Search Results - "HUGUET, Francoise"

Discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia: Recommendations for clinical practice from the French Chronic Myeloid Leukemia Study Group by Rea, Delphine, Ame, Shanti, Berger, Marc, Cayuela, Jean‐Michel, Charbonnier, Aude, Coiteux, Valérie, Cony‐Makhoul, Pascale, Dubruille, Viviane, Dulucq, Stéphanie, Etienne, Gabriel, Legros, Laurence, Nicolini, Franck, Roche‐Lestienne, Catherine, Escoffre‐Barbe, Martine, Gardembas, Martine, Guerci‐Bresler, Agnès, Johnson‐Ansah, Hyacinthe, Rigal‐Huguet, Françoise, Rousselot, Philippe, Mahon, François‐Xavier

“…BACKGROUND The ultimate goal of chronic myeloid leukemia management in the tyrosine kinase inhibitor (TKI) era for patients who obtain deep molecular responses…”
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Efficacy and safety of nilotinib in chronic myeloid leukaemia patients who failed to achieve a treatment‐free remission period after imatinib discontinuation: Results of the French Nilo post‐STIM study by Dulucq, Stéphanie, Rigal‐Huguet, Françoise, Nicolini, Franck E., Cony‐Makhoul, Pascale, Escoffre‐Barbe, Martine, Gardembas, Martine, Legros, Laurence, Rousselot, Philippe, Liu, Jixing, Rea, Delphine, De Mas, Véronique, Hayette, Sandrine, Raynaud, Sophie, Lacoste‐Roussillon, Caroline, Robbesyn, Fanny, Klein, Emilie, Morisset, Stéphane, Mahon, François‐Xavier, Etienne, Gabriel

“…Summary Molecular recurrence (MRec) occurs in about half of all patients with chronic myeloid leukaemia (CML) who discontinue tyrosine kinase inhibitors (TKI)…”
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Pediatric-Inspired Therapy in Adults With Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia: The GRAALL-2003 Study by HUGUET, Francoise, LEGUAY, Thibaut, VERNANT, Jean-Paul, LAFAGE-POCHITALOFF, Marina, CHASSEVENT, Agnès, LHERITIER, Véronique, MACINTYRE, Elizabeth, BENE, Marie-Christine, IFRAH, Norbert, DOMBRET, Hervé, RAFFOUX, Emmanuel, THOMAS, Xavier, BELDJORD, Kheira, DELABESSE, Eric, CHEVALLIER, Patrice, BUZYN, Agnes, DELANNOY, André, CHALANDON, Yves

“…Retrospective comparisons have suggested that adolescents or teenagers with acute lymphoblastic leukemia (ALL) benefit from pediatric rather than adult…”
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The initial molecular response predicts the deep molecular response but not treatment-free remission maintenance in a real-world chronic myeloid leukemia cohort by Saugues, Sandrine, Lambert, Céline, Daguenet, Elisabeth, Roth-Guepin, Gabrielle, Huguet, Françoise, Cony-Makhoul, Pascale, Ansah, Hyacinthe Johnson, Escoffre-Barbe, Martine, Turhan, Ali, Rousselot, Philippe, Tchirkov, Andreï, Hamroun, Dalil, Hermet, Eric, Pereira, Bruno, Berger, Marc G

“…In chronic myeloid leukemia, the identification of early molecular predictors of stable treatment-free remission (TFR) after tyrosine kinase inhibitor (TKI)…”
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Long-term exposure and response to azacitidine for post-hematopoietic stem cell transplantation relapse of early T-cell precursor acute lymphoblastic leukemia: a case report and review of the literature by Jeanselme, Pauline, Tavitian, Suzanne, Lapierre, Léopoldine, Vergez, François, Rigolot, Lucie, Huynh, Anne, Bertoli, Sarah, Delabesse, Eric, Huguet, Françoise

