Search Results - "HUNTER, R. N"

Randomized Trial Comparing the Effects of Ticagrelor Versus Clopidogrel on Myocardial Perfusion in Patients With Coronary Artery Disease by Pelletier-Galarneau, Matthieu, Hunter, Chad R R N, Ascah, Kathryn J, Beanlands, Rob S B, Dwivedi, Girish, deKemp, Robert A, Chow, Benjamin J W, Ruddy, Terrence D

“…Ticagrelor is a P2Y receptor inhibitor used in acute coronary syndromes to reduce platelet activity and to decrease thrombus formation. Ticagrelor is…”
Get full text

Relationship of Mitotic Arrest and Apoptosis to Antitumor Effect of Paclitaxel by Milross, Christopher G., Mason, Kathryn A., Hunter, Nancy R., Chung, Woong-Ki, Peters, Lester J., Milas, Luka

“…Background Microtubules are cellular organelles with functions that include control of cell division by mitosis, cell morphology, and transport of material…”
Get full text

Inverse Relationship between Epidermal Growth Factor Receptor Expression and Radiocurability of Murine Carcinomas by AKIMOTO, T, HUNTER, N. R, BUCHMILLER, L, MASON, K, KIAN ANG, K, MILAS, L

“…The study investigated whether a relationship exists between the extent of epidermal growth factor receptor (EGFR) expression and in vivo radiocurability of…”
Get full text

Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis by Bramson, H. Neal, Corona, John, Davis, Stephen T, Dickerson, Scott H, Edelstein, Mark, Frye, Stephen V, Gampe, Robert T, Harris, Phil A, Hassell, Anne, Holmes, William D, Hunter, Robert N, Lackey, Karen E, Lovejoy, Brett, Luzzio, Michael J, Montana, Val, Rocque, Warren J, Rusnak, David, Shewchuk, Lisa, Veal, James M, Walker, Duncan H, Kuyper, Lee F

“…Two closely related classes of oxindole-based compounds, 1H-indole-2,3-dione 3-phenylhydrazones and 3-(anilinomethylene)-1,3-dihydro-2H-indol-2-ones, were…”
Get full text

Biodistribution and radiation dosimetry of 82Rb at rest and during peak pharmacological stress in patients referred for myocardial perfusion imaging by Hunter, Chad R. R. N., Hill, Jeremy, Ziadi, M. Cecilia, Beanlands, Rob S. B., deKemp, Robert A.

“…Purpose 82 Rb is an ultra-short-lived positron emitter used for myocardial blood flow quantification with PET imaging. The aim of this study was to quantify…”
Get full text

Docetaxel enhances tumor radioresponse in vivo by MASON, K. A, HUNTER, N. R, MILAS, M, ABBRUZZESE, J. L, MILAS, L

“…Although the radiosensitizing potential of paclitaxel has been investigated extensively in cancer treatment, a sister taxane, docetaxel, has been studied…”
Get full text

2-Amino-6-arylsulfonylbenzonitriles as Non-nucleoside Reverse Transcriptase Inhibitors of HIV-1 by Chan, Joseph H, Hong, Jean S, Hunter, Robert N, Orr, G. Faye, Cowan, Jill R, Sherman, Douglas B, Sparks, Steven M, Reitter, Barbara E, Andrews, C. Webster, Hazen, Richard J, St Clair, Marty, Boone, Lawrence R, Ferris, Rob G, Creech, Katrina L, Roberts, Grace B, Short, Steven A, Weaver, Kurt, Ott, Ronda J, Ren, Jingshan, Hopkins, Andrew, Stuart, David I, Stammers, David K

“…A series of 2-amino-5-arylthiobenzonitriles (1) was found to be active against HIV-1. Structural modifications led to the sulfoxides (2) and sulfones (3). The…”
Get full text

The discovery of potent cRaf1 kinase inhibitors by LACKEY, K, CORY, M, RUTKOWSKE, R. D, VEAL, J. M, WOOD, E. R, DAVIS, R, FRYE, S. V, HARRIS, P. A, HUNTER, R. N, JUNG, D. K, MCDONALD, O. B, MCNUTT, R. W, PEEL, M. R

