Search Results - "HUNTER, Daniel A"

Increasing Nerve Autograft Length Increases Senescence and Reduces Regeneration by Hoben, Gwendolyn M., Ee, Xueping, Schellhardt, Lauren, Yan, Ying, Hunter, Daniel A., Moore, Amy M., Snyder-Warwick, Alison K., Stewart, Sheila, Mackinnon, Susan E., Wood, Matthew D.

“…BACKGROUND:Nerve grafting with an autograft is considered the gold standard. However, the functional outcomes of long (>3 cm) nerve autografting are often…”
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Acellular nerve allografts in peripheral nerve regeneration: A comparative study by Moore, Amy M., Macewan, Matthew, Santosa, Katherine B., Chenard, Kristofer E., Ray, Wilson Z., Hunter, Daniel A., Mackinnon, Susan E., Johnson, Philip J.

“…Introduction: Processed nerve allografts offer a promising alternative to nerve autografts in the surgical management of peripheral nerve injuries where short…”
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Electrical stimulation or tacrolimus (FK506) alone enhances nerve regeneration and recovery after nerve surgery, while dual use reduces variance and combines strengths of each in promoting enhanced outcomes by Marsh, Evan B., Schellhardt, Lauren, Hunter, Daniel A., Mackinnon, Susan E., Snyder‐Warwick, Alison K., Wood, Matthew D.

“…Introduction/Aims Repaired nerve injuries can fail to achieve functional recovery. Therapeutic options beyond surgery, such as systemic tacrolimus (FK506) and…”
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Limited Nerve Regeneration across Acellular Nerve Allografts (ANAs) Coincides with Changes in Blood Vessel Morphology and the Development of a Pro-Inflammatory Microenvironment by Acevedo Cintrón, Jesús A, Hunter, Daniel A, Schellhardt, Lauren, Pan, Deng, Mackinnon, Susan E, Wood, Matthew D

“…The use of acellular nerve allografts (ANAs) to reconstruct long nerve gaps (>3 cm) is associated with limited axon regeneration. To understand why ANA length…”
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Processed allografts and type I collagen conduits for repair of peripheral nerve gaps by Whitlock, Elizabeth L., Tuffaha, Sami H., Luciano, Janina P., Yan, Ying, Hunter, Daniel A., Magill, Christina K., Moore, Amy M., Tong, Alice Y., Mackinnon, Susan E., Borschel, Gregory H.

“…Autografting is the gold standard in the repair of peripheral nerve injuries that are not amenable to end‐to‐end coaptation. However, because autografts result…”
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Mechanism-based combination treatment dramatically increases therapeutic efficacy in murine globoid cell leukodystrophy by Hawkins-Salsbury, Jacqueline A, Shea, Lauren, Jiang, Xuntian, Hunter, Daniel A, Guzman, A Miguel, Reddy, Adarsh S, Qin, Elizabeth Y, Li, Yedda, Gray, Steven J, Ory, Daniel S, Sands, Mark S

“…Globoid cell leukodystrophy (GLD, Krabbe disease) is a lysosomal storage disease (LSD) caused by a deficiency in galactocerebrosidase (GALC) activity. In the…”
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Axonal Growth Arrests After an Increased Accumulation of Schwann Cells Expressing Senescence Markers and Stromal Cells in Acellular Nerve Allografts by Poppler, Louis H, Ee, Xueping, Schellhardt, Lauren, Hoben, Gwendolyn M, Pan, Deng, Hunter, Daniel A, Yan, Ying, Moore, Amy M, Snyder-Warwick, Alison K, Stewart, Sheila A, Mackinnon, Susan E, Wood, Matthew D

“…Acellular nerve allografts (ANAs) and other nerve constructs do not reliably facilitate axonal regeneration across long defects (>3 cm). Causes for this…”
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Schwann cells seeded in acellular nerve grafts improve functional recovery by Jesuraj, Nithya J., Santosa, Katherine B., Macewan, Matthew R., Moore, Amy M., Kasukurthi, Rahul, Ray, Wilson Z., Flagg, Eric R., Hunter, Daniel A., Borschel, Gregory H., Johnson, Philip J., Mackinnon, Susan E., Sakiyama-Elbert, Shelly E.

“…ABSTRACT Introduction: This study evaluated whether Schwann cells (SCs) from different nerve sources transplanted into cold‐preserved acellular nerve grafts…”
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Affinity-based release of glial-derived neurotrophic factor from fibrin matrices enhances sciatic nerve regeneration by Wood, Matthew D., Moore, Amy M., Hunter, Daniel A., Tuffaha, Sami, Borschel, Gregory H., Mackinnon, Susan E., Sakiyama-Elbert, Shelly E.

“…Glial-derived neurotrophic factor (GDNF) promotes both sensory and motor neuron survival. The delivery of GDNF to the peripheral nervous system has been shown…”
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Effects of motor versus sensory nerve grafts on peripheral nerve regeneration by Nichols, Chris M., Brenner, Michael J., Fox, Ida K., Tung, Thomas H., Hunter, Daniel A., Rickman, Susan R., Mackinnon, Susan E.