“…Adult T-cell acute lymphoblastic leukemia has a poor outcome after relapse. Because the subtype of early T-cell precursor displays characteristics close of…”
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Evaluation of Residual Disease and TKI Duration Are Critical Predictive Factors for Molecular Recurrence after Stopping Imatinib First-line in Chronic Phase CML Patients by Nicolini, Franck Emmanuel, Dulucq, Stéphanie, Boureau, Lisa, Cony-Makhoul, Pascale, Charbonnier, Aude, Escoffre-Barbe, Martine, Rigal-Huguet, Françoise, Coiteux, Valérie, Varet, Bruno, Dubruille, Viviane, Lenain, Pascal, Rousselot, Philippe, Rea, Delphine, Guerci-Bresler, Agnès, Legros, Laurence, Liu, Jixing, Gardembas, Martine, Ianotto, Jean-Christophe, Turlure, Pascal, Johnson-Ansah, Hyacinthe, Martiniuc, Juliana, Jardel, Henry, Joly, Bertrand, Zunic, Patricia, Henni, Tawfiq, Villemagne, Bruno, Berger, Marc G, Cayssials, Emilie, Guilhot, François, Larosa, Fabrice, Guilhot, Joëlle, Etienne, Gabriel, Mahon, François-Xavier

“…Tyrosine kinase inhibitor (TKI) discontinuation is an emerging goal in chronic myelogenous leukemia (CML) management and several studies have demonstrated the…”
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Ribavirin for Chronic Hepatitis Prevention among Patients with Hematologic Malignancies by Tavitian, Suzanne, Peron, Jean-Marie, Huguet, Françoise, Kamar, Nassim, Abravanel, Florence, Beyne-Rauzy, Odile, Oberic, Lucie, Faguer, Stanislas, Alric, Laurent, Roussel, Murielle, Gaudin, Clément, Ysebaert, Loïc, Huynh, Anne, Recher, Christian

“…Findings among a cohort of 26 patients who had hematologic malignancies and hepatitis E virus (HEV) infection support that HEV can induce chronic hepatitis…”
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Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia by Touzart, Aurore, Boissel, Nicolas, Belhocine, Mohamed, Smith, Charlotte, Graux, Carlos, Latiri, Mehdi, Lhermitte, Ludovic, Mathieu, Eve-Lyne, Huguet, Françoise, Lamant, Laurence, Ferrier, Pierre, Ifrah, Norbert, Macintyre, Elizabeth, Dombret, Hervé, Asnafi, Vahid, Spicuglia, Salvatore

“…Cancer cells undergo massive alterations in their DNA methylation patterns which result in aberrant gene expression and malignant phenotypes. Abnormal DNA…”
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Phase III Randomized Study of Bendamustine Compared With Chlorambucil in Previously Untreated Patients With Chronic Lymphocytic Leukemia by KNAUF, Wolfgang U, LISSICHKOV, Toshko, BECKER, Martin, FRICKE, Hans-Joerg, HUGUET, Francoise, DEL GIUDICE, Ilaria, KLEIN, Peter, TREMMEL, Lothar, MERKLE, Karlheinz, MONTILLO, Marco, ALDAOUD, Ali, LIBERATI, Anna, LOSCERTALES, Javier, HERBRECHT, Raoul, JULIUSSON, Gunnar, POSTNER, Gerhard, GERCHEVA, Liana, GORANOV, Stefan

“…This randomized, open-label, parallel-group, multicenter study was designed to compare the efficacy and safety of bendamustine and chlorambucil in previously…”
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Significance of Measurable Residual Disease in Adult Philadelphia Chromosome-Positive ALL: A GRAAPH-2014 Study by Kim, Rathana, Chalandon, Yves, Rousselot, Philippe, Cayuela, Jean-Michel, Huguet, Françoise, Balsat, Marie, Passet, Marie, Chevallier, Patrice, Hicheri, Yosr, Raffoux, Emmanuel, Leguay, Thibaut, Chantepie, Sylvain, Maury, Sébastien, Hayette, Sandrine, Solly, Françoise, Braun, Thorsten, De Prijck, Bernard, Cacheux, Victoria, Salanoubat, Celia, Farnault, Laure, Guibaud, Isabelle, Lamarque, Mathilde, Gastaud, Lauris, Lemasle, Emilie, Brissot, Eolia, Tavernier, Emmanuelle, Bilger, Karine, Villate, Alban, Soulier, Jean, Graux, Carlos, Lhéritier, Véronique, Dombret, Hervé, Boissel, Nicolas, Clappier, Emmanuelle

