Search Results - "HRAMIAK, Irene"

Allogenic Fecal Microbiota Transplantation in Patients With Nonalcoholic Fatty Liver Disease Improves Abnormal Small Intestinal Permeability: A Randomized Control Trial by Craven, Laura, Rahman, Adam, Nair Parvathy, Seema, Beaton, Melanie, Silverman, Justin, Qumosani, Karim, Hramiak, Irene, Hegele, Rob, Joy, Tisha, Meddings, Jon, Urquhart, Brad, Harvie, Ruth, McKenzie, Charles, Summers, Kelly, Reid, Gregor, Burton, Jeremy P., Silverman, Michael

“…Nonalcoholic fatty liver disease (NAFLD) is an obesity-related disorder that is rapidly increasing in incidence and is considered the hepatic manifestation of…”
Get full text

Sodium‐glucose co‐transporter inhibitors, their role in type 1 diabetes treatment and a risk mitigation strategy for preventing diabetic ketoacidosis: The STOP DKA Protocol by Goldenberg, Ronald M., Gilbert, Jeremy D., Hramiak, Irene M., Woo, Vincent C., Zinman, Bernard

“…Recent phase 3 clinical trials have evaluated the impact of adding sodium‐glucose co‐transporter (SGLT) inhibitors to the type 1 diabetes armamentarium. These…”
Get full text

Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial by Leiter, Lawrence A, Bain, Stephen C, Hramiak, Irene, Jódar, Esteban, Madsbad, Sten, Gondolf, Theis, Hansen, Thomas, Holst, Ingrid, Lingvay, Ildiko

“…The SUSTAIN 6 trial demonstrated that once-weekly semaglutide (0.5 and 1.0 mg) significantly reduced major adverse cardiovascular (CV) events (MACE) vs placebo…”
Get full text

Effectiveness of Nonmydriatic Ultra-Widefield Retinal Imaging to Screen for Diabetic Eye Disease: A Randomized Controlled Trial (Clearsight) by Liu, Selina L, Gonder, John R, Owrangi, Ehsan, Klar, Neil S, Hramiak, Irene M, Uvarov, Artem, Mahon, Jeffrey L

“…Suboptimal diabetic eye disease screening is a major cause of preventable vision loss. Screening barriers include mydriasis and the need for dedicated…”
Get full text

Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial by Ismail-Beigi, Faramarz, Dr, Craven, Timothy, MSPH, Banerji, Mary Ann, MD, Basile, Jan, MD, Calles, Jorge, MD, Cohen, Robert M, MD, Cuddihy, Robert, MD, Cushman, William C, MD, Genuth, Saul, MD, Grimm, Richard H, MD, Hamilton, Bruce P, MD, Hoogwerf, Byron, MD, Karl, Diane, MD, Katz, Lois, MD, Krikorian, Armand, MD, O'Connor, Patrick, MD, Pop-Busui, Rodica, MD, Schubart, Ulrich, MD, Simmons, Debra, MD, Taylor, Harris, MD, Thomas, Abraham, MD, Weiss, Daniel, MD, Hramiak, Irene, MD

“…Summary Background Hyperglycaemia is associated with increased risk of cardiovascular complications in people with type 2 diabetes. We investigated whether…”
Get full text

Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis by Buckingham, Bruce A, Raghinaru, Dan, Cameron, Fraser, Bequette, B Wayne, Chase, H Peter, Maahs, David M, Slover, Robert, Wadwa, R Paul, Wilson, Darrell M, Ly, Trang, Aye, Tandy, Hramiak, Irene, Clarson, Cheril, Stein, Robert, Gallego, Patricia H, Lum, John, Sibayan, Judy, Kollman, Craig, Beck, Roy W

“…Nocturnal hypoglycemia can cause seizures and is a major impediment to tight glycemic control, especially in young children with type 1 diabetes. We conducted…”
Get full text

2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children [summary] by Lau, David C W, Douketis, James D, Morrison, Katherine M, Hramiak, Irene M, Sharma, Arya M, Ur, Ehud

