Search Results - "HUAFENG WEI"
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1
New Approaches to Develop Drug Treatment for Alzheimer's Disease: Targeting Calcium Dysregulation
Published in Current Alzheimer research (01-01-2020)Get more information
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The Role of Calcium Dysregulation in Anesthetic-Mediated Neurotoxicity
Published in Anesthesia and analgesia (01-11-2011)Get full text
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Advancement of supraglottic jet oxygenation and ventilation technique
Published in Indian journal of anaesthesia (01-05-2024)Get full text
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Ryanodine Receptors: A Potential Treatment Target in Various Neurodegenerative Disease
Published in Cellular and molecular neurobiology (01-11-2021)“…Progressive neuronal demise is a key contributor to the key pathogenic event implicated in many different neurodegenerative disorders (NDDs). There are several…”
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Supraglottic jet oxygenation and ventilation (SJOV) for resuscitation of injured soldiers and people in war field
Published in Military medical research (12-04-2022)Get full text
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The Cytoprotective Effects of Dantrolene: A Ryanodine Receptor Antagonist
Published in Anesthesia and analgesia (01-12-2010)“…Calcium, as a second messenger, has an important role in a variety of cellular functions. However, disruption of intracellular calcium homeostasis leads to…”
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Anesthetic neurotoxicity: Apoptosis and autophagic cell death mediated by calcium dysregulation
Published in Neurotoxicology and teratology (01-03-2017)“…Abstract A number of findings suggested that general anesthetics induced neural cell death by apoptosis in various animal models. Although clinical evidence…”
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8
Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma
Published in PloS one (20-02-2013)“…Myeloid-derived suppressor cells (MDSCs) are a heterogeneous family of myeloid cells that suppress T cell immunity in tumor-bearing hosts. In patients with…”
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Isoflurane Causes Greater Neurodegeneration Than an Equivalent Exposure of Sevoflurane in the Developing Brain of Neonatal Mice
Published in Anesthesiology (Philadelphia) (01-06-2010)“…We hypothesized that isoflurane has a greater potency to induce neurodegeneration than sevoflurane in the developing brains of neonatal mice based on our…”
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Dual effects of neuroprotection and neurotoxicity by general anesthetics: Role of intracellular calcium homeostasis
Published in Progress in neuro-psychopharmacology & biological psychiatry (02-12-2013)“…Although general anesthetics have long been considered neuroprotective, there are growing concerns about neurotoxicity. Preclinical studies clearly…”
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Dantrolene : From Malignant Hyperthermia to Alzheimer's Disease
Published in CNS & neurological disorders drug targets (01-01-2019)“…Dantrolene, a ryanodine receptor antagonist, is primarily known as the only clinically acceptable and effective treatment for Malignant Hyperthermia (MH)…”
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Risk factors for pharyngalgia and xerostomia undergoing supraglottic jet oxygenation and ventilation in gastrointestinal endoscopy: a retrospective study
Published in Scientific reports (11-12-2023)“…Supraglottic jet oxygenation/ventilation (SJOV) can reduce hypoxemia in sedated endoscopy but may increase minor side effects like pharyngalgia and xerostomia…”
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Ascites-derived IL-6 and IL-10 synergistically expand CD14 + HLA-DR -/low myeloid-derived suppressor cells in ovarian cancer patients
Published in Oncotarget (29-09-2017)“…Myeloid-derived suppressor cells (MDSC) play a key immunosuppressive role in various types of cancer, including ovarian cancer (OC). In this study, we…”
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Anesthesia, calcium homeostasis and Alzheimer's disease
Published in Current Alzheimer research (01-02-2009)“…While anesthetics are indispensable clinical tools generally safe and effective, in some situations there is grown concern about selective neurotoxicity of…”
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Lung isolation—a personalized and clinically adapted approach to control bronchoscopy-associated acute massive airway hemorrhage
Published in BMC pulmonary medicine (30-11-2023)“…Abstract Background The current concept of bronchoscopy-associated massive airway hemorrhage is not accurate enough, and the amount of bleeding as the only…”
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Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane
Published in PloS one (16-06-2014)“…While previous studies have demonstrated neuronal apoptosis and associated cognitive impairment after isoflurane or propofol exposure in neonatal rodents, the…”
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Intranasal administration of dantrolene increased brain concentration and duration
Published in PloS one (11-03-2020)“…Dantrolene has been demonstrated to be neuroprotective for multiple neurodegenerative diseases. However, dantrolene's limited penetration into the CNS hampers…”
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18
Osteopontin induces autophagy to promote chemo-resistance in human hepatocellular carcinoma cells
Published in Cancer letters (28-12-2016)“…Abstract Hepatocellular carcinoma (HCC) is a major health burden worldwide for its high incidence and mortality. Osteopontin (OPN) is a chemokine-like,…”
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Approaches to Optimizing Dantrolene Neuroprotection for the Treatment of Alzheimer's Disease
Published in Current Alzheimer research (01-01-2020)“…Alzheimer's Disease (AD), a neurodegenerative disorder with high incidence and mortality, is leading its way to the top of the list of the deadliest diseases…”
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PTK7-Targeting CAR T-Cells for the Treatment of Lung Cancer and Other Malignancies
Published in Frontiers in immunology (12-08-2021)“…In spite of impressive success in treating hematologic malignancies, adoptive therapy with chimeric antigen receptor modified T cells (CAR T) has not yet been…”
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