Search Results - "HUDSON, Sherry A"

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis by Kiwamoto, Takumi, MD, PhD, Katoh, Toshihiko, PhD, Evans, Christopher M., PhD, Janssen, William J., MD, Brummet, Mary E., MS, Hudson, Sherry A., MSB, Zhu, Zhou, MD, PhD, Tiemeyer, Michael, PhD, Bochner, Bruce S., MD

“…Background Sialic acid–binding, immunoglobulin-like lectin (Siglec) F is a glycan-binding protein selectively expressed on mouse eosinophils. Its engagement…”
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Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis by Nutku, Esra, Aizawa, Hideyuki, Hudson, Sherry A., Bochner, Bruce S.

“…Sialic acid binding immunoglobulin-like lectin 8 (Siglec-8), which exists in 2 isoforms including one possessing cytoplasmic tyrosine motifs, is expressed only…”
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Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen by Mao, Hui, Kano, Gen, Hudson, Sherry A, Brummet, Mary, Zimmermann, Nives, Zhu, Zhou, Bochner, Bruce S

“…Siglec-F and Siglec-8 are functional paralog proapoptotic cell surface receptors expressed on mouse and human eosinophils, respectively. Whereas Siglec-8…”
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Interleukin-5 Priming of Human Eosinophils Alters Siglec-8 Mediated Apoptosis Pathways by Nutku-Bilir, Esra, Hudson, Sherry A, Bochner, Bruce S

“…Previously, we have identified the sequential activation of reactive oxygen species (ROS), mitochondria, and caspase-3, -8, and -9, in Siglec-8-mediated…”
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E-selectin receptors on human leukocytes by Nimrichter, Leonardo, Burdick, Monica M., Aoki, Kazuhiro, Laroy, Wouter, Fierro, Mark A., Hudson, Sherry A., Von Seggern, Christopher E., Cotter, Robert J., Bochner, Bruce S., Tiemeyer, Michael, Konstantopoulos, Konstantinos, Schnaar, Ronald L.

“…Selectins on activated vascular endothelium mediate inflammation by binding to complementary carbohydrates on circulating neutrophils. The human neutrophil…”
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Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6'-sulfated sialyl Lewis x by Hudson, Sherry A, Bovin, Nicolai V, Schnaar, Ronald L, Crocker, Paul R, Bochner, Bruce S

“…The lectin Siglec-8 (sialic acid-binding, immunoglobulin-like lectin), which is selectively expressed on eosinophil surfaces and regulates eosinophil survival,…”
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Inhibition of FcϵRI-dependent mediator release and calcium flux from human mast cells by sialic acid–binding immunoglobulin-like lectin 8 engagement by Yokoi, Hidenori, MD, Choi, Oksoon H., PhD, Hubbard, Walter, PhD, Lee, Hyun-Sil, PhD, Canning, Brendan J., PhD, Lee, Hyun H., MD, Ryu, Seung-Duk, PhD, von Gunten, Stephan, MD, PhD, Bickel, Carol A., MS, Hudson, Sherry A., MSB, MacGlashan, Donald W., MD, PhD, Bochner, Bruce S., MD

“…Background Sialic acid–binding immunoglobulin-like lectins (Siglecs) are a family of glycan-binding inhibitory receptors, and among them, Siglec-8 is…”
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Mechanism of Siglec-8-induced human eosinophil apoptosis: Role of caspases and mitochondrial injury by Nutku, Esra, Hudson, Sherry A., Bochner, Bruce S.

“…Sialic acid binding immunoglobulin like lectin (Siglec)-8 crosslinking with specific antibodies causes human eosinophil apoptosis. Mechanisms by which Siglec-8…”
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IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils by Na, Ho Jeong, Hudson, Sherry A., Bochner, Bruce S.

“…► Siglec-8 engagement causes human eosinophil apoptosis. ► We determined whether IL-33 behaves like IL-5 in augmenting this apoptosis. ► IL-33 was somewhat…”
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Activation of Human Leukocytes Reduces Surface P-Selectin Glycoprotein Ligand-1 (PSGL-1, CD162) and Adhesion to P-Selectin In Vitro by Davenpeck, Kelly L, Brummet, Mary E, Hudson, Sherry A, Mayer, Ruth J, Bochner, Bruce S

“…P-selectin glycoprotein ligand-1 (PSGL-1), the primary ligand for P-selectin, is constitutively expressed on the surface of circulating leukocytes. The…”
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Developmental, Malignancy-Related, and Cross-Species Analysis of Eosinophil, Mast Cell, and Basophil Siglec-8 Expression by Hudson, Sherry A., Herrmann, Harald, Du, Jian, Cox, Paul, Haddad, El-Bdaoui, Butler, Barbara, Crocker, Paul R., Ackerman, Steven J., Valent, Peter, Bochner, Bruce S.

