Search Results - "HUSON, Les"

Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial by Prague, Julia K, MBBS, Roberts, Rachel E, MBBS, Comninos, Alexander N, PhD, Clarke, Sophie, MBBS, Jayasena, Channa N, PhD, Nash, Zachary, MBBS, Doyle, Chedie, BSN, Papadopoulou, Deborah A, BSc, Bloom, Stephen R, Prof, Mohideen, Pharis, MD, Panay, Nicholas, MRCOG, Hunter, Myra S, Prof, Veldhuis, Johannes D, Prof, Webber, Lorraine C, MBBS, Huson, Les, PhD, Dhillo, Waljit S, Prof

“…Summary Background Hot flushes affect 70% of menopausal women and often severely impact physical, psychosocial, sexual, and overall wellbeing. Hormone…”
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TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis by Owen, David R, Fan, Jinjiang, Campioli, Enrico, Venugopal, Sathvika, Midzak, Andrew, Daly, Edward, Harlay, Aline, Issop, Leeyah, Libri, Vincenzo, Kalogiannopoulou, Dimitra, Oliver, Eduardo, Gallego-Colon, Enrique, Colasanti, Alessandro, Huson, Les, Rabiner, Eugenii A, Suppiah, Puvan, Essagian, Charles, Matthews, Paul M, Papadopoulos, Vassilios

“…The 18 kDa translocator protein (TSPO) is a ubiquitous conserved outer mitochondrial membrane protein implicated in numerous cell and tissue functions,…”
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Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study by Libri, Vincenzo, MD, Yandim, Cihangir, PhD, Athanasopoulos, Stavros, MD, Loyse, Naomi, PhD, Natisvili, Theona, MSc, Law, Pui Pik, MSc, Chan, Ping Kei, PhD, Mohammad, Tariq, MBBS, Mauri, Marta, MSc, Tam, Kin Tung, BSc, Leiper, James, PhD, Piper, Sophie, MSc, Ramesh, Aravind, BM BCh, Parkinson, Michael H, MBBS, Huson, Les, PhD, Giunti, Paola, MD, Festenstein, Richard, Prof

“…Summary Background Friedreich's ataxia is a progressive degenerative disorder caused by deficiency of the frataxin protein. Expanded GAA repeats within intron…”
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A second dose of kisspeptin-54 improves oocyte maturation in women at high risk of ovarian hyperstimulation syndrome: a Phase 2 randomized controlled trial by Abbara, Ali, Clarke, Sophie, Islam, Rumana, Prague, Julia K., Comninos, Alexander N., Narayanaswamy, Shakunthala, Papadopoulou, Deborah, Roberts, Rachel, Izzi-Engbeaya, Chioma, Ratnasabapathy, Risheka, Nesbitt, Alexander, Vimalesvaran, Sunitha, Salim, Rehan, Lavery, Stuart A., Bloom, Stephen R., Huson, Les, Trew, Geoffrey H., Dhillo, Waljit S.

“…Abstract STUDY QUESTION Can increasing the duration of LH-exposure with a second dose of kisspeptin-54 improve oocyte maturation in women at high risk of…”
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Use of the Selective Oral Neuraminidase Inhibitor Oseltamivir to Prevent Influenza by Hayden, Frederick G, Atmar, Robert L, Schilling, Margo, Johnson, Casey, Poretz, Donald, Paar, David, Huson, Les, Ward, Penelope, Mills, Roger G

“…Yearly immunization with inactivated vaccines is the main strategy for the prevention of influenza. 1 When substantial antigenic drift occurs after the…”
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Acoustic compliance with permit conditions—What does it mean? by Cooper, Steven E., huson, les

“…The use of a dBA L90/L95 limit for operational wind farms, that rely upon a regression analysis of wind and noise that is averaged over time, does not relate…”
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Quality of Life and Physical Function in Older Patients on Dialysis: A Comparison of Assisted Peritoneal Dialysis with Hemodialysis by Iyasere, Osasuyi U, Brown, Edwina A, Johansson, Lina, Huson, Les, Smee, Joanna, Maxwell, Alexander P, Farrington, Ken, Davenport, Andrew

“…In-center hemodialysis (HD) is often the default dialysis modality for older patients. Few centers use assisted peritoneal dialysis (PD), which enables…”
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Reduced MicroRNA-150 Is Associated with Poor Survival in Pulmonary Arterial Hypertension by RHODES, Christopher J, WHARTON, John, CONDLIFFE, Robin, ELLIOT, Charles A, KIELY, David G, HUSON, Les, GHOFRANI, Hossein A, TIEDE, Henning, SCHERMULY, Ralph, ZEIHER, Andreas M, DIMMELER, Stefanie, WILKINS, Martin R, BOON, Reinier A, ROEXE, Tino, TSANG, Hilda, WOJCIAK-STOTHARD, Beata, CHAKRABARTI, Anob, HOWARD, Luke S, GIBBS, J. Simon R, LAWRIE, Allan

