Search Results - "HRADSKY, O."

Comparison of laparoscopic and open ileocecal resection for Crohn’s disease in children by Dotlacil, V., Lerchova, T., Coufal, S., Kucerova, B., Schwarz, J., Hradsky, O., Skaba, R., Rygl, M.

“…Purpose Ileocecal resection (ICR) is the most frequently performed surgery in paediatric Crohn’s disease (CD) patients. The aim of the study was to compare…”
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Substantial proportion of MODY among multiplex families participating in a Type 1 diabetes prediction programme by Petruzelkova, L., Dusatkova, P., Cinek, O., Sumnik, Z., Pruhova, S., Hradsky, O., Vcelakova, J., Lebl, J., Kolouskova, S.

“…Aims Patients with maturity‐onset diabetes of the young (MODY) might be over‐represented in families with histories of Type 1 diabetes. Our aim was to…”
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Pilot study: Association between Helicobacter pylori in adenoid hyperplasia and reflux episodes detected by multiple intraluminal impedance in children by Katra, R, Kabelka, Z, Jurovcik, M, Hradsky, O, Kraus, J, Pavlik, E, Nartova, E, Lukes, P, Astl, J

“…Abstract Objectives The aim of this pilot study was to investigate an association between laryngopharyngeal reflux detected by combined multiple intraluminal…”
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Infliximab dependency in children with Crohn’s disease by DURICOVA, D., PEDERSEN, N., LENICEK, M., HRADSKY, O., BRONSKY, J., ADAMCOVA, M., ELKJAER, M., ANDERSEN, P. S., VITEK, L., LARSEN, K., LUKAS, M., NEVORAL, J., WEWER, V., MUNKHOLM, P.

“…Summary Background  Recently, infliximab dependency has been described. Aim  To assess frequency of ID in 82 consecutive Crohn’s disease children treated with…”
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P-104: Duration of remission in children with Crohn’s disease treated initially with corticosteroids or exclusive enteral nutrition by Hradsky, O.

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P853 Factors associated with intestinal tissue levels of anti-TNF in pediatric patients with Crohn's Disease by Dotlacil, V, Coufal, S, Lerchova, T, Zarubova, K, Kucerova, B, Tlaskalova-Hogenova, H, Kverka, M, Bronsky, J, Skaba, R, Hradsky, O, Rygl, M

“…Abstract Background Despite advancements, understanding the tissue pharmacokinetics of Anti-tumour necrosis factor alpha monoclonal antibodies (aTNF) and…”
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Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn Disease (the Speed-up Study): A Multicenter Study from the Pediatric IBD Porto Group of ESPGHAN by Yerushalmy-Feler, Anat, Pujol-Muncunill, Gemma, Martin-de-Carpi, Javier, Kolho, Kaija-Leena, Levine, Arie, Olbjørn, Christine, Granot, Maya, Bramuzzo, Matteo, Rolandsdotter, Helena, Mouratidou, Natalia, Hradsky, Ondrej, Scarallo, Luca, Matar, Manar, Rimon, Ramit Magen, Rinawi, Firas, Shalem, Tzippi, Najajra, Hisham, de Meij, Tim, Aloi, Marina, Rodríguez-Belvís, Marta Velasco, Alvisi, Patrizia, Schneider, Anna-Maria, van Rheenen, Patrick, Navas-López, Víctor Manuel, Kiparissi, Fevronia, Barrio, Josefa, Turner, Dan, Cohen, Shlomi

“…Escalation of the ustekinumab (UST) maintenance dosage was effective in adults with Crohn disease (CD), but no data are available for children. We evaluated…”
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P1130 Predictors of Remission within One Year of Advanced Therapy in Paediatric Patients with Ulcerative Colitis – analysis from Czech national registry of biologic treatment (CREdIT) by Hradsky, O, Copova, I, Durilova, M, Kazeka, D, Lerchova, T, Mitrova, K, Zarubova, K, Vlckova, E, Schwarz, J, El-Lababidi, N, Karaskova, E, Veghova-Velganova, M, Melek, J, Sulakova, A, Gonsorcikova, L, Sobotkova, M, Zeniskova, I, Zimen, M, Bronsky, J, Bortlik, M