“…Autologous nerve grafting is the current standard of care for nerve injuries resulting in a nerve gap. This treatment requires the use of sensory grafts to…”
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Controlled release of nerve growth factor enhances sciatic nerve regeneration by Lee, Annie C, Yu, Vivian M, Lowe, James B, Brenner, Michael J, Hunter, Daniel A, Mackinnon, Susan E, Sakiyama-Elbert, Shelly E

“…Based on previous studies demonstrating the potential of growth factors to enhance peripheral nerve regeneration, we developed a novel growth factor delivery…”
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Axotomy or compression is required for axonal sprouting following end-to-side neurorrhaphy by Hayashi, Ayato, Pannucci, Christopher, Moradzadeh, Arash, Kawamura, David, Magill, Christina, Hunter, Daniel A., Tong, Alice Y., Parsadanian, Alexander, Mackinnon, Susan E., Myckatyn, Terence M.

“…End-to-side (ETS) nerve repair remains an area of intense scrutiny for peripheral nerve surgeon-scientists. In this technique, the transected end of an injured…”
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High Figure‐of‐Merit Gallium Oxide UV Photodetector on Silicon by Molecular Beam Epitaxy: A Path toward Monolithic Integration by Mukhopadhyay, Partha, Hatipoglu, Isa, Sakthivel, Tamil Selvan, Hunter, Daniel A., Edwards, Paul R., Martin, Robert W., Naresh-Kumar, Gunasekar, Seal, Sudipta, Schoenfeld, Winston V.

“…A high figure‐of‐merit UV‐C solar‐blind photodetector (PD) fabricated from thin‐film beta‐gallium oxide (β‐Ga2O3) grown on n‐Si substrates by plasma‐assisted…”
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Motor Neuron Regeneration through End-to-Side Repairs Is a Function of Donor Nerve Axotomy by Brenner, Michael J., Dvali, Linda, Hunter, Daniel A., Myckatyn, Terence M., Mackinnon, Susan E.

“…Over the past decade, a growing body of literature has emerged supporting the use of end-to-side (terminolateral) neurorrhaphy for the treatment of selected…”
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Controlled Delivery of Glial Cell Line–Derived Neurotrophic Factor Enhances Motor Nerve Regeneration by Moore, Amy M., MD, Wood, Matthew D., PhD, Chenard, Kristopher, BS, Hunter, Daniel A., RA, Mackinnon, Susan E., MD, Sakiyama-Elbert, Shelly E., PhD, Borschel, Gregory H., MD

“…Purpose To determine the effect of a motor-specific neurotrophic factor, glial-derived neurotrophic factor (GDNF) on motor nerve regeneration. Methods We used…”
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Investigating Susceptibility to Diabetes Using Features of the Adipose Tissue in Response to In Utero Polycyclic Aromatic Hydrocarbons Exposure by Gato, Worlanyo E, Hunter, Daniel A, Whitby, Shamaya L, Mays, Christopher A, Yau, Wilson

“…In recent times, there has been an increase in the incidence of type 2 diabetes mellitus (T2DM) particularly in children. Adipocyte dysfunction provide a…”
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Comparing electrical stimulation and tacrolimus (FK506) to enhance treating nerve injuries by Jo, Sally, Pan, Deng, Halevi, Alexandra E., Roh, Joseph, Schellhardt, Lauren, Hunter RA, Daniel A., Snyder‐Warwick, Alison K., Moore, Amy M., Mackinnon, Susan E., Wood, Matthew D.

“…Introduction Neuroenhancing therapies are desired because repair of nerve injuries can fail to achieve recovery. We compared two neuroenhancing therapies,…”
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Fibrin glue mitigates the learning curve of microneurosurgical repair by Whitlock, Elizabeth L., Kasukurthi, Rahul, Yan, Ying, Tung, Thomas H., Hunter, Daniel A., Mackinnon, Susan E.

“…Microneurosurgical technique has a steep learning curve. An alternative to microepineurial suture repair of peripheral nerves that circumvents this learning…”
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Response: Investigating Susceptibility to Diabetes Using Features of the Adipose Tissue in Response to In Utero Polycyclic Aromatic Hydrocarbons Exposure (Diabetes Metab J 2016;40:494-508) by Gato, Worlanyo E, Hunter, Daniel A, Whitby, Shamaya L, Mays, Christopher A, Yau, Wilson

“…KCI Citation Count: 0…”
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Limited regeneration in long acellular nerve allografts is associated with increased Schwann cell senescence by Saheb-Al-Zamani, Maryam, Yan, Ying, Farber, Scott J., Hunter, Daniel A., Newton, Piyaraj, Wood, Matthew D., Stewart, Sheila A., Johnson, Philip J., Mackinnon, Susan E.

“…Repair of large nerve defects with acellular nerve allografts (ANAs) is an appealing alternative to autografting and allotransplantation. ANAs have been shown…”
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