Search Results - "HULETTE, C"

Microvascular injury and blood–brain barrier leakage in Alzheimer's disease by Zipser, B.D, Johanson, C.E, Gonzalez, L, Berzin, T.M, Tavares, R, Hulette, C.M, Vitek, M.P, Hovanesian, V, Stopa, E.G

“…Abstract Thinning and discontinuities within the vascular basement membrane (VBM) are associated with leakage of the plasma protein prothrombin across the…”
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Relationship of CD86 surface marker expression and cytotoxicity on dendritic cells exposed to chemical allergen by Hulette, Ben C., Ryan, Cindy A., Gildea, Lucy A., Gerberick, G. Frank

“…Human peripheral blood-derived dendritic cells (DC) respond to a variety of chemical allergens by up-regulating expression of the co-stimulatory molecule CD86…”
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Increased Amyloid β-Peptide Deposition in Cerebral Cortex as a Consequence of Apolipoprotein E Genotype in Late-Onset Alzheimer Disease by Schmechel, D. E., Saunders, A. M., Strittmatter, W. J., Crain, B. J., Hulette, C. M., Joo, S. H., Pericak-Vance, M. A., Goldgaber, D., Roses, A. D.

“…Amyloid β-peptide (Aβ) deposition in senile plaques and cerebral vessels is a neuropathological feature of Alzheimer disease (AD). We examined the possibility…”
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FDG PET Imaging in Patients with Pathologically Verified Dementia by Hoffman, John M, Welsh-Bohmer, Kathleen A, Hanson, Michael, Crain, Barbara, Hulette, Christine, Earl, Nancy, Coleman, R. Edward

“…The purpose of this study was to confirm with pathologic verification 2 beliefs related to Alzheimer's disease (AD): (a) the long-standing impression that…”
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Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A/8q21 by Vance, Jeffery M, Baxter, Rachel V, Ben Othmane, Kamel, Rochelle, Julie M, Stajich, Jason E, Hulette, Christine, Dew-Knight, Susan, Hentati, Faycal, Ben Hamida, Mongi, Bel, S, Stenger, Judy E, Gilbert, John R, Pericak-Vance, Margaret A

“…We previously localized and fine-mapped Charcot Marie Tooth 4A (CMT4A), the autosomal recessive, demyelinating peripheral neuropathy, to chromosome 8. Through…”
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Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen by Ryan, Cindy A., Gildea, Lucy A., Hulette, Ben C., Dearman, Rebecca J., Kimber, Ian, Gerberick, G.Frank

“…A critical step in the induction of allergic contact allergy is the activation and subsequent migration of Langerhans cells (LC), an important antigen…”
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Neuropathological and Neuropsychological Changes in “Normal” Aging: Evidence for Preclinical Alzheimer Disease in Cognitively Normal Individuals by HULETTE, CHRISTINE M, WELSH-BOHMER, KATHLEEN A, MURRAY, MICHAEL G, SAUNDERS, ANN M, MASH, DEBORAH C, MCINTYRE, LAUREN M

“…The presence of diffuse or primitive senile plaques in the neocortex of cognitively normal elderly at autopsy has been presumed to represent normal aging…”
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Twin pairs discordant for neuropathologically confirmed Lewy body dementia by Sheei-Meei Wang, C, Burke, J R, Steffens, D C, Hulette, C M, Breitner, J C S, Plassman, B L

“…Aim: Little is known about the concordance rate in twins for dementia with Lewy bodies (DLB). The rate of agreement between clinical and pathological diagnoses…”
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Intracranial volume and dementia: Some evidence in support of the cerebral reserve hypothesis by Tate, D.F, Neeley, E.S, Norton, M.C, Tschanz, J.T, Miller, M.J, Wolfson, L, Hulette, C, Leslie, C, Welsh-Bohmer, K.A, Plassman, B, Bigler, Erin D

“…Abstract The brain reserve hypothesis has been posited as being one important mediating factor for developing dementia, especially Alzheimer's disease (AD)…”
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Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease by SAUNDERS, A. M, STRITTMATTER, W. J, HULETTE, C, CRAIN, B, GOLDGABER, D, ROSES, A. D, SCHMECHEL, D, ST. GEORGE-HYSLOP, P. H, PERICAK-VANCE, M. A, JOO, S. H, ROSI, B. L, GUSELLA, J. F, CRAPPER-MACLACHLAN, D. R, ALBERTS, M. J

