Search Results - "HSU, Ellen"

Biochemical Regulatory Features of Activation-Induced Cytidine Deaminase Remain Conserved from Lampreys to Humans by Quinlan, Emma M., King, Justin J., Amemiya, Chris T., Hsu, Ellen, Larijani, Mani

“…Activation-induced cytidine deaminase (AID) is a genome-mutating enzyme that initiates class switch recombination and somatic hypermutation of antibodies in…”
Get full text

Evidence for Ig Light Chain Isotype Exclusion in Shark B Lymphocytes Suggests Ordered Mechanisms by Iacoangeli, Anna, Lui, Anita, Haines, Ashley, Ohta, Yuko, Flajnik, Martin, Hsu, Ellen

“…Unlike most vertebrates, the shark IgL gene organization precludes secondary rearrangements that delete self-reactive VJ rearranged genes. Nurse sharks express…”
Get full text

Diverse Immunoglobulin Light Chain Organizations in Fish Retain Potential to Revise B Cell Receptor Specificities by Hsu, Ellen, Criscitiello, Michael F

“…We have characterized the genomic organization of the three zebrafish L chain isotypes and found they all differed from those reported in other teleost fishes…”
Get full text

Genome complexity in the coelacanth is reflected in its adaptive immune system by Saha, Nil Ratan, Ota, Tatsuya, Litman, Gary W., Hansen, John, Parra, Zuly, Hsu, Ellen, Buonocore, Francesco, Canapa, Adriana, Cheng, Jan-Fang, Amemiya, Chris T.

“…ABSTRACT We have analyzed the available genome and transcriptome resources from the coelacanth in order to characterize genes involved in adaptive immunity…”
Get full text

Immunoglobulin heavy chain exclusion in the shark by Malecek, Karolina, Lee, Victor, Feng, Wendy, Huang, Jing Li, Flajnik, Martin F, Ohta, Yuko, Hsu, Ellen

“…The adaptive immune system depends on specific antigen receptors, immunoglobulins (Ig) in B lymphocytes and T cell receptors (TCR) in T lymphocytes. Adaptive…”
Get full text

Assembly and Expression of Shark Ig Genes by Hsu, Ellen

“…Sharks are modern descendants of the earliest vertebrates possessing Ig superfamily receptor-based adaptive immunity. They respond to immunogen with Abs that,…”
Get full text

Assembly and expression of shark Ig genes1 by Hsu, Ellen

“…Sharks are modern descendants of the earliest vertebrates possessing Ig superfamily receptor-based adaptive immunity. They respond to immunogen with antibodies…”
Get full text

The invention of lymphocytes by Hsu, Ellen

“…Lamprey and hagfish are surviving representatives of the most ancient vertebrates. They possess adaptive immune systems based on a vast, somatically…”
Get full text

Heavy chain‐only antibody genes in fish evolved to generate unique CDR3 repertoire by Anumukonda, Kamala, Francis, Malcolm, Currie, Peter, Tulenko, Frank, Hsu, Ellen

“…In addition to conventional immunoglobulin, camelids and cartilaginous fish express a special class of antibody that consists only of heavy (H) chain (HCAbs)…”
Get full text

Error-prone DNA repair activity during somatic hypermutation in shark B lymphocytes by Zhu, Catherine, Hsu, Ellen

“…Sharks are representatives of the earliest vertebrates that possess an immune system utilizing V(D)J recombination to generate Ag receptors. Their Ab…”
Get full text

V(D)J recombination: of mice and sharks by Hsu, Ellen

“…The adaptive immune system of jawed vertebrates is based on a vast, anticipatory repertoire of specific antigen receptors, immunoglobulins (Ig) in…”
Get more information

The effect of prior colonic imaging on endoscopic productivity: potential impact of computed tomographic colonography by Hur, Chin, Gazelle, G Scott, Hsu, Ellen H, Halpern, Elkan F, Podolsky, Daniel K

“…If computed tomographic colonography (CTC) is used for primary colorectal cancer (CRC) screening with a small polyp size threshold to define a CTC study as…”
Get more information

ANCA-positive necrotizing vasculitis and thrombotic vasculopathy induced by levamisole-adulterated cocaine: A distinctive clinicopathologic presentation by Jenkins, Jennifer, MD, MPH, Babu, Kavita, MD, Hsu-Hung, Ellen, MD, Robinson-Bostom, Leslie, MD, Kroumpouzos, George, MD, PhD

Get full text

Shark IgW C region diversification through RNA processing and isotype switching by Zhang, Cecilia, Du Pasquier, Louis, Hsu, Ellen

“…Sharks and skates represent the earliest vertebrates with an adaptive immune system based on lymphocyte Ag receptors generated by V(D)J recombination. Shark B…”
Get full text

Artmaking and Alchemy: Examining the Individuation Paths of Jacob Lawrence, Ruth Asawa, and MC Richards by Hsu, Ellen H

“…This hermeneutical study analyzes the lifelong paths to individuation of three noted artists using Jungian and post-Jungian theory: painter Jacob Lawrence,…”
Get full text

Error-prone DNA repair activity during somatic hypermutation in shark B lymphocytes1 by Zhu, Catherine, Hsu, Ellen

“…Sharks are representatives of the earliest vertebrates that possess an immune system utilizing V(D)J recombination to generate antigen receptors. Their…”
Get full text

Shark IgW C region diversification through RNA processing and isotype switching1 by Zhang, Cecilia, Du Pasquier, Louis, Hsu, Ellen

“…Sharks and skates represent the earliest vertebrates with an adaptive immune system based on lymphocyte antigen receptors generated by V(D)J recombination…”
Get full text

Biased Immunoglobulin Light Chain Gene Usage in the Shark by Iacoangeli, Anna, Lui, Anita, Naik, Ushma, Ohta, Yuko, Flajnik, Martin, Hsu, Ellen

“…This study of a large family of κ L chain clusters in nurse shark completes the characterization of its classical Ig gene content (two H chain isotypes, μ and…”
Get full text

Biased immunoglobulin light chain gene usage in the shark1 by Iacoangeli, Anna, Lui, Anita, Naik, Ushma, Ohta, Yuko, Flajnik, Martin, Hsu, Ellen

“…This study of a large family of kappa light (L) chain clusters in nurse shark completes the characterization of its classical immunoglobulin (Ig) gene content…”
Get full text

Origin of Immunoglobulin Isotype Switching by Zhu, Catherine, Lee, Victor, Finn, Alyssa, Senger, Kate, Zarrin, Ali A., Du Pasquier, Louis, Hsu, Ellen

“…From humans to frogs, immunoglobulin class switching introduces different effector functions to antibodies through an intrachromosomal DNA recombination…”
Get full text