“…Oded Bar-Or (deceased), Professor Emeritus of Pediatrics, McMaster University, and Director of the Children's Exercise and Nutrition Centre, Chedoke Hospital,…”
Get full text

A Randomized Trial of a Home System to Reduce Nocturnal Hypoglycemia in Type 1 Diabetes by MAAHS, David M, CALHOUN, Peter, SLOVER, Robert, PAUL WADWA, R, WILSON, Darrell M, KOLLMAN, Craig, BECK, Roy W, BUCKINGHAM, Bruce A, PETER CHASE, H, HRAMIAK, Irene, LUM, John, CAMERON, Fraser, WAYNE BEQUETTE, B, AYE, Tandy, PAUL, Terri

“…Overnight hypoglycemia occurs frequently in individuals with type 1 diabetes and can result in loss of consciousness, seizure, or even death. We conducted an…”
Get full text

Effect of Semaglutide on Regression and Progression of Glycemia in People With Overweight or Obesity but Without Diabetes in the SELECT Trial by Kahn, Steven E, Deanfield, John E, Jeppesen, Ole Kleist, Emerson, Scott S, Boesgaard, Trine Welløv, Colhoun, Helen M, Kushner, Robert F, Lingvay, Ildiko, Burguera, Bartolome, Gajos, Grzegorz, Horn, Deborah Bade, Hramiak, Irene M, Jastreboff, Ania M, Kokkinos, Alexander, Maeng, Michael, Matos, Ana Laura S A, Tinahones, Francisco J, Lincoff, A Michael, Ryan, Donna H

“…To determine whether semaglutide slows progression of glycemia in people with cardiovascular disease and overweight or obesity but without diabetes. In a…”
Get full text

Trends in Antihyperglycemic Medication Prescriptions and Hypoglycemia in Older Adults: 2002-2013 by Clemens, Kristin K, Shariff, Salimah, Liu, Kuan, Hramiak, Irene, Mahon, Jeffrey L, McArthur, Eric, Garg, Amit X

“…Over the last decade, several new antihyperglycemic medications have been introduced including those associated with a lower hypoglycemia risk. We aimed to…”
Get full text

Glycated Hemoglobin Level Goal Achievement in Adults With Type 2 Diabetes in Canada: Still Room for Improvement by Leiter, Lawrence A., Cheng, Alice Y.Y., Ekoé, Jean-Marie, Goldenberg, Ronald M., Harris, Stewart B., Hramiak, Irene M., Khunti, Kamlesh, Lin, Peter J., Richard, Jean-François, Senior, Peter A., Yale, Jean-François, Goldin, Lianne, Tan, Mary K., Langer, Anatoly

“…To describe the clinical histories and management of adults with type 2 diabetes who were not reaching their target glycated hemoglobin (A1C) levels and to…”
Get full text

A randomised trial of non-mydriatic ultra-wide field retinal imaging versus usual care to screen for diabetic eye disease: rationale and protocol for the Clearsight trial by Liu, Selina L, Mahon, Lewis W, Klar, Neil S, Schulz, David C, Gonder, John R, Hramiak, Irene M, Mahon, Jeffrey L

“…IntroductionSuboptimal screening for diabetic eye disease is a major cause of preventable vision loss. Screening barriers include mydriasis and the extra time…”
Get full text

The Hypoglycemic Risk of Glyburide (Glibenclamide) Compared with Modified-Release Gliclazide by Clemens, Kristin K., MD, McArthur, Eric, MSc, Dixon, Stephanie N., PhD, Fleet, Jamie L., BHSc, Hramiak, Irene, MD, Garg, Amit X., MD

“…Abstract Objectives The risk for hypoglycemia when taking glyburide compared with modified-release gliclazide remains to be established in older adults in…”
Get full text