“…quantification is widely regarded as the standard for monitoring measurable residual disease (MRD) in Philadelphia chromosome-positive (Ph+) ALL. However,…”
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Kinetics of early and late molecular recurrences after first-line imatinib cessation in chronic myeloid leukemia: updated results from the STIM2 trial by Dulucq, Stéphanie, Nicolini, Franck E, Rea, Delphine, Cony-Makhoul, Pascale, Charbonnier, Aude, Escoffre-Barbe, Martine, Coiteux, Valérie, Lenain, Pascal, Rigal-Huguet, Françoise, Liu, Jixing, Guerci-Bresler, Agnès, Legros, Laurence, Ianotto, Jean-Christophe, Gardembas, Martine, Turlure, Pascal, Dubruille, Viviane, Rousselot, Philippe, Martiniuc, Juliana, Jardel, Henry, Johnson-Ansah, Hyacinthe, Joly, Bertrand, Henni, Tawfiq, Cayssials, Emilie, Zunic, Patricia, Berger, Marc G, Villemagne, Bruno, Robbesyn, Fanny, Morisset, Stephane, Mahon, François-Xavier, Etienne, Gabriel

“…Discontinuation of tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia is feasible in clinical practice based on recently published…”
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Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome–positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study by de Labarthe, Adrienne, Rousselot, Philippe, Huguet-Rigal, Françoise, Delabesse, Eric, Witz, Francis, Maury, Sébastien, Réa, Delphine, Cayuela, Jean-Michel, Vekemans, Marie-Christine, Reman, Oumedaly, Buzyn, Agnès, Pigneux, Arnaud, Escoffre, Martine, Chalandon, Yves, MacIntyre, Elizabeth, Lhéritier, Véronique, Vernant, Jean-Paul, Thomas, Xavier, Ifrah, Norbert, Dombret, Hervé

“…The combination of imatinib with chemotherapy has been recently reported as very promising in patients with Philadelphia chromosome–positive (Ph+) acute…”
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Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis by Kim, Rathana, Bergugnat, Hugo, Larcher, Lise, Duchmann, Matthieu, Passet, Marie, Gachet, Stéphanie, Cuccuini, Wendy, Lafage-Pochitaloff, Marina, Pastoret, Cédric, Grardel, Nathalie, Asnafi, Vahid, Schäfer, Beat W, Delabesse, Eric, Itzykson, Raphaël, Adès, Lionel, Hicheri, Yosr, Chalandon, Yves, Graux, Carlos, Chevallier, Patrice, Hunault, Mathilde, Leguay, Thibaut, Huguet, Françoise, Lhéritier, Véronique, Dombret, Hervé, Soulier, Jean, Rousselot, Philippe, Boissel, Nicolas, Clappier, Emmanuelle

“…Low hypodiploidy defines a rare subtype of B-cell acute lymphoblastic leukemia (B-ALL) with a dismal outcome. To investigate the genomic basis of…”
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CD34 + CD38 - CD123 + Leukemic Stem Cell Frequency Predicts Outcome in Older Acute Myeloid Leukemia Patients Treated by Intensive Chemotherapy but Not Hypomethylating Agents by Vergez, François, Nicolau-Travers, Marie-Laure, Bertoli, Sarah, Rieu, Jean-Baptiste, Tavitian, Suzanne, Bories, Pierre, Luquet, Isabelle, Mas, Véronique De, Largeaud, Laetitia, Sarry, Audrey, Huguet, Françoise, Delabesse, Eric, Bérard, Emilie, Récher, Christian

“…The prognostic impact of immunophenotypic CD34 CD38 CD123 leukemic stem cell (iLSC) frequency at diagnosis has been demonstrated in younger patients treated by…”
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Therapy-related acute myeloid leukemia following treatment of lymphoid malignancies by Bertoli, Sarah, Sterin, Arthur, Tavitian, Suzanne, Oberic, Lucie, Ysebaert, Loïc, Bouabdallah, Reda, Vergez, François, Sarry, Audrey, Bérard, Emilie, Huguet, Françoise, Laurent, Guy, Prébet, Thomas, Vey, Norbert, Récher, Christian

