Search Results - "HUANG, Yi Elaine"
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1
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis
Published in Developmental cell (01-04-2007)“…Directed cell migration involves signaling events that lead to local accumulation of PI(3,4,5)P(3), but additional pathways act in parallel. A genetic screen…”
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Journal Article -
2
Novel Mechanism of PTEN Regulation by Its Phosphatidylinositol 4,5-Bisphosphate Binding Motif Is Critical for Chemotaxis
Published in The Journal of biological chemistry (16-04-2004)“…In chemotaxing cells, localization of phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) to the leading edge of the cell sets the direction and regulates…”
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Journal Article -
3
Inositol Pyrophosphates Mediate Chemotaxis in Dictyostelium via Pleckstrin Homology Domain-PtdIns(3,4,5)P3 Interactions
Published in Cell (05-09-2003)“…Inositol phosphates are well-known signaling molecules, whereas the inositol pyrophosphates, such as diphosphoinositol pentakisphosphate (InsP7/IP7) and…”
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Journal Article -
4
Revealing the millipede and other soil-macrofaunal biodiversity in Hong Kong using a citizen science approach
Published in Biodiversity data journal (04-10-2022)“…Soil biodiversity plays important roles in nutrient recycling in both the environment and agriculture. However, they are generally understudied worldwide. To…”
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Journal Article -
5
Temporal and Spatial Regulation of Chemotaxis
Published in Developmental Cell (01-10-2002)“…The ability to sense and respond to shallow gradients of extracellular signals is remarkably similar in Dictyostelium discoideum amoebae and mammalian…”
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Book Review Journal Article -
6
Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis
Published in Molecular biology of the cell (01-12-2003)“…The directional movement of cells in chemoattractant gradients requires sophisticated control of the actin cytoskeleton. Uniform exposure of Dictyostelium…”
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Journal Article -
7
Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells
Published in Molecular biology of the cell (01-05-2003)“…Recent studies have demonstrated that PH domains specific for PI(3,4,5)P3 accumulate at the leading edge of a number of migrating cells and that PI3Ks and PTEN…”
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Journal Article -
8
Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase
Published in Molecular biology of the cell (01-04-2006)“…The role of PI(3,4,5)P(3) in Dictyostelium signal transduction and chemotaxis was investigated using the PI3-kinase inhibitor LY294002 and pi3k-null cells. The…”
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Journal Article -
9
Two Phases of Actin Polymerization Display Different Dependencies on PI(3,4,5)P 3 Accumulation and Have Unique Roles during Chemotaxis
Published in Molecular biology of the cell (01-12-2003)“…The directional movement of cells in chemoattractant gradients requires sophisticated control of the actin cytoskeleton. Uniform exposure of Dictyostelium…”
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Journal Article -
10
Receptor-mediated Regulation of PI3Ks Confines PI(3,4,5)P 3 to the Leading Edge of Chemotaxing Cells
Published in Molecular biology of the cell (01-05-2003)“…Recent studies have demonstrated that PH domains specific for PI(3,4,5)P 3 accumulate at the leading edge of a number of migrating cells and that PI3Ks and…”
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Journal Article -
11
Distinct Roles of PI(3,4,5)P 3 during Chemoattractant Signaling in Dictyostelium : A Quantitative In Vivo Analysis by Inhibition of PI3-Kinase
Published in Molecular biology of the cell (01-04-2006)“…The role of PI(3,4,5)P 3 in Dictyostelium signal transduction and chemotaxis was investigated using the PI3-kinase inhibitor LY294002 and pi3k-null cells. The…”
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Journal Article -
12
PLA 2 and PI3K/PTEN Pathways Act in Parallel to Mediate Chemotaxis
Published in Developmental cell (2007)“…Directed cell migration involves signaling events that lead to local accumulation of PI(3,4,5)P 3, but additional pathways act in parallel. A genetic screen in…”
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Journal Article -
13
Distinct Roles of PI(3,4,5)P3 during Chemoattractant Signaling in Dictyostelium: A Quantitative In Vivo Analysis by Inhibition of PI3-KinaseV
Published in Molecular biology of the cell (01-04-2006)“…The role of PI(3,4,5)P 3 in Dictyostelium signal transduction and chemotaxis was investigated using the PI3-kinase inhibitor LY294002 and pi3k -null cells. The…”
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Journal Article -
14
Distinct Roles of PI(3,4,5)P sub(3) during Chemoattractant Signaling in Dictyostelium: A Quantitative In Vivo Analysis by Inhibition of PI3-Kinase
Published in Molecular biology of the cell (01-04-2006)“…The role of PI(3,4,5)P sub(3) in Dictyostelium signal transduction and chemotaxis was investigated using the PI3-kinase inhibitor LY294002 and pi3k- null…”
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Journal Article -
15
Receptor-mediated Regulation of PI3Ks Confines PI(3,4,5)P sub(3) to the Leading Edge of Chemotaxing Cells
Published in Molecular biology of the cell (01-05-2003)“…Recent studies have demonstrated that PH domains specific for PI(3,4,5)P sub(3) accumulate at the leading edge of a number of migrating cells and that PI3Ks…”
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Journal Article -
16
Phosphatidylinositol signaling in chemotaxis
Published 01-01-2004“…Chemotaxis plays a very important role in many aspects of development, immunity, and tissue maintenance. In both Dictyostelium discoideum amoeba and mammalian…”
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Dissertation