Search Results - "HUANG, Haojie"

Interplay Among PI3K/AKT, PTEN/FOXO and AR Signaling in Prostate Cancer by Yan, Yuqian, Huang, Haojie

“…The PI3K signaling pathway is activated in a majority of cancer types. It promotes tumorigenesis by regulating nutrient metabolism, cell proliferation,…”
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Modulation of heat flux and thermal stress at the double interface by nano-coating thickness by Huang, Haojie, Song, Kun

“…Nano-coatings hold the key to unlocking the vital potential of three-phase nanocomposites by urgently addressing thermal stress concentration. Consequently,…”
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Dynamic FoxO transcription factors by Huang, Haojie, Tindall, Donald J

“…Forkhead box O (FoxO) transcription factors FoxO1, FoxO3a, FoxO4 and FoxO6, the mammalian orthologs of Caenorhabditis elegans DAF-16, are emerging as an…”
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Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma by Sun, Guangxi, Chen, Junru, Liang, Jiayu, Yin, Xiaoxue, Zhang, Mengni, Yao, Jin, He, Ning, Armstrong, Cameron M., Zheng, Linmao, Zhang, Xingming, Zhu, Sha, Sun, Xiaomeng, Yang, Xiaoxia, Zhao, Wanbin, Liao, Banghua, Pan, Xiuyi, Nie, Ling, Yang, Ling, Chen, Yuntian, Zhao, Jinge, Zhang, Haoran, Dai, Jindong, Shen, Yali, Liu, Jiyan, Huang, Rui, Liu, Jiandong, Wang, Zhipeng, Ni, Yuchao, Wei, Qiang, Li, Xiang, Zhou, Qiao, Huang, Haojie, Liu, Zhenhua, Shen, Pengfei, Chen, Ni, Zeng, Hao

“…TFE3 -translocation renal cell carcinoma ( TFE3 -tRCC) is a rare and heterogeneous subtype of kidney cancer with no standard treatment for advanced disease. We…”
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Comparison of the Indicators of Psychological Stress in the Population of Hubei Province and Non-Endemic Provinces in China During Two Weeks During the Coronavirus Disease 2019 (COVID-19) Outbreak in February 2020 by Yuan, Shuai, Liao, Zhenxin, Huang, Haojie, Jiang, Boyue, Zhang, Xueyan, Wang, Yingwen, Zhao, Mingyi

“…BACKGROUND During February 2020, the coronavirus disease 2019 (COVID-19) epidemic in Hubei Province, China, was at its height, requiring isolation of the…”
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Leveraging symmetries in pick and place by Huang, Haojie, Wang, Dian, Tangri, Arsh, Walters, Robin, Platt, Robert

“…Robotic pick and place tasks are symmetric under translations and rotations of both the object to be picked and the desired place pose. For example, if the…”
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CrossMap: a versatile tool for coordinate conversion between genome assemblies by Zhao, Hao, Sun, Zhifu, Wang, Jing, Huang, Haojie, Kocher, Jean-Pierre, Wang, Liguo

“…Reference genome assemblies are subject to change and refinement from time to time. Generally, researchers need to convert the results that have been analyzed…”
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Destruction of Full-Length Androgen Receptor by Wild-Type SPOP, but Not Prostate-Cancer-Associated Mutants by An, Jian, Wang, Chenji, Deng, Yibin, Yu, Long, Huang, Haojie

“…The SPOP E3 ubiquitin ligase gene is frequently mutated in human prostate cancers. Here, we demonstrate that SPOP recognizes a Ser/Thr-rich degron in the hinge…”
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Regulation of FOXO protein stability via ubiquitination and proteasome degradation by Huang, Haojie, Tindall, Donald J.

