Search Results - "HYGINO, Joana"
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Elevated proportion of TLR2- and TLR4-expressing Th17-like cells and activated memory B cells was associated with clinical activity of cerebral cavernous malformations
Published in Journal of neuroinflammation (02-02-2022)“…Recent evidences have suggested the involvement of toll-like receptor (TLR)-4 in the pathogenesis of cerebral cavernous malformations (CCM). Elevated frequency…”
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2
Fatigue favors in vitro Th1 and Th17-like cell expansion and reduces corticoid sensitivity in MS patients
Published in Journal of neuroimmunology (15-02-2017)“…Abstract Fatigue is a common “ ghost ” symptom in patients with multiple sclerosis (MS), an autoimmune disease mediated by T cells that target myelin antigens…”
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3
Low sensitivity to glucocorticoid inhibition of in vitro Th17-related cytokine production in multiple sclerosis patients is related to elevated plasma lipopolysaccharide levels
Published in Clinical immunology (Orlando, Fla.) (01-08-2013)“…Abstract Exogenous glucocorticoid plays an important role in controlling clinical relapses of multiple sclerosis (MS), but the response to this treatment…”
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4
B- and T-cell subpopulations in patients with severe idiopathic membranous nephropathy may predict an early response to rituximab
Published in Kidney international (01-07-2017)“…Primary membranous nephropathy (PMN) is characterized by antibodies to the podocyte, but little is known about B- and T-cell populations and their response to…”
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Serotonin decreases the production of Th1/Th17 cytokines and elevates the frequency of regulatory CD4+ T‐cell subsets in multiple sclerosis patients
Published in European journal of immunology (01-08-2018)“…Excessive levels of proinflammatory cytokines in the CNS are associated with reduced serotonin (5‐HT) synthesis, a neurotransmitter with diverse immune…”
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Combined exercise training reduces fatigue and modulates the cytokine profile of T-cells from multiple sclerosis patients in response to neuromediators
Published in Journal of neuroimmunology (15-04-2016)“…Abstract Fatigue is a common and disabling symptom of multiple sclerosis (MS), a classical Th1 and Th17-mediated autoimmune disease. There is no effective…”
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Selective serotonin reuptake inhibitor attenuates the hyperresponsiveness of TLR2+ and TLR4+ Th17/Tc17‐like cells in multiple sclerosis patients with major depression
Published in Immunology (01-03-2021)“…Summary Elevated frequency of Th17‐like cells expressing Toll‐like receptors (TLRs) has been recently associated with relapsing–remitting multiple sclerosis…”
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Vitamin D modulates different IL-17-secreting T cell subsets in multiple sclerosis patients
Published in Journal of neuroimmunology (15-10-2016)“…Abstract Vitamin D deficiency is an environmental risk factor for MS, a Th17 cell-mediated autoimmune disease that results in demyelination in the CNS…”
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9
Different interleukin‐17‐secreting Toll‐like receptor+ T‐cell subsets are associated with disease activity in multiple sclerosis
Published in Immunology (01-06-2018)“…Summary Signalling through Toll‐like receptors (TLRs) may play a role in the pathogenesis of autoimmune diseases, such as multiple sclerosis (MS). In the…”
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Interleukin‐17‐ and interleukin‐22‐secreting myelin‐specific CD4+ T cells resistant to corticoids are related with active brain lesions in multiple sclerosis patients
Published in Immunology (01-02-2016)“…Summary Multiple sclerosis (MS) is thought to be an autoimmune disorder. It is believed that immunological events in the early stages have great impact on the…”
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Hyperresponsiveness of Corticoid-Resistant Th17/Tc-17 Cells to TLR-2 and TLR-4 Ligands is a Feature of Multiple Sclerosis Patients at Higher Risk of Therapy Failure
Published in Journal of inflammation research (01-11-2024)“…The presence of T cells expressing TLR-2 and TLR-4 has been associated with relapsing-remitting multiple sclerosis (RRMS) pathogenesis. Here, we evaluated…”
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12
Modeling the Heart Rate Response to Step Test
Published in Medicine and science in sports and exercise (01-05-2004)Get full text
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Modeling the Heart Rate Response to Step Test
Published in Medicine and science in sports and exercise (01-05-2004)Get full text
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14
Pregnancy favors circulating IL-21-secreting T FH -like cell recovery in ARV-treated HIV-1-infected women
Published in American journal of reproductive immunology (1989) (01-02-2020)“…Pregnancy appears to favor maternal antibody production. In contrast, by damaging follicular helper T cells (T ), HIV-1 infection compromises protective…”
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Pregnancy favors the expansion of circulating functional follicular helper T Cells
Published in Journal of reproductive immunology (01-06-2017)“…Highlights • The pregnancy favors the expansion of CXCR3+ PD-1+ ICOS+ TFH cells. • The proportion of IL-21+ TFH cells was higher in pregnant women. • Serum…”
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The Ex Vivo Production of IL-6 and IL-21 by CD4+ T Cells is Directly Associated with Neurological Disability in Neuromyelitis Optica Patients
Published in Journal of clinical immunology (2013)“…Neuromyelitis optica (NMO), also known as Devic’s disease, is an autoimmune, inflammatory disorder of the central nervous system (CNS) in which the immune…”
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Pregnancy favors circulating IL‐21–secreting TFH‐like cell recovery in ARV‐treated HIV‐1–infected women
Published in American journal of reproductive immunology (1989) (01-02-2020)“…Problem Pregnancy appears to favor maternal antibody production. In contrast, by damaging follicular helper T cells (TFH), HIV‐1 infection compromises…”
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Enhanced Th17 phenotype in individuals with generalized anxiety disorder
Published in Journal of neuroimmunology (15-12-2010)“…Abstract The generalized anxiety disorder (GAD) is often a debilitating chronic condition, characterized by long-lasting anxiety that is not focused on any…”
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Dopamine favors expansion of glucocorticoid-resistant IL-17-producing T cells in multiple sclerosis
Published in Brain, behavior, and immunity (01-10-2014)“…Abstract Dopamine (DA) is a neurotransmitter produced mainly in the central nervous system (CNS) that has immunomodulatory actions on T cells. As the multiple…”
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Endogenous interleukin‐6 amplifies interleukin‐17 production and corticoid‐resistance in peripheral T cells from patients with multiple sclerosis
Published in Immunology (01-12-2014)“…Summary Interleukin‐6 (IL‐6) has been implicated in the induction of pathogenic IL‐17‐producing T cells in autoimmune diseases, and studies evaluating the role…”
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