, K.D

Get full text

Fibrinogen and von Willebrand factor‐independent platelet aggregation in vitro and in vivo by YANG, H., REHEMAN, A., CHEN, P., ZHU, G., HYNES, R.O., FREEDMAN, J., WAGNER, D.D., NI, H.

Get full text

Integrins in vascular development by Hynes, R O, Bader, B L, Hodivala-Dilke, K

“…Many growth factors and their protein kinase receptors play a role in regulating vascular development. In addition, cell adhesion molecules, such as integrins…”
Get full text

Cell–matrix adhesion in vascular development by HYNES, R. O.

“…Vascular development requires correct interactions among endothelial cells, pericytes and surrounding cells. These interactions involve many cell adhesion…”
Get full text

CELL-MATRIX ADHESION IN VASCULAR DEVELOPMENT by Hynes, R.O.

Get full text

Galectin-4 driven immunosuppression in pancreatic ductal adenocarcinoma by Lidström, T., Cumming, J., Gaur, R., Tian, C., Franklin, O., Hynes, R.O., Tuveson, D.A., Öhlund, D.

Get full text

Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin by GEORGE, E. L, GEORGES-LABOUESSE, E. N, PATEL-KING, R. S, RAYBURN, H, HYNES, R. O

“…To examine the role of fibronectin in vivo, we have generated mice in which the fibronectin gene is inactivated. Heterozygotes have one half normal levels of…”
Get full text

Toward a genetic analysis of cell-matrix adhesion by Hynes, R O, George, E L, Georges, E N, Guan, J L, Rayburn, H, Yang, J T

Get more information

The diverse roles of integrins and their ligands in angiogenesis by Hynes, R O, Lively, J C, McCarty, J H, Taverna, D, Francis, S E, Hodivala-Dilke, K, Xiao, Q

Get full text

β3 Integrins Regulate Lymphocyte Migration and Cytokine Responses in Heart Transplant Rejection by Lacy‐Hulbert, A., Ueno, T., Ito, T., Jurewicz, M., Izawa, A., Smith, R. N., Chase, C. M., Tanaka, K., Fiorina, P., Russell, P. S., Auchincloss, H., Sayegh, M. H., Hynes, R. O., Abdi, R.

“…Integrin αvβ3 is important for cell survival, signaling and migration, particularly during angiogenesis and tumorigenesis, where it has been proposed as a…”
Get full text

Guidelines for human embryonic stem cell research by Moreno, Jonathan D, Hynes, Richard O

Get full text

A novel, tissue-specific integrin subunit, beta nu, expressed in the midgut of Drosophila melanogaster by Yee, G H, Hynes, R O

“…The integrins are a family of cell surface receptors for extracellular matrix proteins and counter-receptors on other cells. We have used the polymerase chain…”
Get full text

Drosophila syndecan: conservation of a cell-surface heparan sulfate proteoglycan by Spring, J, Paine-Saunders, S.E, Hynes, R.O, Bernfield, M

“…In mammals, cell-surface heparan sulfate is required for the action of basic fibroblast growth factor, fibronectin, antithrombin III, as well as other…”
Get full text

Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo by Ffrench-Constant, C, Hynes, R O

“…The primary gene transcript for the adhesive extracellular matrix glycoprotein fibronectin (FN) is alternatively spliced in three regions (EIIIA, EIIIB and V)…”
Get full text

Drosophila PS1 integrin is a laminin receptor and differs in ligand specificity from PS2 by Gotwals, P.J. (Massachusetts Institute of Technology, Cambridge, MA.), Fessler, L.I, Wehrli, M, Hynes, R.O

“…We have expressed Drosophila position-specific (PS) integrins on the surfaces of Schneider S2 cells and tested for adhesion and spreading on various matrix…”
Get full text

Tumour suppressor genes and angiogenesis: the role of TP53 in fibroblasts by Stellmach, V., Volpert, O.V., Crawford, S.E., Lawler, J., Hynes, R.O., Bouck, N.

Get full text

Analyses of PS integrin functions during Drosophila development by ZUSMAN, S, GRINBLAT, Y, YEE, G, KAFATOS, F. C, HYNES, R. O

“…The Drosophila position-specific (PS) antigens are homologues of the vertebrate integrins, a family of transmembrane proteins that function in cell-matrix and…”
Get full text

Patterns of fibronectin gene expression and splicing during cell migration in chicken embryos by Ffrench-Constant, C, Hynes, R O

“…A variety of evidence suggests that fibronectin (FN) promotes cell migration during embryogenesis, and it has been suggested that the deposition of FN along…”
Get full text

Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos by Goh, K L, Yang, J T, Hynes, R O

“…Alpha5beta1 integrin is a cell surface receptor that mediates cell-extracellular matrix adhesions by interacting with fibronectin. Alpha5 subunit-deficient…”
Get full text

Requirements for integrins during Drosophila development by Zusman, S, Patel-King, R S, Ffrench-Constant, C, Hynes, R O

“…The common beta subunit of the PS antigens of Drosophila is homologous with vertebrate integrins and is encoded by the lethal(1)myospheroid gene. We have…”
Get full text