Search Results - "HUNTER, DAVID J."

Osteoarthritis in 2020 and beyond: a Lancet Commission by Hunter, David J, March, Lyn, Chew, Mabel

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Uncertainty in the Era of Precision Medicine by Hunter, David J

“…Far from ushering in an age of diagnostic and prognostic certainty, precision-medicine tools will demand a greater tolerance of uncertainty and greater…”
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Pharmacologic therapy for osteoarthritis-the era of disease modification by Hunter, David J

“…Current therapeutic strategies for osteoarthritis (OA) are mostly palliative; modifying the structural progression of OA has, therefore, become a focus of drug…”
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The individual and socioeconomic impact of osteoarthritis by Hunter, David J., Schofield, Deborah, Callander, Emily

“…Osteoarthritis (OA) is an important cause of disability worldwide, and its impact is growing rapidly. In this Opinion article, the authors draw attention to…”
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Post-traumatic osteoarthritis: from mouse models to clinical trials by Little, Christopher B., Hunter, David J.

“…In this Review, Little and Hunter discuss the use of animal models in osteoarthritis (OA) research, focusing on their importance in understanding…”
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Platelet-Rich Plasma for the Management of Hip and Knee Osteoarthritis by Bennell, Kim L., Hunter, David J., Paterson, Kade L.

“…Purpose of Review Knee and hip osteoarthritis (OA) are major public health problems worldwide causing pain, disability and impaired quality of life. This…”
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Hip Osteoarthritis: Etiopathogenesis and Implications for Management by Murphy, Nicholas J., Eyles, Jillian P., Hunter, David J.

“…Highly prevalent among the elderly, hip osteoarthritis (OA) carries a heavy burden of disease. Guidelines for the management of hip OA are often extrapolated…”
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Efficacy, Safety, and Accuracy of Intra-articular Therapies for Hand Osteoarthritis: Current Evidence by Oo, Win Min, Hunter, David J.

“…The lifetime risk of symptomatic hand osteoarthritis (OA) is 39.8%, with one in two women and one in four men developing the disease by age 85 years and no…”
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The Development of Disease-Modifying Therapies for Osteoarthritis (DMOADs): The Evidence to Date by Oo, Win Min, Little, Christopher, Duong, Vicky, Hunter, David J

“…Osteoarthritis (OA) is a complex heterogeneous articular disease with multiple joint tissue involvement of varying severity and no regulatory-agency-approved…”
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Repurposed and investigational disease-modifying drugs in osteoarthritis (DMOADs) by Oo, Win Min, Hunter, David J.

“…In spite of a major public health burden with increasing prevalence, current osteoarthritis (OA) management is largely palliative with an unmet need for…”
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Predictive validity of biochemical biomarkers in knee osteoarthritis: data from the FNIH OA Biomarkers Consortium by Kraus, Virginia Byers, Collins, Jamie E, Hargrove, David, Losina, Elena, Nevitt, Michael, Katz, Jeffrey N, Wang, Susanne X, Sandell, Linda J, Hoffmann, Steven C, Hunter, David J

“…To investigate a targeted set of biochemical biomarkers as predictors of clinically relevant osteoarthritis (OA) progression. Eighteen biomarkers were measured…”
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Technology-assisted rehabilitation following total knee or hip replacement for people with osteoarthritis: a systematic review and meta-analysis by Wang, Xia, Hunter, David J, Vesentini, Giovana, Pozzobon, Daniel, Ferreira, Manuela L

“…To evaluate the effectiveness and safety of technology-assisted rehabilitation following total hip/knee replacement (THR/TKR). Six electronic databases were…”
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Pharmacodynamics, efficacy, safety and administration of intra-articular therapies for knee osteoarthritis by Oo, Win Min, Liu, Xiaoqian, Hunter, David J

“…: Osteoarthritis (OA) is the leading cause of disability in the elderly, usually presenting with mono-or oligo-arthritis where local drug delivery by…”
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Population Attributable Risk of Modifiable and Nonmodifiable Breast Cancer Risk Factors in Postmenopausal Breast Cancer by Tamimi, Rulla M, Spiegelman, Donna, Smith-Warner, Stephanie A, Wang, Molin, Pazaris, Mathew, Willett, Walter C, Eliassen, A Heather, Hunter, David J

“…We examined the proportions of multiple types of breast cancers in the population that were attributable to established risk factors, focusing on behaviors…”
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What Comes First? Multitissue Involvement Leading to Radiographic Osteoarthritis: Magnetic Resonance Imaging–Based Trajectory Analysis Over Four Years in the Osteoarthritis Initiative by Roemer, Frank W., Kwoh, C. Kent, Hannon, Michael J., Hunter, David J., Eckstein, Felix, Fujii, Tomoko, Boudreau, Robert M., Guermazi, Ali

“…Objective To assess whether the presence of structural osteoarthritis (OA) features over as many as 4 years prior to incident radiographic OA increases the…”
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Powerful SNP-Set Analysis for Case-Control Genome-wide Association Studies by Wu, Michael C., Kraft, Peter, Epstein, Michael P., Taylor, Deanne M., Chanock, Stephen J., Hunter, David J., Lin, Xihong

“…GWAS have emerged as popular tools for identifying genetic variants that are associated with disease risk. Standard analysis of a case-control GWAS involves…”
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Letting the Genome out of the Bottle — Will We Get Our Wish? by Hunter, David J, Khoury, Muin J, Drazen, Jeffrey M

“…A patient shows up in your office with an analysis of his whole genome at multiple single-nucleotide polymorphisms (SNPs). What should you do? Drs. David…”
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Use of Tanning Beds and Incidence of Skin Cancer by MINGFENG ZHANG, QURESHI, Abrar A, GELLER, Alan C, FRAZIER, Lindsay, HUNTER, David J, JIALI HAN

“…We sought to evaluate the risk effect of tanning bed use on skin cancers among teenage and young adults. We also expected to determine whether a dose-response…”
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Investigating the impact of innovative AI chatbot on post‐pandemic medical education and clinical assistance: a comprehensive analysis by Xie, Yi, Seth, Ishith, Hunter‐Smith, David J., Rozen, Warren M., Seifman, Marc A.

“…Background The COVID‐19 pandemic has significantly disrupted clinical experience and exposure of medical students and junior doctors. Artificial Intelligence…”
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Cherry consumption and decreased risk of recurrent gout attacks by Zhang, Yuqing, Neogi, Tuhina, Chen, Clara, Chaisson, Christine, Hunter, David J., Choi, Hyon K.

“…Objective To study the relationship between cherry intake and the risk of recurrent gout attacks among individuals with gout. Methods We conducted a…”
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