Search Results - "HUMPERT, Per"

A novel nutritional supplement containing amino acids and chromium decreases postprandial glucose response in a randomized, double-blind, placebo-controlled study by Ostman, Elin, Samigullin, Azat, Heyman-Linden, Lovisa, Andersson, Kristina, Bjorck, Inger, Oste, Rickard, Humpert, Per M, de Souza, Russell J

“…High postprandial blood glucose levels are associated with increased mortality, cardiovascular events and development of diabetes in the general population…”
Get full text

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart by ANDRASSY, Martin, VOLZ, Hans C, BEA, Florian, HARDT, Stefan E, HUMPERT, Per M, BIANCHI, Marco E, MAIRBÄURL, Heimo, NAWROTH, Peter P, REMPPIS, Andrew, KATUS, Hugo A, BIERHAUS, Angelika, IGWE, John C, FUNKE, Benjamin, EICHBERGER, Sebastian N, KAYA, Ziya, BUSS, Sebastian, AUTSCHBACH, Frank, PLEGER, Sven T, LUKIC, Ivan K

“…High-mobility group box-1 (HMGB1) is a nuclear factor released by necrotic cells and by activated immune cells. HMGB1 signals via members of the toll-like…”
Get full text

Understanding RAGE, the receptor for advanced glycation end products by BIERHAUS, Angelika, HUMPERT, Per M, MORCOS, Michael, WENDT, Thoralf, CHAVAKIS, Triantafyllos, ARNOLD, Bernd, STERN, David M, NAWROTH, Peter P

“…Advanced glycation end products (AGEs), S100/calgranulins, HMGB1-proteins, amyloid-beta peptides, and the family of beta-sheet fibrils have been shown to…”
Get full text

Postprandial Symptoms in a Mixed-Meal-Test after Bariatric Surgery - Clinical Experience and a Critical Review of Dumping Syndrome Definition and Management by Samigullin, Azat, Weihrauch, Julia, Otto, Mirko, Rech, Andrea, Buchenberger, Sandra, Morcos, Michael, Humpert, Per M

“…Introduction Despite recent attempts to reach a consensus on the diagnostic criteria and treatment of Dumping Syndrome (DS) after bariatric surgery, many…”
Get full text

Urinary Liver-Type Fatty Acid-Binding Protein and Progression of Diabetic Nephropathy in Type 1 Diabetes by PANDURU, Nicolae M, FORSBLOM, Carol, SARAHEIMO, Markku, THORN, Lena, BIERHAUS, Angelika, HUMPERT, Per M, GROOP, Per-Henrik

“…Diabetic nephropathy (DN) has mainly been considered a glomerular disease, although tubular dysfunction may also play a role. This study assessed the…”
Get full text

Sustained Effects of a Mindfulness-Based Stress-Reduction Intervention in Type 2 Diabetic Patients: Design and first results of a randomized controlled trial (the Heidelberger Diabetes and Stress-Study) by Hartmann, Mechthild, Kopf, Stefan, Kircher, Claudia, Faude-Lang, Verena, Djuric, Zdenka, Augstein, Florian, Friederich, Hans-Christoph, Kieser, Meinhard, Bierhaus, Angelika, Humpert, Per M, Herzog, Wolfgang, Nawroth, Peter P

“…OBJECTIVE: To determine whether a mindfulness-based stress reduction (MBSR) intervention is effective for reducing psychosocial distress (i.e., depression,…”
Get full text

Kidney injury molecule-1 and the loss of kidney function in diabetic nephropathy: a likely causal link in patients with type 1 diabetes by Panduru, Nicolae M, Sandholm, Niina, Forsblom, Carol, Saraheimo, Markku, Dahlström, Emma H, Thorn, Lena M, Gordin, Daniel, Tolonen, Nina, Wadén, Johan, Harjutsalo, Valma, Bierhaus, Angelika, Humpert, Per M, Groop, Per-Henrik

