Search Results - "HUMME, Sibille"

Recent developments in adeno-associated virus vector technology by Büning, Hildegard, Perabo, Luca, Coutelle, Oliver, Quadt-Humme, Sibille, Hallek, Michael

“…Adeno‐associated virus (AAV), a single‐stranded DNA parvovirus, is emerging as one of the leading gene therapy vectors owing to its nonpathogenicity and low…”
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B cell receptor signal strength determines B cell fate by Casola, Stefano, Rajewsky, Klaus, Otipoby, Kevin L, Alimzhanov, Marat, Humme, Sibille, Uyttersprot, Nathalie, Kutok, Jeffery L, Carroll, Michael C

“…B cell receptor (BCR)-mediated antigen recognition is thought to regulate B cell differentiation. BCR signal strength may also influence B cell fate decisions…”
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Heparan Sulfate Proteoglycan Binding Properties of Adeno-Associated Virus Retargeting Mutants and Consequences for Their In Vivo Tropism by PERABO, Luca, GOLDNAU, Daniela, BÜNING, Hildegard, WHITE, Kathryn, ENDELL, Jan, BOUCAS, Jorge, HUMME, Sibille, WORK, Lorraine M, JANICKI, Hanna, HALLEK, Michael, BAKER, Andrew H

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The EBV Nuclear Antigen 1 (EBNA1) Enhances B Cell Immortalization Several Thousandfold by Humme, Sibille, Reisbach, Gilbert, Feederle, Regina, Delecluse, Henri-Jacques, Bousset, Kristine, Hammerschmidt, Wolfgang, Schepers, Aloys

“…The Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is one of the earliest viral proteins expressed after infection and is the only latent protein…”
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Engineering adeno-associated virus serotype 2-based targeting vectors using a new insertion site-position 453-and single point mutations by Boucas, Jorge, Lux, Kerstin, Huber, Anke, Schievenbusch, Stephanie, von Freyend, Miriam John, Perabo, Luca, Quadt-Humme, Sibille, Odenthal, Margarete, Hallek, Michael, Büning, Hildegard

“…Background Genetic modification of capsid proteins by peptide insertion has created the possibility of using adeno‐associated viral (AAV) vectors for receptor…”
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Conditional gene vectors regulated in cis by Pich, Dagmar, Humme, Sibille, Spindler, Mark-Peter, Schepers, Aloys, Hammerschmidt, Wolfgang

“…Non-integrating gene vectors, which are stably and extrachromosomally maintained in transduced cells would be perfect tools to support long-term expression of…”
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Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-Diseased Lung Cells Using a Dedicated Dataset by Belcastro, Vincenzo, Poussin, Carine, Gebel, Stephan, Mathis, Carole, Schlage, Walter K., Lichtner, Rosemarie B., Quadt-Humme, Sibille, Wagner, Sandra, Hoeng, Julia, Peitsch, Manuel C.

“…We recently constructed a computable cell proliferation network (CPN) model focused on lung tissue to unravel complex biological processes and their…”
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CD8 T cell recognition of endogenously expressed epstein-barr virus nuclear antigen 1 by Lee, Steven P, Brooks, Jill M, Al-Jarrah, Hatim, Thomas, Wendy A, Haigh, Tracey A, Taylor, Graham S, Humme, Sibille, Schepers, Aloys, Hammerschmidt, Wolfgang, Yates, John L, Rickinson, Alan B, Blake, Neil W

“…The Epstein-Barr virus (EBV) nuclear antigen (EBNA)1 contains a glycine-alanine repeat (GAr) domain that appears to protect the antigen from proteasomal…”
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Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus by Ritzi, Marion, Tillack, Kristina, Gerhardt, Jeannine, Ott, Elisabeth, Humme, Sibille, Kremmer, Elisabeth, Hammerschmidt, Wolfgang, Schepers, Aloys

“…The sequential binding of the origin recognition complex (ORC), Cdc6p and the minichromosome maintenance proteins (MCM2-7) mediates replication competence at…”
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IL-12-induced T-bet expression and IFN γ release in lymphocytes from asthmatics—Role of MAPkinases ERK-1/-2, p38MAPK and effect of dexamethasone by Koch, Andrea, Raidl, Maria, Lux, Michael, Müller, Katja, Büning, Hildegard, Humme, Sibille, Erdmann, Erland

“…Summary The transcription factor T-box-expressed-in-T-cells (T-bet) is required for TH 1 lymphocyte differentiation, regulates the IL-12-induced expression of…”
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IL-12-induced T-bet expression and IFNgamma release in lymphocytes from asthmatics--role of MAPkinases ERK-1/-2, p38(MAPK) and effect of dexamethasone by Koch, Andrea, Raidl, Maria, Lux, Michael, Müller, Katja, Büning, Hildegard, Humme, Sibille, Erdmann, Erland

“…The transcription factor T-box-expressed-in-T-cells (T-bet) is required for T(H)1 lymphocyte differentiation, regulates the IL-12-induced expression of the…”
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IL-12-induced T-bet expression and IFN [gamma] release in lymphocytes from asthmatics--Role of MAPkinases ERK-1/-2, p38 MAPK and effect of dexamethasone by Koch, Andrea, Raidl, Maria, Lux, Michael, Müller, Katja, Büning, Hildegard, Humme, Sibille, Erdmann, Erland

“…The transcription factor T-box-expressed-in-T-cells (T-bet) is required for TH1 lymphocyte differentiation, regulates the IL-12-induced expression of the…”
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IL-12-induced T-bet expression and IFN γ release in lymphocytes from asthmatics—Role of MAPkinases ERK-1/-2, p38 MAPK and effect of dexamethasone by Koch, Andrea, Raidl, Maria, Lux, Michael, Müller, Katja, Büning, Hildegard, Humme, Sibille, Erdmann, Erland

“…The transcription factor T-box-expressed-in-T-cells (T-bet) is required for T H1 lymphocyte differentiation, regulates the IL-12-induced expression of the T…”
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117. HSPG Binding Properties of Adeno- Associated Virus Retargeting Mutants and Consequences for Their In Vivo Tropism by Goldnau, Daniela, Perabo, Luca, White, Kathryn, Endell, Jan, Humme, Sibille, Work, Lorraine, Jannicki, Hanna, Hallek, Michael, Baker, Andrew H., Buening, Hildegard

“…Different technologies have been developed to control or redirect tropism of adeno-associated virus of type 2 (AAV-2) by genetic capsid modification. Many of…”
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Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-Diseased Lung Cells Using a Dedicated Dataset by Vincenzo Belcastro, Carine Poussin, Stephan Gebel, Carole Mathis, Walter K. Schlage, Rosemarie B. Lichtner, Sibille Quadt-Humme, Sandra Wagner, Julia Hoeng, Manuel C. Peitsch

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