Severe Hypoglycemia Monitoring and Risk Management Procedures in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial by Bonds, Denise E., MD, MPH, Kurashige, Ella Mae, MSN, RN, Bergenstal, Richard, MD, Brillon, David, MD, Domanski, Michael, MD, Felicetta, James V., MD, Fonseca, Vivian A., MD, Hall, Kathleen, MD, MPH, Hramiak, Irene, MD, Miller, Michael E., PhD, Osei, Kwame, MD, Simons-Morton, Denise G., MD, PhD

“…Hypoglycemia is a potentially serious side effect of blood glucose lowering in diabetes mellitus. The intensive glycemia treatment arm of the Action to Control…”
Get full text

The Hypoglycemic Risk of Glyburide (Glibenclamide) Compared with Modified-Release Gliclazide by Clemens, Kristin K., MD, McArthur, Eric, MSc, Dixon, Stephanie N., PhD, Fleet, Jamie L., BHSc, Hramiak, Irene, MD, Garg, Amit X., MD

“…Abstract Objectives The risk for hypoglycemia when taking glyburide compared with modified-release gliclazide remains to be established in older adults in…”
Get full text

Fast-Acting Insulin Aspart and the Need for New Mealtime Insulin Analogues in Adults With Type 1 and Type 2 Diabetes: A Canadian Perspective by Senior, Peter, Hramiak, Irene

“…Limiting postprandial glucose (PPG) excursions is an important aspect of overall glycemic control. Rapid-acting insulin analogues (RAIAs) aim to mimic the…”
Get full text

Acute Management and Outcomes of Patients with Diabetes Mellitus Presenting to Canadian Emergency Departments with Hypoglycemia by Rowe, Brian H., MD, MSc, Singh, Mira, MA, Villa-Roel, Cristina, MD, MSc, Leiter, Lawrence A., MD, Hramiak, Irene, MD, Edmonds, Marcia L., MD, MSc, Lang, Eddy, MD, Sivilotti, Marco, MD, MSc, Scheuermeyer, Frank, MD, Worster, Andrew, MD, MSc, Riley, Jennifer, MD, Afilalo, Marc, MD, Stiell, Ian, MD, MSc, Yale, Jean-Francois, MD, Woo, Vincent C., MD, Campbell, Samuel, MD

“…Abstract Objectives This retrospective chart audit examined the demographics, investigations, management and outcomes of adult patients with diabetes mellitus…”
Get full text

Heterogeneity of nuclear lamin A mutations in Dunnigan-type familial partial lipodystrophy by HEGELE, Robert A, HENIAN CAO, ANDERSON, Carol M, HRAMIAK, Irene M

“…We previously identified a novel mutation, namely LMNA R482Q, that was found to underlie Dunnigan-type partial lipodystrophy (FPLD) and diabetes in an extended…”
Get full text

The risk of pancreatitis with sitagliptin therapy in older adults: a population-based cohort study by Clemens, Kristin K., MD, McArthur, Eric, MSc, Fleet, Jamie L., BHSc, Hramiak, Irene, MD, Garg, Amit X., MD, PhD

“…Background The risk of pancreatitis with sitagliptin use in routine care remains to be established in older patients. We aimed to determine this risk in older…”
Get full text

Acute Management and Outcomes of Patients with Diabetes Mellitus Presenting to Canadian Emergency Departments with Hypoglycemia by Rowe, Brian H., MD, MSc, Singh, Mira, MA, Villa-Roel, Cristina, MD, MSc, Leiter, Lawrence A., MD, Hramiak, Irene, MD, Edmonds, Marcia L., MD, MSc, Lang, Eddy, MD, Sivilotti, Marco, MD, MSc, Scheuermeyer, Frank, MD, Worster, Andrew, MD, MSc, Riley, Jennifer, MD, Afilalo, Marc, MD, Stiell, Ian, MD, MSc, Yale, Jean-Francois, MD, Woo, Vincent C., MD, Campbell, Samuel, MD

“…Abstract Objectives This retrospective chart audit examined the demographics, investigations, management and outcomes of adult patients with diabetes mellitus…”
Get full text