“…We evaluated the predictive value and clinical benefit of urinary kidney injury molecule (KIM)-1 for progression of diabetic nephropathy (DN) in type 1…”
Get full text

Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque by Korosoglou, Grigorios, Lehrke, Stephanie, Mueller, Dirk, Hosch, Waldemar, Kauczor, Hans-Ulrich, Humpert, Per M, Giannitsis, Evangelos, Katus, Hugo A

“…To understand the determinants of troponin release in patients with stable coronary artery disease (CAD) by comparing high sensitive troponin T (hsTnT) levels…”
Get more information

Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process: a mini-review by Fleming, Thomas H, Humpert, Per M, Nawroth, Peter P, Bierhaus, Angelika

“…Aging is a dynamic process in which its rate and subsequent longevity of an organism are dependent upon the balance between the reactive intermediates of…”
Get more information

Continuous glucose monitoring as a close to real life alternative to meal studies – a pilot study with a functional drink containing amino acids and chromium by Samigullin, Azat, Humpert, Per M., Östman, Elin

“…This pilot study aimed to evaluate a continuous glucose monitoring (CGM) based approach to study the effects of a functional drink containing specific amino…”
Get full text

C. elegans as Model for the Study of High Glucose– Mediated Life Span Reduction by SCHLOTTERER, Andreas, KUKUDOV, Georgi, SAYED, Ahmed, FLEMING, Thomas, HUMPERT, Per, SCHWENGER, Vedat, ZEIER, Martin, HAMANN, Andreas, STERN, David, BROWNLEE, Michael, BIERHAUS, Angelika, NAWROTH, Peter, BOZORGMEHR, Farastuk, MORCOS, Michael, HUTTER, Harald, XUELIANG DU, OIKONOMOU, Dimitrios, IBRAHIM, Youssef, PFISTERER, Friederike, RABBANI, Naila, THORNALLEY, Paul

“…C. elegans as Model for the Study of High Glucose– Mediated Life Span Reduction Andreas Schlotterer 1 , Georgi Kukudov 1 , Farastuk Bozorgmehr 1 , Harald…”
Get full text

A Mechanism Converting Psychosocial Stress into Mononuclear Cell Activation by Bierhaus, Angelika, Wolf, Jutta, Andrassy, Martin, Rohleder, Nicolas, Humpert, Per M., Petrov, Dimitri, Ferstl, Roman, von Eynatten, Maximilian, Wendt, Thoralf, Rudofsky, Gottfried, Joswig, Martina, Morcos, Michael, Schwaninger, Markus, McEwen, Bruce, Kirschbaum, Clemens, Nawroth, Peter P.

“…Little is known about the mechanisms converting psychosocial stress into cellular dysfunction. Various genes, up-regulated in atherosclerosis but also by…”
Get full text

Urinary adiponectin is an independent predictor of progression to end-stage renal disease in patients with type 1 diabetes and diabetic nephropathy by Panduru, Nicolae M, Saraheimo, Markku, Forsblom, Carol, Thorn, Lena M, Gordin, Daniel, Wadén, Johan, Tolonen, Nina, Bierhaus, Angelika, Humpert, Per M, Groop, Per-Henrik

“…We investigated the predictive value of urinary adiponectin (uADP) for the progression of diabetic nephropathy (DN) as well as for the principal determinants…”
Get full text

Proximal Neuropathic Lesions in Distal Symmetric Diabetic Polyneuropathy: Findings of high-resolution magnetic resonance neurography by Pham, Mirko, Oikonomou, Dimitrios, Bäumer, Philipp, Bierhaus, Angelika, Heiland, Sabine, Humpert, Per M, Nawroth, Peter P, Bendszus, Martin

“…OBJECTIVE: This study investigated high-resolution magnetic resonance neurography (MRN) in distal symmetric diabetic polyneuropathy (dPNP). RESEARCH DESIGN AND…”
Get full text