“…Abstract Background Data on the outcomes of advanced therapy in paediatric patients with ulcerative colitis (UC) and their predictors are scarce. We aim to…”
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P119 The immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa facilitates diagnosis of paediatric ulcerative colitis by Fabian, O, Hradsky, O, Drskova, T, Mikus, F, Zamecnik, J, Bronsky, J

“…Abstract Background Diagnosis of paediatric inflammatory bowel diseases (IBD) remains challenging. We aimed at evaluated the value of immunohistochemical…”
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Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn Disease (the Speed‐up Study) by Yerushalmy‐Feler, Anat, Pujol‐Muncunill, Gemma, Martin‐de‐Carpi, Javier, Kolho, Kaija‐Leena, Levine, Arie, Olbjørn, Christine, Granot, Maya, Bramuzzo, Matteo, Rolandsdotter, Helena, Mouratidou, Natalia, Hradsky, Ondrej, Scarallo, Luca, Matar, Manar, Rimon, Ramit Magen, Rinawi, Firas, Shalem, Tzippi, Najajra, Hisham, Meij, Tim, Aloi, Marina, Rodríguez‐Belvís, Marta Velasco, Alvisi, Patrizia, Schneider, Anna‐Maria, Rheenen, Patrick, Navas‐López, Víctor Manuel, Kiparissi, Fevronia, Barrio, Josefa, Turner, Dan, Cohen, Shlomi

“…Objectives: Escalation of the ustekinumab (UST) maintenance dosage was effective in adults with Crohn disease (CD), but no data are available for children. We…”
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P458 Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn’s disease (the SPEED-UP study) - A multi-center study from the paediatric IBD Porto group of ESPGHAN by Yerushalmy-Feler, A, Pujol-Muncunill, G, Martin-de-Carpi, J, Kolho, K L, Levine, A, Olbjørn, C, Granot, M, Bramuzzo, M, Jonsson Rolandsdotter, H, Mouratidou, N, Hradsky, O, Scarallo, L, Matar, M, Magen Rimon, R, Rinawi, F, Shalem, T, Najajra, H, de Meij, T, Aloi, M, Velasco Rodríguez-Belvís, M, Alvisi, P, Schneider, A M, van Rheenen, P, Navas-López, V M, Kiparissi, F, Barrio, J, Turner, D, Cohen, S

“…Abstract Background Ustekinumab (UST) is an effective therapy for induction and maintenance of remission in Crohn’s disease (CD). Intensification of UST…”
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P365 Identification of predictive factors of AZA/6-MP treatment outcome in paediatric luminal Crohn’s disease: a multicentre study of the paediatric IBD Porto group of ESPGHAN by LERCHOVA, T, Hradsky, O, Kulich, M, Veres, G, Dias, J A, Sladek, M, Kolacek, S, Van Biervliet, S, Melek, J, Serban, D, Winther, K, de Meij, T, Schwarz, J, Kolho, K L, Escher, J C, Bronsky, J

“…Abstract Background According to current guidelines, most paediatric patients in Europe diagnosed with Crohn′s disease (CD) are prescribed long-term…”
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P432 Therapeutic approaches for perianal fistula in paediatric and adolescent onset Crohn's disease – a multicentre cohort study by Sebastian, S., Tzivinikos, C., Drskova, T., Hradsky, O., Nair, M.V., Sahnan, K., Muhammed, R., Devadason, D., Parmar, R.S., Crook, K., Akbar, A., Thomson, M., Hart, A.L.

