Search Results - "HOZUMI, YASUO"

Taxanes versus S-1 as the first-line chemotherapy for metastatic breast cancer (SELECT BC): an open-label, non-inferiority, randomised phase 3 trial by Takashima, Tsutomu, MD, Mukai, Hirofumi, Dr, Hara, Fumikata, MD, Matsubara, Nobuaki, MD, Saito, Tsuyoshi, MD, Takano, Toshimi, MD, Park, Youngjin, Prof, Toyama, Tatsuya, Prof, Hozumi, Yasuo, MD, Tsurutani, Junji, MD, Imoto, Shigeru, Prof, Watanabe, Takanori, MD, Sagara, Yoshiaki, MD, Nishimura, Reiki, MD, Shimozuma, Kojiro, Prof, Ohashi, Yasuo, Prof

“…Summary Background Oral fluoropyrimidines are used for the first-line treatment of metastatic breast cancer to avoid severe adverse effects, although firm…”
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Anthracycline-containing regimens or taxane versus S-1 as first-line chemotherapy for metastatic breast cancer by Mukai, Hirofumi, Uemura, Yukari, Akabane, Hiromitsu, Watanabe, Takanori, Park, Youngjin, Takahashi, Masato, Sagara, Yoshiaki, Nishimura, Reiki, Takashima, Tsutomu, Fujisawa, Tomomi, Hozumi, Yasuo, Kawahara, Takuya

“…Background We have previously demonstrated S-1 is non-inferior to taxane with respect to overall survival as first-line chemotherapy for HER2-negative…”
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A Case of Triple-Negative Breast Cancer with Germline Pathogenic Variants in Both BRCA1 and BRCA2 by Kitahara, Miyuki, Hozumi, Yasuo, Machinaga, Mitsuki, Hayashi, Yuka

“…Abstract We report a rare case of hereditary breast and ovarian cancer syndrome (HBOC) with pathogenic variants in both BRCA1 and BRCA2. The patient was a…”
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Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): a randomised phase 3 trial by van de Velde, Cornelis JH, Prof, Rea, Daniel, MD, Seynaeve, Caroline, MD, Putter, Hein, Prof, Hasenburg, Annette, Prof, Vannetzel, Jean-Michel, MD, Paridaens, Robert, Prof, Markopoulos, Christos, Prof, Hozumi, Yasuo, MD, Hille, Elysee TM, PhD, Kieback, Dirk G, MD, Asmar, Lina, PhD, Smeets, Jan, BSc, Nortier, Johan WR, Prof, Hadji, Peyman, Prof, Bartlett, John MS, PhD, Jones, Stephen E, MD

“…Summary Background Aromatase inhibitors improved disease-free survival compared with tamoxifen when given as an initial adjuvant treatment or after 2–3 years…”
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Ki-67 response-guided preoperative chemotherapy for HER2-positive breast cancer: results of a randomised Phase 2 study by Mukai, Hirofumi, Yamaguchi, Takeshi, Takahashi, Masato, Hozumi, Yasuo, Fujisawa, Tomomi, Ohsumi, Shozo, Akabane, Hiromitsu, Nishimura, Reiki, Takashima, Tsutomu, Park, Youngjin, Sagara, Yasuaki, Toyama, Tatsuya, Imoto, Shigeru, Mizuno, Toshiro, Yamashita, Satoshi, Fujii, Satoshi, Uemura, Yukari

“…Background The effectiveness of a therapeutic strategy that switches chemotherapy, based on Ki-67 tumour expression after initial therapy, relative to that of…”
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Cost-effectiveness analysis of the introduction of S-1 therapy for first-line metastatic breast cancer treatment in Japan: results from the randomized phase III SELECT BC trial by Shiroiwa, Takeru, Fukuda, Takashi, Shimozuma, Kojiro, Mouri, Mitsuko, Hagiwara, Yasuhiro, Kawahara, Takuya, Ohsumi, Shozo, Hozumi, Yasuo, Sagara, Yoshiaki, Ohashi, Yasuo, Mukai, Hirofumi

