Search Results - "HUNTLEY, Brenda K"

CRRL269: a novel designer and renal-enhancing pGC-A peptide activator by Chen, Yang, Harty, Gail J, Huntley, Brenda K, Iyer, Seethalakshmi R, Heublein, Denise M, Harders, Gerald E, Meems, Laura, Pan, Shuchong, Sangaralingham, S Jeson, Ichiki, Tomoko, Burnett, Jr, John C

“…The natriuretic peptides (NPs) B-type NP (BNP) and urodilatin (URO) exert renal protective properties via the particulate guanylyl cyclase A receptor (pGC-A)…”
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Design, Synthesis, and Actions of a Novel Chimeric Natriuretic Peptide: CD-NP by Lisy, Ondrej, MD, PhD, Huntley, Brenda K, McCormick, Daniel J., PhD, Kurlansky, Paul A., MD, Burnett, John C., MD

“…Design, Synthesis, and Actions of a Novel Chimeric Natriuretic Peptide: CD-NP Ondrej Lisy, Brenda K. Huntley, Daniel J. McCormick, Paul A. Kurlansky, John C…”
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Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: Regulation and therapeutic implications by Ichiki, Tomoko, Schirger, John A, Huntley, Brenda K, Brozovich, Frank V, Maleszewski, Joseph J, Sandberg, Sharon M, Sangaralingham, S. Jeson, Park, Soon J, Burnett, John C

“…Abstract Left ventricular assist device (LVAD) support has been used in the treatment of end-stage heart failure (HF), however use of anti-fibrotic…”
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Pro-B-type natriuretic peptide-1-108 processing and degradation in human heart failure by Huntley, Brenda K, Sandberg, Sharon M, Heublein, Denise M, Sangaralingham, S Jeson, Burnett, Jr, John C, Ichiki, Tomoko

“…We have reported that pro-B-type natriuretic peptide (BNP)-1-108 circulates and is processed to mature BNP1-32 in human blood. Building on these findings, we…”
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Differential expression of the pro-natriuretic peptide convertases corin and furin in experimental heart failure and atrial fibrosis by Ichiki, Tomoko, Boerrigter, Guido, Huntley, Brenda K, Sangaralingham, S Jeson, McKie, Paul M, Harty, Gail J, Harders, Gerald E, Burnett, Jr, John C

“…In heart failure (HF), the cardiac hormone natriuretic peptides (NPs) atrial (ANP), B-type (BNP), and C-type (CNP) play a key role to protect cardiac…”
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Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: a kidney-heart connection by Martin, Fernando L, McKie, Paul M, Cataliotti, Alessandro, Sangaralingham, S Jeson, Korinek, Josef, Huntley, Brenda K, Oehler, Elise A, Harders, Gerald E, Ichiki, Tomoko, Mangiafico, Sarah, Nath, Karl A, Redfield, Margaret M, Chen, Horng H, Burnett, Jr, John C

“…Impaired renal function with loss of nephron number in chronic renal disease (CKD) is associated with increased cardiovascular morbidity and mortality…”
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CD-NP: a novel engineered dual guanylyl cyclase activator with anti-fibrotic actions in the heart by Martin, Fernando L, Sangaralingham, S Jeson, Huntley, Brenda K, McKie, Paul M, Ichiki, Tomoko, Chen, Horng H, Korinek, Josef, Harders, Gerald E, Burnett, Jr, John C

“…Natriuretic peptides (NPs) are cardioprotective through the activation of guanylyl cyclase (GC) receptors A and B. CD-NP, also known as cenderitide, is a novel…”
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Secretion of Glycosylated Pro―B-Type Natriuretic Peptide from Normal Cardiomyocytes by TONNE, Jason M, CAMPBELL, Jarryd M, CATALIOTTI, Alessandro, OHMINE, Seiga, THATAVA, Tayaramma, SAKUMA, Toshie, MACHERET, Fima, HUNTLEY, Brenda K, BURNETT, John C, IKEDA, Yasuhiro

“…B-type natriuretic peptide (BNP), a key cardiac hormone in cardiorenal homeostasis, is produced as a 108 amino acid prohormone, proBNP1-108, which is converted…”
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Immunoreactivity and Guanosine 3′,5′-Cyclic Monophosphate Activating Actions of Various Molecular Forms of Human B-Type Natriuretic Peptide by Heublein, Denise M, Huntley, Brenda K, Boerrigter, Guido, Cataliotti, Alessandro, Sandberg, Sharon M, Redfield, Margaret M, Burnett, John C

“…Recent studies support the speculation that different molecular forms of the cardiac hormone BNP with differential biological activity may circulate in heart…”
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BNP Molecular Forms and Processing by the Cardiac Serine Protease Corin by Ichiki, Tomoko, Huntley, Brenda K., Burnett, John C.