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P460 Impact of anti-TNFα exposure during pregnancy for maternal inflammatory bowel disease on serologic response to vaccination of exposed children by Duricová, D, Dvorakova, E, Kozeluhova, J, Kohout, P, Mitrova, K, Durilova, M, Zarubova, K, Hradsky, O, Bronsky, J, Hradska, N, Bronska, E, Machkova, N, Hruba, V, Bortlik, M, Lukas, M, Malickova, K

“…Abstract Background Anti-TNFα therapy is increasingly used during pregnancy for women with inflammatory bowel disease (IBD). Thus, the knowledge on long-term…”
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P734 Anti-TNFa exposure during pregnancy is not associated with increased infection risk in exposed children during the first year of life by Duricová, D, Dvorakova, E, Kozeluhova, J, Kohout, P, Mitrova, K, Durilova, M, Zarubova, K, Hradsky, O, Bronsky, J, Hradska, N, Bronska, E, Machkova, N, Hruba, V, Bortlik, M, Lukas, M, Malickova, K

“…Abstract Background There has already been a solid evidence on safety of anti-TNFa therapy on foetal development and newborn outcome. However, there is still a…”
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Safety and Potential Efficacy of Escalating Dose of Ustekinumab in Pediatric Crohn's disease (the SPEED-UP study) - A multi-center study from the paediatric IBD Porto group of ESPGHAN by Yerushalmy-Feler, A, Pujol-Muncunill, G, Martin-De-Carpi, J, Kolho, KL, Levine, A, Olbjorn, C, Granot, M, Bramuzzo, M, Rolandsdotter, HJ, Mouratidou, N, Hradsky, O, Scarallo, L, Matar, M, Rimon, RM, Rinawi, F, Shalem, T, Najajra, H, de Meij, T, Aloi, M, Rodriguez-Belvis, MV, Alvisi, P, Schneider, AM, Van Rheenen, P, Navas-Lopez, VM, Kiparissi, F, Barrio, J, Turner, D, Cohen, S

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Variants of CARD15, TNFA and PTPN22 and susceptibility to Crohn's disease in the Czech population: high frequency of the CARD15 1007fs by Hradsky, O., Lenicek, M., Dusatkova, P., Bronsky, J., Nevoral, J., Valtrova, V., Kotalova, R., Szitanyi, P., Petro, R., Starzykova, V., Bortlik, M., Vitek, L., Lukas, M., Cinek, O.

“…Crohn’s disease (CD) has been shown to be associated with the variants in the CARD15 gene as well as in other genes involved in the immune response. The…”
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P211 Differences in therapeutic approaches and outcomes in paediatric and adult onset Crohn's disease with perianal fistula: comparison of 2 multicentre fistula cohorts by Sebastian, S., Black, C., Nair, M.V., Drskova, T., Hradsky, O., Tzivinikos, C., Sahnan, K., Muhammed, R., Devadason, D., Parmar, R.S., Crook, K., Akbar, A., Thomson, M., Pugliese, D., Armuzzi, A., Katsanos, K.H., Christodoulou, D.K., Selinger, C., Maconi, G., Fiorino, G., Kopylov, U., Bosca-Watts, M.M., Karmiris, K., Ellul, P., Ben-Horin, S., Danese, S., Hart, A.L.

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P1215 Blastocystis is very rare in faeces of children with Crohn’s disease: quantity, subtyping and association with the faecal bacteriome by Hurych, J, Hlináková, L, Lerchová, T, Kubát, M, Malcová, H, Cebecauerová, D, Hradský, O, Bronský, J, Cinek, O

“…Abstract Background Blastocystis is a single-cell gut protist, presumably an indicator of gut health. We aimed to assess its occurrence and subtypes in a…”
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P911 The changes in the faecal microbiome and metabolome in Crohn’s disease after treatment with anti-TNFα antibodies are of secondary origin by Hurych, J, Mascellani Bergo, A, Lerchová, T, Hlináková, L, Kubát, M, Malcová, H, Cebecauerová, D, Schwarz, J, Karásková, E, Hecht, T, Vyhnánek, R, Ťoukálková, L, Dotlačil, V, Kobrová, K, Čížková, A, Horváth, R, Bronsky, J, Havlík, J, Hradský, O, Cinek, O

“…Abstract Background Treatment by anti-TNFα antibodies (aTNFα) is known to change the dysbiotic faecal bacteriome in Crohn’s disease (CD). However, whether the…”
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