Urinary liver-type fatty acid binding protein is an independent predictor of stroke and mortality in individuals with type 1 diabetes by Panduru, Nicolae M., Forsblom, Carol, Saraheimo, Markku, Thorn, Lena M., Gordin, Daniel, Elonen, Nina, Harjusalo, Valma, Bierhaus, Angelika, Humpert, Per M., Groop, Per-Henrik

“…Aims/hypothesis In type 1 diabetes, cardiovascular disease (CVD) and diabetic nephropathy progress in parallel, thereby potentiating the risk of premature…”
Get full text

Dietary Intervention with Oatmeal in Patients with uncontrolled Type 2 Diabetes Mellitus - A Crossover Study by Delgado, Graciela, Kleber, Marcus E, Krämer, Bernhard K, Morcos, Michael, Humpert, Per M, Wiegand, Kerstin, Mauldin, Andy, Kusterer, Klaus, Enghöfer, Michael, März, Winfried, Segiet, Thomas, Lammert, Alexander

“…In a pilot study, we evaluated the efficacy of two days of oatmeal on insulin resistance and glucose metabolism and found a marked decrease of insulin…”
Get more information

Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes by Humpert, Per M, Djuric, Zdenka, Kopf, Stefan, Rudofsky, Gottfried, Morcos, Michael, Nawroth, Peter P, Bierhaus, Angelika

“…Total circulating soluble receptor for advanced glycation endproducts (sRAGE) and a more defined endogenous secretory splice variant of the receptor (esRAGE)…”
Get full text

Left ventricular diastolic function in type 2 diabetes mellitus is associated with myocardial triglyceride content but not with impaired myocardial perfusion reserve by Korosoglou, Grigorios, Humpert, Per M., Ahrens, Johannes, Oikonomou, Dimitrios, Osman, Nael F., Gitsioudis, Gitsios, Buss, Sebastian J., Steen, Henning, Schnackenburg, Bernhardt, Bierhaus, Angelika, Nawroth, Peter P., Katus, Hugo A.

“…Purpose: To study myocardial perfusion reserve and myocellular metabolic alterations indicated by triglyceride content as possible causes of diastolic…”
Get full text

Glyoxalase‐1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans by Morcos, Michael, Du, Xueliang, Pfisterer, Friederike, Hutter, Harald, Sayed, Ahmed A. R., Thornalley, Paul, Ahmed, Naila, Baynes, John, Thorpe, Suzanne, Kukudov, Georgi, Schlotterer, Andreas, Bozorgmehr, Farastuk, El Baki, Randa Abd, Stern, David, Moehrlen, Frank, Ibrahim, Youssef, Oikonomou, Dimitrios, Hamann, Andreas, Becker, Christian, Zeier, Martin, Schwenger, Vedat, Miftari, Nexhat, Humpert, Per, Hammes, Hans‐Peter, Buechler, Markus, Bierhaus, Angelika, Brownlee, Michael, Nawroth, Peter P.

“…Summary Studies of mutations affecting lifespan in Caenorhabditis elegans show that mitochondrial generation of reactive oxygen species (ROS) plays a major…”
Get full text

Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB by BIERHAUS, Angelika, SCHIEKOFER, Stephan, MORCOS, Michael, HOFMANN, Marion, TRITSCHLER, Hans, WEIGLE, Bernd, KASPER, Michael, SMITH, Mark, PERRY, George, SCHMIDT, Ann-Marie, STERN, David M, HÄRING, Hans-Ulrich, SCHWANINGER, Markus, SCHLEICHER, Erwin, NAWROTH, Peter P, ANDRASSY, Martin, HUMPERT, Per M, JIANG CHEN, MEI HONG, LUTHER, Thomas, HENLE, Thomas, KLÖTING, Ingrid

“…Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB Angelika Bierhaus 1 2 , Stephan Schiekofer 1 2 , Markus Schwaninger 1 ,…”
Get full text