Search Results - "HUANTE, Matthew B"

Inhibition of caspase pathways limits CD4 + T cell loss and restores host anti-retroviral function in HIV-1 infected humanized mice with augmented lymphoid tissue by Holloway, Alex J, Saito, Tais B, Naqvi, Kubra F, Huante, Matthew B, Fan, Xiuzhen, Lisinicchia, Joshua G, Gelman, Benjamin B, Endsley, Janice J, Endsley, Mark A

“…The study of HIV infection and pathogenicity in physical reservoirs requires a biologically relevant model. The human immune system (HIS) mouse is an…”
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A humanized mouse model of tuberculosis by Calderon, Veronica E, Valbuena, Gustavo, Goez, Yenny, Judy, Barbara M, Huante, Matthew B, Sutjita, Putri, Johnston, R Katie, Estes, D Mark, Hunter, Robert L, Actor, Jeffrey K, Cirillo, Jeffrey D, Endsley, Janice J

“…Mycobacterium tuberculosis (M.tb) is the second leading infectious cause of death worldwide and the primary cause of death in people living with HIV/AIDS…”
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Advancing our understanding of HIV co-infections and neurological disease using the humanized mouse by Endsley, Janice J, Huante, Matthew B, Naqvi, Kubra F, Gelman, Benjamin B, Endsley, Mark A

“…Humanized mice have become an important workhorse model for HIV research. Advances that enabled development of a human immune system in immune deficient mouse…”
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Therapeutic modulation of arginase with nor-NOHA alters immune responses in experimental mouse models of pulmonary tuberculosis including in the setting of Human Immunodeficiency Virus (HIV) co-infection by Chauhan, Sadhana, Nusbaum, Rebecca J, Huante, Matthew B, Holloway, Alex J, Endsley, Mark A, Gelman, Benjamin B, Lisinicchia, Joshua G, Endsley, Janice J

“…L-arginine metabolism is strongly linked with immunity to mycobacteria, primarily through the antimicrobial activity of nitric oxide (NO). The potential to…”
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Helper T cell bias following tuberculosis chemotherapy identifies opportunities for therapeutic vaccination to prevent relapse by Martinez-Martinez, Yazmin B., Huante, Matthew B., Chauhan, Sadhana, Naqvi, Kubra F., Bharaj, Preeti, Endsley, Janice J.

“…Therapeutic vaccines have promise as adjunctive treatment for tuberculosis (TB) or as preventives against TB relapse. An important development challenge is the…”
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Small Animal Model of Post-chemotherapy Tuberculosis Relapse in the Setting of HIV Co-infection by Huante, Matthew B, Saito, Tais B, Nusbaum, Rebecca J, Naqvi, Kubra F, Chauhan, Sadhana, Hunter, Robert L, Actor, Jeffrey K, Rudra, Jai S, Endsley, Mark A, Lisinicchia, Joshua G, Gelman, Benjamin B, Endsley, Janice J

“…Tuberculosis relapse following drug treatment of active disease is an important global public health problem due to the poorer clinical outcomes and increased…”
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Characterization of an F1 Deletion Mutant of Yersinia pestis CO92, Pathogenic Role of F1 Antigen in Bubonic and Pneumonic Plague, and Evaluation of Sensitivity and Specificity of F1 Antigen Capture-Based Dipsticks by JIAN SHA, ENDSLEY, Janice J, MOTIN, Vladimir L, PETERSON, Johnny W, DEBORD, Kristin L, CHOPRA, Ashok K, KIRTLEY, Michelle L, FOLTZ, Sheri M, HUANTE, Matthew B, EROVA, Tatiana E, KOZLOVA, Elena V, POPOV, Vsevolod L, YEAGER, Linsey A, ZUDINA, Irina V

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N-Glycans on the Rift Valley Fever Virus Envelope Glycoproteins Gn and Gc Redundantly Support Viral Infection via DC-SIGN by Phoenix, Inaia, Nishiyama, Shoko, Lokugamage, Nandadeva, Hill, Terence E, Huante, Matthew B, Slack, Olga A L, Carpio, Victor H, Freiberg, Alexander N, Ikegami, Tetsuro

“…Rift Valley fever is a mosquito-transmitted, zoonotic disease that infects humans and ruminants. Dendritic cell specific intercellular adhesion molecule 3…”
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Antibacterial Role for Natural Killer Cells in Host Defense to Bacillus anthracis by Gonzales, Christine M, Williams, Courtney B, Calderon, Veronica E, Huante, Matthew B, Moen, Scott T, Popov, Vsevolod L, Baze, Wallace B, Peterson, Johnny W, Endsley, Janice J

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Discovery and Mechanism of SARS-CoV‑2 Main Protease Inhibitors by Huff, Sarah, Kummetha, Indrasena Reddy, Tiwari, Shashi Kant, Huante, Matthew B, Clark, Alex E, Wang, Shaobo, Bray, William, Smith, Davey, Carlin, Aaron F, Endsley, Mark, Rana, Tariq M