“…Objective The aim of this study is to determine when during hematopoiesis Siglec-8 gets expressed, whether it is expressed on hematologic malignancies, and if…”
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Eotaxin-2 Alters Eosinophil Integrin Function via Mitogen-Activated Protein Kinases by Tachimoto, Hiroshi, Kikuchi, Matsuo, Hudson, Sherry A, Bickel, Carol A, Hamilton, Robert G, Bochner, Bruce S

“…Adhesion molecules and chemokines contribute to selective eosinophil recruitment in allergic inflammation. In this study, we examined the effects of eotaxin-2,…”
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Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions by Bochner, Bruce S, Hudson, Shery A, Xiao, Hui Qing, Liu, Mark C

“…Segmental antigen bronchoprovocation has long been used as a model to study allergic pulmonary inflammatory responses. Among the characteristics of the…”
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Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma by GAO, Pei-Song, SHIMIZU, Kenichi, CRUZ, Alvaro A, NISHIMURA, Masaharu, SU, Song-Nan, HIZAWA, Nobuyuki, BEATY, Terry H, MATHIAS, Rasika A, ROTHENBERG, Marc E, BARNES, Kathleen C, BOCHNER, Bruce S, GRANT, Audrey V, RAFAELS, Nicholas, ZHOU, Lin-Fu, HUDSON, Sherry A, KONNO, Satoshi, ZIMMERMANN, Nives, ARAUJO, Maria I, PONTE, Eduardo V

“…Sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) promotes the apoptosis of eosinophils and inhibits FcvarepsilonRI-dependent mediator release from…”
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Stimulation of Human Endothelium with IL-3 Induces Selective Basophil Accumulation In Vitro by Lim, Lina H. K, Burdick, Monica M, Hudson, Sherry A, Mustafa, Fatimah Bte, Konstantopoulos, Konstantinos, Bochner, Bruce S

“…Basophils have been shown to accumulate in allergic airways and other extravascular sites. Mechanisms responsible for the selective recruitment of basophils…”
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CCR3-Active Chemokines Promote Rapid Detachment of Eosinophils from VCAM-1 In Vitro by Tachimoto, Hiroshi, Burdick, Monica M, Hudson, Sherry A, Kikuchi, Matsuo, Konstantopoulos, Konstantinos, Bochner, Bruce S

“…Selective eosinophil recruitment is the result of orchestrated events involving cell adhesion molecules, chemokines, and their receptors. The mechanisms by…”
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Acquisition and alteration of adhesion molecules during cultured human mast cell differentiation by Tachimoto, Hiroshi, Hudson, Sherry A., Bochner, Bruce S.

“…Background: Mature human mast cells express several types of adhesion molecules on their surface. Interactions between extracellular matrix (ECM) and adhesion…”
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Expression and function of P-selectin glycoprotein ligand 1 (CD162) on human basophils by Taylor, Marcia L., Brummet, Mary E., Hudson, Sherry A., Miura, Katsu, Bochner, Bruce S.

“…Background: The endothelial cell adhesion molecule P-selectin may contribute to selective leukocyte migration in allergic diseases by binding to its ligand,…”
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Mechanisms of Siglec-F-Induced Eosinophil Apoptosis: A Role for Caspases but Not for SHP-1, Src Kinases, NADPH Oxidase or Reactive Oxygen. e68143 by Mao, Hui, Kano, Gen, Hudson, Sherry A, Brummet, Mary, Zimmermann, Nives, Zhu, Zhou, Bochner, Bruce S

“…Background Siglec-F and Siglec-8 are functional paralog proapoptotic cell surface receptors expressed on mouse and human eosinophils, respectively. Whereas…”
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Mechanisms of allergy and clinical immunology: Inhibition of Fc epsilon RI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement by Yokoi, Hidenori, Choi, Oksoon H, Hubbard, Walter, Lee, Hyun-Sil, Canning, Brendan J, Lee, Hyun H, Ryu, Seung-Duk, von Gunten, Stephan, Bickel, Carol A, Hudson, Sherry A, MacGlashan Jr, Donald W, Bochner, Bruce S

“…Background: Sialic acidbinding immunoglobulin-like lectins (Siglecs) are a family of glycan-binding inhibitory receptors, and among them, Siglec-8 is…”
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