Search Results - "HUNTER, L"
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Tuberculosis as a three-act play: A new paradigm for the pathogenesis of pulmonary tuberculosis
Published in Tuberculosis (Edinburgh, Scotland) (01-03-2016)“…Summary Lack of access to human tissues with untreated tuberculosis (TB) has forced generations of researchers to use animal models and to adopt a paradigm…”
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The Pathogenesis of Tuberculosis: The Early Infiltrate of Post-primary (Adult Pulmonary) Tuberculosis: A Distinct Disease Entity
Published in Frontiers in immunology (19-09-2018)“…It has long been recognized that tuberculosis (TB) induces both protective and tissue damaging immune responses. This paper reviews nearly two centuries of…”
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3
Coordinated integrin activation by actin-dependent force during T-cell migration
Published in Nature communications (10-10-2016)“…For a cell to move forward it must convert chemical energy into mechanical propulsion. Force produced by actin polymerization can generate traction across the…”
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4
The physics of the colloidal glass transition
Published in Reports on progress in physics (01-06-2012)“…As one increases the concentration of a colloidal suspension, the system exhibits a dramatic increase in viscosity. Beyond a certain concentration, the system…”
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Pathology of post primary tuberculosis of the lung: An illustrated critical review
Published in Tuberculosis (Edinburgh, Scotland) (01-11-2011)“…Summary Post primary tuberculosis occurs in immunocompetent adults, is restricted to the lungs and accounts for 80% of all clinical cases and nearly 100% of…”
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Quantitative Mass Spectrometric Multiple Reaction Monitoring Assays for Major Plasma Proteins
Published in Molecular & cellular proteomics (01-04-2006)“…Quantitative LC-MS/MS assays were designed for tryptic peptides representing 53 high and medium abundance proteins in human plasma using a multiplexed multiple…”
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Global association of air pollution and heart failure: a systematic review and meta-analysis
Published in The Lancet (British edition) (21-09-2013)“…Summary Background Acute exposure to air pollution has been linked to myocardial infarction, but its effect on heart failure is uncertain. We did a systematic…”
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Macrophage heterogeneity and plasticity in tuberculosis
Published in Journal of leukocyte biology (01-08-2019)“…Macrophages are the primary host cells for Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), during its intracellular survival in humans…”
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Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
Published in Nature medicine (01-03-2009)“…During autophagy, cytosolic proteins and damaged organelles are delivered via autophagosomes to lysosomes, where they are degraded before presentation at the…”
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Human-interpretable image features derived from densely mapped cancer pathology slides predict diverse molecular phenotypes
Published in Nature communications (12-03-2021)“…Computational methods have made substantial progress in improving the accuracy and throughput of pathology workflows for diagnostic, prognostic, and genomic…”
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11
A direct GABAergic output from the basal ganglia to frontal cortex
Published in Nature (London) (07-05-2015)“…Anatomical and functional analyses reveal the existence of two types of globus pallidus externus neurons that directly control cortex, suggesting a pathway by…”
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12
Purkinje Cells Directly Inhibit Granule Cells in Specialized Regions of the Cerebellar Cortex
Published in Neuron (Cambridge, Mass.) (21-09-2016)“…Inhibition of granule cells plays a key role in gating the flow of signals into the cerebellum, and it is thought that Golgi cells are the only interneurons…”
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Echocardiographic Findings in Pediatric Multisystem Inflammatory Syndrome Associated With COVID-19 in the United States
Published in Journal of the American College of Cardiology (27-10-2020)“…Centers from Europe and United States have reported an exceedingly high number of children with a severe inflammatory syndrome in the setting of coronavirus…”
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14
Progression of elite sport through technology is a fait accompli ; the line should be drawn from the start
Published in Journal of applied physiology (1985) (01-09-2024)Get full text
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15
Extended high-frequency hearing enhances speech perception in noise
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2019)“…Young healthy adults can hear tones up to at least 20 kHz. However, clinical audiometry, by which hearing loss is diagnosed, is limited at high frequencies to…”
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Conserved associations between G-quadruplex-forming DNA motifs and virulence gene families in malaria parasites
Published in BMC genomics (17-03-2020)“…The Plasmodium genus of malaria parasites encodes several families of antigen-encoding genes. These genes tend to be hyper-variable, highly recombinogenic and…”
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The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability
Published in Nature neuroscience (01-05-2016)“…This study identifies SFPQ (splicing factor, poly-glutamine rich) as an RNA binding protein that binds and coassembles multiple mRNAs in axonal transport…”
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Using geoelectrons to search for velocity-dependent spin-spin interactions
Published in Physical review letters (07-03-2014)“…We use the recently developed model of the electron spins within Earth to investigate all of the six possible long-range velocity-dependent spin-spin…”
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Broad threat to humanity from cumulative climate hazards intensified by greenhouse gas emissions
Published in Nature climate change (01-12-2018)“…The ongoing emission of greenhouse gases (GHGs) is triggering changes in many climate hazards that can impact humanity. We found traceable evidence for 467…”
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ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex
Published in Molecular cell (18-03-2011)“…Cell movement begins with a leading edge protrusion, which is stabilized by nascent adhesions and retracted by mature adhesions. The ERK-MAPK (extracellular…”
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