“…Therapy-related acute myeloid leukemia (t-AML) is a heterogeneous entity most frequently related to breast cancer or lymphoproliferative diseases (LD)…”
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Treatment of newly diagnosed acute promyelocytic leukemia (APL): a comparison of French-Belgian-Swiss and PETHEMA results by Adès, Lionel, Sanz, Miguel A., Chevret, Sylvie, Montesinos, Pau, Chevallier, Patrice, Raffoux, Emmanuel, Vellenga, Edo, Guerci, Agnès, Pigneux, Arnaud, Huguet, Francoise, Rayon, Consuelo, Stoppa, Anne Marie, de la Serna, Javier, Cahn, Jean-Yves, Meyer-Monard, Sandrine, Pabst, Thomas, Thomas, Xavier, de Botton, Stéphane, Parody, Ricardo, Bergua, Juan, Lamy, Thierry, Vekhoff, Anne, Negri, Silvia, Ifrah, Norbert, Dombret, Hervé, Ferrant, Augustin, Bron, Dominique, Degos, Laurent, Fenaux, Pierre

“…All-trans retinoic acid (ATRA) plus anthracycline chemotherapy is the reference treatment of newly diagnosed acute promyelocytic leukemia (APL), whereas the…”
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Prophylaxis of invasive aspergillosis with voriconazole or caspofungin during building work in patients with acute leukemia by CHABROL, Amélie, CUZIN, Lise, RECHER, Christian, HUGUET, Françoise, ALVAREZ, Muriel, VERDEIL, Xavier, LINAS, Marie Denise, CASSAING, Sophie, GIRON, Jacques, TETU, Laurent, ATTAL, Michel

“…Invasive aspergillosis is a common life-threatening infection in patients with acute leukemia. The presence of building work near to hospital wards in which…”
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Vincristine, dexamethasone and epratuzumab for older relapsed/refractory CD22+ B-acute lymphoblastic leukemia patients: a phase II study by Chevallier, Patrice, Huguet, Francoise, Raffoux, Emmanuel, Etienne, Anne, Leguay, Thibaut, Isnard, Francoise, Robillard, Nelly, Guillaume, Thierry, Delaunay, Jacques, Charbonnier, Aude, Pigneux, Arnaud, Peterlin, Pierre, Bené, Marie C, Wegener, William A, Goldenberg, David M, Dombret, Hervé

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Outcome of treatment in adults with Philadelphia chromosome–positive acute lymphoblastic leukemia—results of the prospective multicenter LALA-94 trial by Dombret, Hervé, Gabert, Jean, Boiron, Jean-Michel, Rigal-Huguet, Françoise, Blaise, Didier, Thomas, Xavier, Delannoy, André, Buzyn, Agnès, Bilhou-Nabera, Chrystèle, Cayuela, Jean-Michel, Fenaux, Pierre, Bourhis, Jean-Henri, Fegueux, Nathalie, Charrin, Christiane, Boucheix, Claude, Lhéritier, Véronique, Espérou, Hélène, MacIntyre, Elizabeth, Vernant, Jean-Paul, Fière, Denis

“…From 1994 to 2000, 154 adults with Philadelphia chromosome–positive (Ph+) and/orBCR-ABL+acute lymphoblastic leukemia (ALL) were treated according to a…”
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Hyper-CVAD + epratuzumab as a salvage regimen for younger patients with relapsed/refractory CD22-positive precursor B-cell acute lymphocytic leukemia by Chevallier, Patrice, Chantepie, Sylvain, Huguet, Francoise, Raffoux, Emmanuel, Thomas, Xavier, Leguay, Thibaut, Marchand, Tony, Isnard, Francoise, Charbonnier, Aude, Maury, Sébastien, Gallego-Hernanz, Maria-Pilar, Robillard, Nelly, Guillaume, Thierry, Peterlin, Pierre, Garnier, Alice, Rialland, Fanny, Le Houerou, Claire, Goldenberg, David M, Wegener, William A, Béné, Marie-C, Dombret, Hervé

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