“…The emergence of a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents an urgent public health crisis. Without available…”
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Novel Role for Macrophage Galactose-Type Lectin-1 to Regulate Innate Immunity against Mycobacterium tuberculosis by Naqvi, Kubra F, Huante, Matthew B, Saito, Tais B, Endsley, Mark A, Gelman, Benjamin B, Endsley, Janice J

“…Tuberculosis (TB) caused by infection with is characterized by inflammatory pathology and poorly understood mechanisms of innate immunity. Pattern recognition…”
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Pulmonary Tuberculosis in Humanized Mice Infected with HIV-1 by Nusbaum, Rebecca J., Calderon, Veronica E., Huante, Matthew B., Sutjita, Putri, Vijayakumar, Sudhamathi, Lancaster, Katrina L., Hunter, Robert L., Actor, Jeffrey K., Cirillo, Jeffrey D., Aronson, Judith, Gelman, Benjamin B., Lisinicchia, Joshua G., Valbuena, Gustavo, Endsley, Janice J.

“…Co-infection with HIV increases the morbidity and mortality associated with tuberculosis due to multiple factors including a poorly understood microbial…”
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Contribution of Human Lung Parenchyma and Leukocyte Influx to Oxidative Stress and Immune System-Mediated Pathology following Nipah Virus Infection by Escaffre, Olivier, Saito, Tais B, Juelich, Terry L, Ikegami, Tetsuro, Smith, Jennifer K, Perez, David D, Atkins, Colm, Levine, Corri B, Huante, Matthew B, Nusbaum, Rebecca J, Endsley, Janice J, Freiberg, Alexander N, Rockx, Barry

“…Nipah virus (NiV) is a zoonotic emerging paramyxovirus that can cause fatal respiratory illness or encephalitis in humans. Despite many efforts, the molecular…”
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Mycobacterium tuberculosis-specific CD8+ T cell recall in convalescing TB subjects with HIV co-infection by Ongaya, Asiko, Huante, Matthew B, Mwangi, Paul, Keiser, Philip H, Amukoye, Evans, Endsley, Janice J

“…Memory T cell populations recover following phase I chemotherapy for tuberculosis (TB) and augment the effectiveness of antibiotics during the continuation…”
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Further characterization of a highly attenuated Yersinia pestis CO92 mutant deleted for the genes encoding Braun lipoprotein and plasminogen activator protease in murine alveolar and primary human macrophages by van Lier, Christina J., Tiner, Bethany L., Chauhan, Sadhana, Motin, Vladimir L., Fitts, Eric C., Huante, Matthew B., Endsley, Janice J., Ponnusamy, Duraisamy, Sha, Jian, Chopra, Ashok K.

“…We recently characterized the Δlpp Δpla double in-frame deletion mutant of Yersinia pestis CO92 molecularly, biologically, and immunologically. While Braun…”
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Protective Role of IL-17 in Pulmonary Tuberculosis Relapse by Clark, Lucinda Puebla, Martinez-Martinez, Yazmin Berenice, Huante, Matthew B, Chauhan, Sadhana, Files, Megan A, Endsley, Janice J

“…Tuberculosis (TB) recurrence following drug treatment and apparent clinical cure affects an estimated 700,000 people annually and is increasingly associated…”
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C-type lectin receptor dysregulation in HIV and Mycobacterium tuberculosis co-infection by Browning, Sarah, Paez, Reina, Endsley, Mark A, Naqvi, Kubra, Huante, Matthew B, Chauhan, Sadhana, Gelman, Benjamin, Endsley, Janice J

“…Infection with Mycobacterium tuberculosis (Mtb) is a serious and potentially life-threatening condition, especially in people with HIV (PWH). According to the…”
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HIV compromises Th17 and Th22 immunity in a humanized mouse model of Tuberculosis and HIV co-infection by Martinez-Martinez, Yazmin Berenice, Huante, Matthew B, Files, Megan, Gelman, Benjamin B., Endsley, Mark, Endsley, Janice J

“…Tuberculosis (TB) kills an estimated 1–2 million people per year and is the leading cause of death in people with HIV (PWH). The CD4+ T helper (Th) populations…”
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Macrophage plasticity and activation states drive differential expression of murine macrophage galactose-type lectin (MGL) orthologs by Paez, Reina N, Browning, Sarah, Files, Megan A, Varghese, Alyssa A, Huante, Matthew B, Strong, Emily, Lee, Sunhee, Endsley, Mark A, Endsley, Janice J

“…Macrophage plasticity and functional activation are critical to the broad array of macrophage-mediated functions that help determine disease outcomes…”
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Novel Anti-bacterial and Anti-inflammatory Roles for the Macrophage Galactose-type Lectin in Pulmonary Immunity to Mycobacterium tuberculosis by Naqvi, Kubra Fatima, Huante, Matthew B, Endsley, Mark, Gelman, Benjamin, Endsley, Janice J

“…Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is characterized by inflammatory pathology that is regulated by poorly understood…”
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