Search Results - "HUREL, S. J"

Adiponectin and its gene variants as risk factors for insulin resistance, the metabolic syndrome and cardiovascular disease by Gable, D.R., Hurel, S.J., Humphries, S.E.

“…The increasing prevalence of obesity and metabolic syndrome/insulin resistance has attracted considerable interest due to their identification as risk factors…”
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Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus by Wootton, P.T.E, Stephens, J.W., Hurel, S.J., Durand, H., Cooper, J., Ninio, E., Humphries, S.E., Talmud, P.J.

“…Lipoprotein associated phospholipase A2 (Lp-PLA2) modulates low-density lipoprotein (LDL) oxidation by hydrolysing oxidised phospholipids present on particle…”
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Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease by VAIDYA, B, IMRIE, H, KEMP, E. H, YOUNG, E. T, WEETMAN, A. P, KENDALL-TAYLOR, P, PEARCE, S. H. S, GEATCH, D. R, PERROS, P, BALL, S. G, BAYLIS, P. H, CARR, D, HUREL, S. J, JAMES, R. A, KELLY, W. F

“…Although autoimmune Addison's disease (AAD) may occur as a component of the monogenic autoimmune polyendocrinopathy type 1 syndrome (APS1), it is most commonly…”
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A randomised controlled trial to compare minimally invasive glucose monitoring devices with conventional monitoring in the management of insulin-treated diabetes mellitus (MITRE) by Newman, S P, Cooke, D, Casbard, A, Walker, S, Meredith, S, Nunn, A, Steed, L, Manca, A, Sculpher, M, Barnard, M, Kerr, D, Weaver, J, Ahlquist, J, Hurel, S J

“…To evaluate whether the additional information provided by minimally invasive glucose monitors results in improved glycaemic control in people with poorly…”
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The short Synacthen and insulin stress tests in the assessment of the hypothalamic-pituitary-adrenal axis by Hurel, S J, Thompson, C J, Watson, M J, Harris, M M, Baylis, P H, Kendall-Taylor, P

“…The best dynamic test for the assessment of the hypothalamic-pituitary-adrenal axis and the interpretation of the cortisol levels, remain a matter of…”
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Association between the rs1050450 glutathione peroxidase-1 (C > T) gene variant and peripheral neuropathy in two independent samples of subjects with diabetes mellitus by Tang, T.S, Prior, S.L, Li, K.W, Ireland, H.A, Bain, S.C, Hurel, S.J, Cooper, J.A, Humphries, S.E, Stephens, J.W

“…Abstract Glutathione peroxidase-1 (GPx-1) is an endogenous anti-oxidant enzyme. The T allele of the GPx-1 rs1050450 (C > T) gene variant is associated with…”
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Relationship of physical exercise and ageing to growth hormone production by Hurel, S. J., Koppiker, N., Newkirk, J., Close, P. R., Miller, M., Mardell, R., Wood, P. J., Kendall-Taylor, P.

“…OBJECTIVE The normal decline in physiological function with ageing is associated with a decrease in bioavailable growth hormone. Growth hormone has been shown…”
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Association between the rs4880 superoxide dismutase 2 (C>T) gene variant and coronary heart disease in diabetes mellitus by Jones, D.A, Prior, S.L, Tang, T.S, Bain, S.C, Hurel, S.J, Humphries, S.E, Stephens, J.W

“…Abstract Mitochondrial superoxide dismutase 2 (SOD2) is an endogenous anti-oxidant enzyme. The rs4880 gene variant results in a C>T substitution, influencing…”
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Randomized controlled trial to assess the impact of continuous glucose monitoring on HbA1c in insulin-treated diabetes (MITRE Study) by Cooke, D., Hurel, S. J., Casbard, A., Steed, L., Walker, S., Meredith, S., Nunn, A. J., Manca, A., Sculpher, M., Barnard, M., Kerr, D., Weaver, J. U., Ahlquist, J., Newman, S. P.

“…Aims  To determine whether continuous glucose information provided through use of either the GlucoWatch G2 Biographer or the MiniMed continuous glucose…”
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Biochemical marker for cerebral oedema complicating severe diabetic ketoacidosis by Chan, N. N., Hurel, S. J.

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Insulin Reduces Serum Glycosylphosphatidylinositol Phospholipase D Levels in Human Type I Diabetic Patients and Streptozotocin Diabetic Rats by Schofield, J.N., Stephens, J.W., Hurel, S.J., Bell, K.M., deSouza, J.B., Rademacher, T.W.

“…The enzyme glycosylphosphatidylinositol phospholipase D has a postulated role in the insulin-mimetic signaling pathway of glycosylphosphatidylinositol…”
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Brain natriuretic peptide as a potential marker of diastolic dysfunction in type 2 diabetes by Chan, N N, Hurel, S J

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A long-range PCR method for genotyping promoter variants in the interleukin-6 gene by Stephens, J W, Palmen, J M, Hurel, S J, Humphries, S E

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Hyperhomocysteinemia and macroangiopathy in type 2 diabetes by Chan, N N, Tan, T M, Hurel, S J

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Hyperpnoea and emesis in a diabetic man by Monjardino, J, Smith, D, Tisdall, M, Chan, N N, Hurel, S J

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Avascular necrosis secondary to postoperative steroid therapy by J. HUREL & P. KENDALL-TAYLOR, S.

“…Abstract Hypothalamic and pituitary tumours may present with vague symptoms owing to excess or lack of hormone production, including diabetes insipidus…”
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Clinical decision making: managing postprandial hyperglycemia by Hurel, S J, Mohan, V

“…The primary objective of treating all patients with diabetes is to establish and maintain near-normal blood glucose levels to prevent microvascular and…”
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Development and piloting of an acceptability questionnaire for continuous glucose monitoring devices by Steed, L, Cooke, D, Hurel, S J, Newman, S P

“…User acceptability of new health technologies is important in determining their widespread use and adoption. The aim of this current study was twofold: first,…”
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The Significant Increase in Cardiovascular Disease Risk in APOE epsilon 4 Carriers is Evident Only in Men Who Smoke: Potential Relationship Between Reduced Antioxidant Status and ApoE4 by Talmud, P J, Stephens, J W, Hawe, E, Demissie, S, Cupples, LA, Hurel, S J, Humphries, SE, Ordovas, J M

“…Data from 1668 men (316 cardiovascular disease events) from the Framingham Offspring Study was reanalysed, specifically examining APOE:smoking interactions…”
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The effect of acute (60 minute) insulin stimulation upon human skeletal muscle glycogen synthase and protein phosphatase-1 in non-insulin-dependent diabetic patients and control subjects by Barriocanal, L A, Borthwick, A C, Stewart, M, Wells, A, Hurel, S J, Yeaman, S J, Taylor, R

“…Previous studies have established that activation of muscle glycogen synthase (GS) is abnormal in non-insulin-dependent diabetes mellitus (NIDDM)…”
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