Search Results - "HUAFENG WEI"

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    Ryanodine Receptors: A Potential Treatment Target in Various Neurodegenerative Disease by Sun, Liang, Wei, Huafeng

    Published in Cellular and molecular neurobiology (01-11-2021)
    “…Progressive neuronal demise is a key contributor to the key pathogenic event implicated in many different neurodegenerative disorders (NDDs). There are several…”
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    The Cytoprotective Effects of Dantrolene: A Ryanodine Receptor Antagonist by Inan, Saadet, Wei, Huafeng

    Published in Anesthesia and analgesia (01-12-2010)
    “…Calcium, as a second messenger, has an important role in a variety of cellular functions. However, disruption of intracellular calcium homeostasis leads to…”
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    Anesthetic neurotoxicity: Apoptosis and autophagic cell death mediated by calcium dysregulation by Yang, Meirong, MD, PhD, Wei, Huafeng, MD, PhD

    Published in Neurotoxicology and teratology (01-03-2017)
    “…Abstract A number of findings suggested that general anesthetics induced neural cell death by apoptosis in various animal models. Although clinical evidence…”
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    Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma by Zhang, Bin, Wang, Zhijun, Wu, Liangliang, Zhang, Meng, Li, Wei, Ding, Jianhua, Zhu, Jun, Wei, Huafeng, Zhao, Ke

    Published in PloS one (20-02-2013)
    “…Myeloid-derived suppressor cells (MDSCs) are a heterogeneous family of myeloid cells that suppress T cell immunity in tumor-bearing hosts. In patients with…”
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    Isoflurane Causes Greater Neurodegeneration Than an Equivalent Exposure of Sevoflurane in the Developing Brain of Neonatal Mice by GE LIANG, WARD, Christopher, JUN PENG, YIFAN ZHAO, BAOSHENG HUANG, HUAFENG WEI

    Published in Anesthesiology (Philadelphia) (01-06-2010)
    “…We hypothesized that isoflurane has a greater potency to induce neurodegeneration than sevoflurane in the developing brains of neonatal mice based on our…”
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    Dual effects of neuroprotection and neurotoxicity by general anesthetics: Role of intracellular calcium homeostasis by Wei, Huafeng, Inan, Saadet

    “…Although general anesthetics have long been considered neuroprotective, there are growing concerns about neurotoxicity. Preclinical studies clearly…”
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    Dantrolene : From Malignant Hyperthermia to Alzheimer's Disease by Shi, Yun, Wang, Yong, Wei, Huafeng

    Published in CNS & neurological disorders drug targets (01-01-2019)
    “…Dantrolene, a ryanodine receptor antagonist, is primarily known as the only clinically acceptable and effective treatment for Malignant Hyperthermia (MH)…”
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    Risk factors for pharyngalgia and xerostomia undergoing supraglottic jet oxygenation and ventilation in gastrointestinal endoscopy: a retrospective study by Xie, Ping, Wu, Zhiyun, Zha, Benjun, Xu, Li, Shen, Shanyi, Zhuang, Haibin, Wei, Huafeng

    Published in Scientific reports (11-12-2023)
    “…Supraglottic jet oxygenation/ventilation (SJOV) can reduce hypoxemia in sedated endoscopy but may increase minor side effects like pharyngalgia and xerostomia…”
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    Ascites-derived IL-6 and IL-10 synergistically expand CD14 + HLA-DR -/low myeloid-derived suppressor cells in ovarian cancer patients by Wu, Liangliang, Deng, Zhaoyang, Peng, Yaojun, Han, Lu, Liu, Jing, Wang, Linxiong, Li, Bohua, Zhao, Jian, Jiao, Shunchang, Wei, Huafeng

    Published in Oncotarget (29-09-2017)
    “…Myeloid-derived suppressor cells (MDSC) play a key immunosuppressive role in various types of cancer, including ovarian cancer (OC). In this study, we…”
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    Anesthesia, calcium homeostasis and Alzheimer's disease by Wei, Huafeng, Xie, Zhongcong

    Published in Current Alzheimer research (01-02-2009)
    “…While anesthetics are indispensable clinical tools generally safe and effective, in some situations there is grown concern about selective neurotoxicity of…”
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    Lung isolation—a personalized and clinically adapted approach to control bronchoscopy-associated acute massive airway hemorrhage by Yang, Mingyuan, Zhou, Yunzhi, Li, Hong, Wei, Huafeng, Cheng, Qinghao

    Published in BMC pulmonary medicine (30-11-2023)
    “…Abstract Background The current concept of bronchoscopy-associated massive airway hemorrhage is not accurate enough, and the amount of bleeding as the only…”
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    Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane by Yang, Bin, Liang, Ge, Khojasteh, Soorena, Wu, Zhen, Yang, Wenqiong, Joseph, Donald, Wei, Huafeng

    Published in PloS one (16-06-2014)
    “…While previous studies have demonstrated neuronal apoptosis and associated cognitive impairment after isoflurane or propofol exposure in neonatal rodents, the…”
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    Intranasal administration of dantrolene increased brain concentration and duration by Wang, Jintao, Shi, Yun, Yu, Shuchun, Wang, Yan, Meng, Qingcheng, Liang, Ge, Eckenhoff, Maryellen F, Wei, Huafeng

    Published in PloS one (11-03-2020)
    “…Dantrolene has been demonstrated to be neuroprotective for multiple neurodegenerative diseases. However, dantrolene's limited penetration into the CNS hampers…”
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    Osteopontin induces autophagy to promote chemo-resistance in human hepatocellular carcinoma cells by Liu, Guoke, Fan, Xiaoyu, Tang, Min, Chen, Rui, Wang, Hao, Jia, Rongjie, Zhou, Xuyu, Jing, Wei, Wang, Huajing, Yang, Yang, Yin, Fan, Wei, Huafeng, Li, Bohua, Zhao, Jian

    Published in Cancer letters (28-12-2016)
    “…Abstract Hepatocellular carcinoma (HCC) is a major health burden worldwide for its high incidence and mortality. Osteopontin (OPN) is a chemokine-like,…”
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    Approaches to Optimizing Dantrolene Neuroprotection for the Treatment of Alzheimer's Disease by Abou, Matan B, Sun, Liang, Wei, Huafeng

    Published in Current Alzheimer research (01-01-2020)
    “…Alzheimer's Disease (AD), a neurodegenerative disorder with high incidence and mortality, is leading its way to the top of the list of the deadliest diseases…”
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    PTK7-Targeting CAR T-Cells for the Treatment of Lung Cancer and Other Malignancies by Jie, Yamin, Liu, Guijun, Feng, Lina, Li, Ying, E, Mingyan, Wu, Liangliang, Li, Yinyin, Rong, Guanghua, Li, Yongwu, Wei, Huafeng, Gu, Anxin

    Published in Frontiers in immunology (12-08-2021)
    “…In spite of impressive success in treating hematologic malignancies, adoptive therapy with chimeric antigen receptor modified T cells (CAR T) has not yet been…”
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