“…A series of benzylidene-1H-indol-2-one (oxindole) derivatives was synthesized and evaluated as cRaf-1 kinase inhibitors. The key features of the molecules were…”
Get full text

Antitumor Activity of Poly(l-glutamic acid)-Paclitaxel on Syngeneic and Xenografted Tumors by CHUN LI, PRICE, J. E, MILAS, L, HUNTER, N. R, SHI KE, YU, D.-F, CHARNSANGAVEJ, C, WALLACE, S

“…Poly( l -glutamic acid)-paclitaxel (PG-TXL) is a new water-soluble paclitaxel derivative that has shown remarkable antitumor activity against both ovarian and…”
Get full text

The Withers Archive: Online Availability of H. Rodney Withers' Data by Thames, H. D., Hunter, N. R., Mason, K. A.

Get full text

The Withers archive: Online availability of rod Wither’s data by Thames, Howard D, Hunter, N.R, Mason, Kathy A

“…Abstract The contents of the lab notebooks of H.R. Withers have been digitized and stored as 23 excel files, a total of approximately 45 megabytes. A procedure…”
Get full text

Maximizing therapeutic gain with gemcitabine and fractionated radiation by Mason, K A, Milas, L, Hunter, N R, Elshaikh, M, Buchmiller, L, Kishi, K, Hittelman, K, Ang, K K

“…The nucleoside analogue gemcitabine inhibits cellular repair and repopulation, induces apoptosis, causes tumor growth delay, and enhances radiation-induced…”
Get more information

Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies by Meyn, R E, Stephens, L C, Ang, K K, Hunter, N R, Brock, W A, Milas, L, Peters, L J

“…Fifteen different murine tumours were evaluated with respect to the degree of apoptosis development that occurs in the tumour tissue in the first few hours…”
Get more information

Role of reoxygenation in induction of enhancement of tumor radioresponse by Paclitaxel by MILAS, L, HUNTER, N. R, MASON, K. A, MILROSS, C. G, SAITO, Y, PETERS, L. J

“…We reported previously (L. Milas et al., Cancer Res., 54: 3506-3510, 1994) that paclitaxel greatly enhances the response of a murine mammary carcinoma to…”
Get full text

Development of Apoptosis in Irradiated Murine Tumors as a Function of Time and Dose by Stephens, L. Clifton, Hunter, Nancy R., Ang, K. Kian, Milas, Luka, Meyn, Raymond E.

“…In a previous paper (Radiat. Res. 127, 308-316, 1991), we reported that a moderately radiosensitive, transplantable murine ovarian carcinoma (OCaI) displayed…”
Get full text

Enhancement of tumor radioresponse of a murine mammary carcinoma by paclitaxel by MILAS, L, HUNTER, N. R, MASON, K. A, BELMA KURDOGLU, PETERS, L. J

“…Paclitaxel is a chemotherapeutic agent with potent microtubule stabilizing activity that arrests cells in G2-M. Because G2 and M are the most radiosensitive…”
Get full text

Crystallographic preferred orientation of quartz deformed at granulite conditions: the Kalinjala Shear Zone, Port Neill, South Australia by Wilson, C. J. L., Hunter, N. J. R., Luzin, V.

“…Crystallographic preferred orientations of quartz aggregates in mylonitic orthogneisses from the highest strained central region of the Kalinjala Shear Zone,…”
Get full text

Heat-shock protein 65 as a beta cell antigen of insulin-dependent diabetes by Jones, D B, Hunter, N R, Duff, G W

“…The primary beta-cell antigen of insulin-dependent diabetes is thought to be a protein with a molecular weight of approximately 64 kD. Hyperthermic incubation…”
Get more information

Large‐Scale Rotational Motion Within the Main Central Thrust Zone in the Darjeeling‐Sikkim Himalaya, India by Roberts, A. G., Weinberg, R. F., Hunter, N. J. R., Ganade, C. E.

“…Much of the shortening associated with the India‐Eurasia collision has been accommodated by orogen‐spanning shear zones within the fold‐and‐thrust belt that…”
Get full text

Apoptosis in murine tumors treated with chemotherapy agents by Meyn, R E, Stephens, L C, Hunter, N R, Milas, L

“…There is increasing attention directed to the hypothesis that apoptosis plays a role in the response to cancer treatment including chemotherapy. However, the…”
Get more information