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Presenilin-1 mutations in Alzheimer's disease by Russo, C, Schettini, G, Saido, T C, Hulette, C, Lippa, C, Lannfelt, L, Ghetti, B, Gambetti, P, Tabaton, M, Teller, J K

“…Mutations in the gene encoding the protein presenilin-1 are the most common cause of familial Alzheimer's disease and they often produce a different disease…”
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Effect of APOE genotype on microvascular basement membrane in Alzheimer's disease by Salloway, S, Gur, T, Berzin, T, Zipser, B, Correia, S, Hovanesian, V, Fallon, J, Kuo-Leblanc, V, Glass, D, Hulette, C, Rosenberg, C, Vitek, M, Stopa, E

“…APOE4 homozygosity has been associated with an increased risk of sporadic Alzheimer's disease through a mechanism, which has yet to be defined. Recent evidence…”
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Fine Mapping of the Chromosome 12 Late-Onset Alzheimer Disease Locus: Potential Genetic and Phenotypic Heterogeneity by Scott, W.K., Grubber, J.M., Conneally, P.M., Small, G.W., Hulette, C.M., Rosenberg, C.K., Saunders, A.M., Roses, A.D., Haines, J.L., Pericak-Vance, M.A.

“…Apolipoprotein E (APOE) is the only confirmed susceptibility gene for late-onset Alzheimer disease (AD). In a recent genomic screen of 54 families with…”
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Elucidating Changes in Surface Marker Expression of Dendritic Cells Following Chemical Allergen Treatment by Hulette, Ben C., Ryan, Cindy A., Gerberick, G.Frank

“…Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) located in lymphoid and many nonlymphoid tissues, and Langerhans cells (LC), a…”
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Correlation of Hippocampal Neuronal Density and FDG‐PET in Mesial Temporal Lobe Epilepsy by Foldvary, N., Lee, N., Hanson, M. W., Coleman, R. E., Hulette, C. M., Friedman, A. H., Bej, M. D., Radtke, R. A.

“…Purpose: Interictal [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) reveals regional hypometabolism in 60–80% of patients with mesial temporal…”
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Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage by Hauser, Michael A., Li, Yi-Ju, Takeuchi, Satoshi, Walters, Robert, Noureddine, Maher, Maready, Melinda, Darden, Tiffany, Hulette, Christine, Martin, Eden, Hauser, Elizabeth, Xu, Hong, Schmechel, Don, Stenger, Judith E., Dietrich, Fred, Vance, Jeffery

“…We present a multifactorial, multistep approach called genomic convergence that combines gene expression with genomic linkage analysis to identify and…”
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Diagnosis of Intracranial Vasculitis: A Multi-disciplinary Approach by Chu, Charleen T, Gray, Linda, Larry, B, Goldstein, Hulette, Christine M

“…Intracranial vasculitis, or primary angiitis of the central nervous system (PACNS), is an uncommon, often fatal disorder that frequently responds to aggressive…”
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Use of a B Cell Marker (B220) to Discriminate between Allergens and Irritants in the Local Lymph Node Assay by Gerberick, G. Frank, Cruse, Lynn W., Ryan, Cindy A., Hulette, Ben C., Chaney, Joel G., Skinner, Robert A., Dearman, Rebecca J., Kimber, Ian

“…It has been shown that exposure of mice to contact allergens induces B cell activation in the draining lymph nodes (DLN), as seen by an increase in the…”
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Longitudinal follow-up of late-onset Alzheimer disease families by Carney, R.M., Slifer, M.A., Lin, P.I., Gaskell, P.C., Scott, W.K., Potocky, C.F., Hulette, C.M., Welsh-Bohmer, K.A., Schmechel, D.E., Vance, J.M., Pericak-Vance, M.A.

“…Historically, data for genetic studies are collected at one time point. However, for diseases with late onset or with complex phenotypes, such as Alzheimer…”
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Pattern of interleukin-6 receptor complex immunoreactivity between cortical regions of rapid autopsy normal and Alzheimer's disease brain by Hampel, Harald, Haslinger, Andreas, Scheloske, Michael, Padberg, Frank, Fischer, Petra, Unger, Josef, Teipel, Stefan Johannes, Neumann, Michaela, Rosenberg, Carlyn, Oshida, Rusti, Hulette, Christine, Pongratz, Dieter, Ewers, Michael, Kretzschmar, H A, Möller, Hans-Jürgen

“…Involvement of the interleukin-6 receptor complex (IL-6RC) in neuroregulatory and immunological processes of the brain and particularly in Alzheimer's disease…”
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