“…Forkhead box O-class (FOXO) proteins are evolutionally conserved transcription factors. They belong to a family of proteins consisting of FOXO1, FOXO3a, FOXO4…”
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DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4 by Jin, Xin, Yan, Yuqian, Wang, Dejie, Ding, Donglin, Ma, Tao, Ye, Zhenqing, Jimenez, Rafael, Wang, Liguo, Wu, Heshui, Huang, Haojie

“…The bromodomain and extra-terminal domain (BET) protein BRD4 is emerging as a promising anticancer therapeutic target. However, resistance to BET inhibitors…”
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CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers by Waddell, Aaron R, Huang, Haojie, Liao, Daiqing

“…The CREB-binding protein (CBP) and p300 are two paralogous lysine acetyltransferases (KATs) that were discovered in the 1980s-1990s. Since their discovery,…”
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Coinfection With HIV and SARS-CoV-2 in Wuhan, China: A 12-Person Case Series by Hu, Yifei, Ma, Juntao, Huang, Haojie, Vermund, Sten H.

“…BACKGROUND:Given the magnitude of the global COVID-19 pandemic, persons living with HIV (PLWH) may become coinfected with SARS-CoV-2. SETTING:We conducted a…”
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A noncanonical AR addiction drives enzalutamide resistance in prostate cancer by He, Yundong, Wei, Ting, Ye, Zhenqing, Orme, Jacob J., Lin, Dong, Sheng, Haoyue, Fazli, Ladan, Jeffrey Karnes, R., Jimenez, Rafael, Wang, Liguo, Wang, Liewei, Gleave, Martin E., Wang, Yuzhuo, Shi, Lei, Huang, Haojie

“…Resistance to next-generation anti-androgen enzalutamide (ENZ) constitutes a major challenge for the treatment of castration-resistant prostate cancer (CRPC)…”
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Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer by Wen, Simeng, He, Yundong, Wang, Liewei, Zhang, Jun, Quan, Changyi, Niu, Yuanjie, Huang, Haojie

“…Next generation antiandrogens such as enzalutamide (Enz) are effective initially for the treatment of castration-resistant prostate cancer (CRPC). However, the…”
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A theoretical model for structure inclination angles in stratified boundary layers: Connecting turbulent scaling and Monin–Obukhov similarity theory by Huang, Haojie, Li, Xuebo

“…Although scaling laws and coherent structures have been well-studied in non-neutral boundary layer flows over a long period of time, a potential connection…”
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Detection of Micro-Defects on Irregular Reflective Surfaces Based on Improved Faster R-CNN by Zhou, Zhuangzhuang, Lu, Qinghua, Wang, Zhifeng, Huang, Haojie

“…The detection of defects on irregular surfaces with specular reflection characteristics is an important part of the production process of sanitary equipment…”
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Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation by Zhang, Pingzhao, Wang, Dejie, Zhao, Yu, Ren, Shancheng, Gao, Kun, Ye, Zhenqing, Wang, Shangqian, Pan, Chun-Wu, Zhu, Yasheng, Yan, Yuqian, Yang, Yinhui, Wu, Di, He, Yundong, Zhang, Jun, Lu, Daru, Liu, Xiuping, Yu, Long, Zhao, Shimin, Li, Yao, Lin, Dong, Wang, Yuzhuo, Wang, Liguo, Chen, Yu, Sun, Yinghao, Wang, Chenji, Huang, Haojie

“…Mutations in SPOP , the gene encoding a component of the E3 ubiquitin ligase complex, impair ubiquitination-dependent degradation of BRD2, BRD3 and BRD4…”
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Aerodynamic performance of small wind turbines in sand-laden atmospheric flows by Wang, Yan, Zhang, Jingjing, Chai, Yongfen, Huang, Haojie, Liu, Hongyou

“…Within the context of global energy transitions, many wind turbines have been installed in desert and Gobi regions. Nevertheless, the impact of turbulence…”
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Characteristics of mesoscale eddies in the Mozambique Channel by Bai, Linfei, Zhu, Guohao, Huang, Haojie, Zhang, Liqiong, Lü, Haibin, Zhang, Yinyi

“…The mesoscale eddy characteristics of the Mozambique Warm Current were investigated by detecting and tracking satellite altimetry data from 2010 to 2019. A…”
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Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction by Jin, Xin, Pan, Yunqian, Wang, Liguo, Ma, Tao, Zhang, Lizhi, Tang, Amy H, Billadeau, Daniel D, Wu, Heshui, Huang, Haojie

“…Dysregulation of the MAPK pathway correlates with progression of pancreatic ductal adenocarcinoma (PDAC) progression. IQ motif containing GTPase-activating…”
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