“…MicroRNAs (miRNAs or miRs) are implicated in the pathogenesis of various cardiovascular diseases, including pulmonary arterial hypertension (PAH). We sought to…”
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Risk of Ovarian Cancer Relapse score: a prognostic algorithm to predict relapse following treatment for advanced ovarian cancer by Rizzuto, Ivana, Stavraka, Chara, Chatterjee, Jayanta, Borley, Jane, Hopkins, Thomas Glass, Gabra, Hani, Ghaem-Maghami, Sadaf, Huson, Les, Blagden, Sarah P

“…The aim of this study was to construct a prognostic index that predicts risk of relapse in women who have completed first-line treatment for ovarian cancer…”
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Sustained cardiovascular actions of APJ agonism during renin-angiotensin system activation and in patients with heart failure by Barnes, Gareth D, Alam, Shirjel, Carter, Gordon, Pedersen, Christian M, Lee, Kristina M, Hubbard, Thomas J, Veitch, Scott, Jeong, Herim, White, Audrey, Cruden, Nicholas L, Huson, Les, Japp, Alan G, Newby, David E

“…To assess cardiovascular actions of APJ agonism during prolonged (Pyr(1))apelin-13 infusion and renin-angiotensin system activation. Forty-eight volunteers and…”
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Efficacy of Enfuvirtide in Patients Infected with Drug-Resistant HIV-1 in Europe and Australia by Lazzarin, Adriano, Clotet, Bonaventura, Cooper, David, Reynes, Jacques, Arastéh, Keikawus, Nelson, Mark, Katlama, Christine, Stellbrink, Hans-Jürgen, Delfraissy, Jean-François, Lange, Joep, Huson, Les, DeMasi, Ralph, Wat, Cynthia, Delehanty, John, Drobnes, Claude, Salgo, Miklos

“…This randomized study, conducted in Europe and Australia, included 335 patients in the enfuvirtide group and 169 in a control group treated with only an…”
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Supplementation with Iron in Pulmonary Arterial Hypertension. Two Randomized Crossover Trials by Howard, Luke S G E, He, Jianguo, Watson, Geoffrey M J, Huang, Li, Wharton, John, Luo, Qin, Kiely, David G, Condliffe, Robin, Pepke-Zaba, Joanna, Morrell, Nicholas W, Sheares, Karen K, Ulrich, Anna, Quan, Ruilin, Zhao, Zhihui, Jing, Xiaoli, An, Chenhong, Liu, Zhihong, Xiong, Changming, Robbins, Peter A, Dawes, Timothy, de Marvao, Antonio, Rhodes, Christopher J, Richter, Manuel J, Gall, Henning, Ghofrani, Hossein A, Zhao, Lan, Huson, Les, Wilkins, Martin R

“…Iron deficiency, in the absence of anemia, is common in patients with idiopathic and heritable pulmonary arterial hypertension (PAH) and is associated with a…”
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Reply: Clinical trial registry alone is not adequate: on the perception of possible endpoint switching and P-hacking by Abbara, Ali, Clarke, Sophie, Islam, Rumana, Prague, Julia K, Comninos, Alexander, Narayanaswamy, Shakunthala, Papadopoulou, Deborah A, Roberts, Rachel E, Izzi-Engbeaya, Chioma N, Ratnasabapathy, Risheka, Nesbitt, Alexander, Vimalesvaran, Sunitha, Salim, Rehan, Lavery, Stuart A, Bloom, Stephen R, Huson, Les, Trew, Geoffrey H, Dhillo, Waljit S

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Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: A phase 2, randomised, double-blind, placebo controlled trial by Prague, Julia, Roberts, Rachel, Comninos, Alexander, Clarke, Sophie, Jayasena, Channa, Nash, Zachary, Doyle, Chedie, Papadopoulou, Deborah, Bloom, Stephen, Mohideen, Pharis, Panay, Nicholas, Hunter, Myra, Veldhuis, Johannes, Webber, Lorraine, Huson, Les, Dhillo, Waljit

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Effectiveness of Oseltamivir in Preventing Influenza in Household Contacts: A Randomized Controlled Trial by Welliver, Robert, Monto, Arnold S, Carewicz, Otmar, Schatteman, Edwig, Hassman, Michael, Hedrick, James, Jackson, Helen C, Huson, Les, Ward, Penelope, Oxford, John S, for the Oseltamivir Post Exposure Prophylaxis Investigator Group

“…CONTEXT Influenza virus is easily spread among the household contacts of an infected person, and prevention of influenza in household contacts can control…”
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Book reviews by Huson, Les

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Book reviews by Huson, Les

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Book Reviews by Huson, Les

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Modelling Survival Data in Medical Research by Huson, Les

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Clinical Trials by Huson, Les

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