“…The cardiac hormone, B-type natriuretic peptide (BNP), is one of human natriuretic peptides which possesses cardiorenal protective actions and is used as a…”
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Brain Natriuretic Peptide Is Produced in Cardiac Fibroblasts and Induces Matrix Metalloproteinases by Tsuruda, Toshihiro, Boerrigter, Guido, Huntley, Brenda K, Noser, Josh A, Cataliotti, Alessandro, Costello-Boerrigter, Lisa C, Chen, Horng H, Burnett, John C

“…ABSTRACT—Cardiac fibroblasts (CFs) produce extracellular matrix proteins and participate in the remodeling of the heart. It is unknown if brain natriuretic…”
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A Human Atrial Natriuretic Peptide Gene Mutation Reveals a Novel Peptide With Enhanced Blood Pressure-Lowering, Renal-Enhancing, and Aldosterone-Suppressing Actions by McKie, Paul M., MD, Cataliotti, Alessandro, MD, PhD, Huntley, Brenda K., BS, Martin, Fernando L., MD, Olson, Timothy M., MD, Burnett, John C., MD

“…Objectives We sought to determine the physiologic actions and potential therapeutic applications of mutant atrial natriuretic peptide (mANP). Background The…”
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B-type natriuretic peptide and extracellular matrix protein interactions in human cardiac fibroblasts by Huntley, Brenda K., Ichiki, Tomoko, Sangaralingham, S. Jeson, Chen, Horng H., Burnett Jr, John C.

“…Cardiac fibroblasts (CFs) regulate myocardial remodeling by proliferating, differentiating, and secreting extracellular matrix (ECM) proteins. B‐type…”
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Losses of Chromosomal Arms 1p and 19q in the Diagnosis of Oligodendroglioma. A Study of Paraffin-Embedded Sections by Burger, Peter C., Minn, A. Yuriko, Smith, Justin S., Borell, Thomas J., Jedlicka, Anne E., Huntley, Brenda K., Goldthwaite, Patricia T., Jenkins, Robert B., Feuerstein, Burt G.

“…Comparative genomic hybridization (CGH), fluorescence in situ hybridization (FISH), polymerase chain reaction–based microsatellite analysis, and p53 sequencing…”
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Elevation of circulating but not myocardial FGF23 in human acute decompensated heart failure by Andersen, Ingrid A, Huntley, Brenda K, Sandberg, Sharon S, Heublein, Denise M, Burnett, Jr, John C

“…Elevated plasma fibroblast growth factor 23 (FGF23) is a prognostic marker in chronic kidney disease. Recently, FGF23 was reported to also be a predictive…”
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The Aging Heart, Myocardial Fibrosis, and its Relationship to Circulating C-Type Natriuretic Peptide by Sangaralingham, S. Jeson, Huntley, Brenda K, Martin, Fernando L, McKie, Paul M, Bellavia, Diego, Ichiki, Tomoko, Harders, Gerald E, Chen, Horng H, Burnett, John C

“…Myocardial aging is characterized by left ventricular (LV) fibrosis leading to diastolic and systolic dysfunction. Studies have established the potent…”
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Corin Is Present in the Normal Human Heart, Kidney, and Blood, with Pro-B-Type Natriuretic Peptide Processing in the Circulation by ICHIKI, Tomoko, HUNTLEY, Brenda K, HEUBLEIN, Denise M, SANDBERG, Sharon M, MCKIE, Paul M, MARTIN, Fernando L, JOUGASAKI, Michihisa, BURNETT, John C

“…B-type natriuretic peptide (BNP), which is activated in heart failure (HF), is processed to an active form by corin. The corin gene is expressed in the human…”
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Atrial Natriuretic Peptide Genetic Variant rs5065 and Risk for Cardiovascular Disease in the General Community: A 9-Year Follow-Up Study by Cannone, Valentina, Huntley, Brenda K, Olson, Timothy M, Heublein, Denise M, Scott, Christopher G, Bailey, Kent R, Redfield, Margaret M, Rodeheffer, Richard J, Burnett, John C

“…We analyzed the phenotype associated with the atrial natriuretic peptide (ANP) genetic variant rs5065 in a random community-based sample. We also assessed and…”
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Pro-Atrial Natriuretic Peptide: A Novel Guanylyl Cyclase-A Receptor Activator That Goes Beyond Atrial and B-Type Natriuretic Peptides by Ichiki, Tomoko, Huntley, Brenda K, Sangaralingham, S Jeson, Burnett, Jr, John C

“…The aim of this study was to determine if the atrial natriuretic peptide (ANP) precursor proANP is biologically active compared with ANP and B-type natriuretic…”
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PTEN Mutation, EGFR Amplification, and Outcome in Patients With Anaplastic Astrocytoma and Glioblastoma Multiforme by Smith, Justin S., Tachibana, Issei, Passe, Sandra M., Huntley, Brenda K., Borell, Thomas J., Iturria, Nancy, O'Fallon, Judith R., Schaefer, Paul L., Scheithauer, Bernd W., James, C. David, Buckner, Jan C., Jenkins, Robert B.

“…Background: Survival of patients with anaplastic astrocytoma is highly variable. Prognostic markers would thus be useful to identify clinical subsets of such…”
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