“…This study evaluated the cost-effectiveness of replacing standard intravenous therapy (taxane) with oral S-1 therapy for first-line metastatic breast cancer…”
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Preoperative concurrent endocrine therapy with chemotherapy in luminal B-like breast cancer by Matsunuma, Ryoichi, Watanabe, Toru, Hozumi, Yasuo, Koizumi, Kei, Ito, Yasushi, Maruyama, Shoko, Ogura, Hiroyuki, Goto, Keigo, Mori, Hiroki, Sawai, Noriko, Shiiya, Norihiko

“…Purpose Luminal B-like breast cancer is sensitive to both chemotherapy and endocrine therapy. We aimed to assess the safety and efficacy of concomitant…”
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Sentinel lymph node biopsy in patients with breast cancer using superparamagnetic iron oxide and a magnetometer by Shiozawa, Mikio, Lefor, Alan T., Hozumi, Yasuo, Kurihara, Katsumi, Sata, Naohiro, Yasuda, Yoshikazu, Kusakabe, Moriaki

“…Background Some hospitals lack facilities for radioisotopes in sentinel node biopsy. A novel method is used with a superparamagnetic tracer and a magnetometer…”
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Bowen’s Disease of the Nipple by Kitahara, Miyuki, Hozumi, Yasuo, Watanabe, Akie , Iijima, Tatsuo

“…Bowen’s disease is a type of intraepidermal squamous cell carcinoma that commonly develops in areas of the skin exposed to sunlight, such as the scalp, trunk,…”
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Impact of immunohistological subtypes on the long-term prognosis of patients with metastatic breast cancer by Kobayashi, Kokoro, Ito, Yoshinori, Matsuura, Masaaki, Fukada, Ippei, Horii, Rie, Takahashi, Shunji, Akiyama, Futoshi, Iwase, Takuji, Hozumi, Yasuo, Yasuda, Yoshikazu, Hatake, Kiyohiko

“…Purpose Although improved long-term prognoses for patients with metastatic breast cancer (MBC) have been demonstrated, few reports address overall survival…”
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Factors affecting enrollment in randomized controlled trials conducted for patients with metastatic breast cancer by Ohsumi, Shozo, Mukai, Hirofumi, Takahashi, Masato, Hozumi, Yasuo, Akabane, Hiromitsu, Park, Youngjin, Tokunaga, Eriko, Takashima, Tsutomu, Watanabe, Takanori, Sagara, Yoshiaki, Kaneko, Tetsuji, Ohashi, Yasuo

“…It is critical to obtain informed consent from eligible patients to complete clinical trials. We investigated the factors that affect the participation rates…”
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Specific Adverse Events Predict Survival Benefit in Patients Treated With Tamoxifen or Aromatase Inhibitors: An International Tamoxifen Exemestane Adjuvant Multinational Trial Analysis by FONTEIN, Duveken B. Y, SEYNAEVE, Caroline, MARKOPOULOS, Christos, HOZUMI, Yasuo, BARTLETT, John M. S, JONES, Stephen E, REA, Daniel William, NORTIER, Johan W. R, DE VELDE, Cornelis J. H. Van, HADJI, Peyman, HILLE, Elysée T. M, DE WATER, Willemien Van, PUTTER, Hein, KRANENBARG, Elma Meershoek-Klein, HASENBURG, Annette, PARIDAENS, Robert J, VANNETZEL, Jean-Michel

“…Specific adverse events (AEs) associated with endocrine therapy and related to depletion or blocking of circulating estrogens may be related to treatment…”
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Invasive Cancer Confined to the Nipple of the Conserved Breast: A Case Report by Kitahara, Miyuki, Hozumi, Yasuo, Takeuchi, Naoto, Ichinohe, Satoko, Machinaga, Mitsuki, Iijima, Tatsuo

“…Invasive breast cancer deriving from the milk duct and lobule that develops in the nipple is extremely rare, except in Paget’s disease and skin cancer. This is…”
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Prognostic factors of HER2-positive breast cancer patients who develop brain metastasis: a multicenter retrospective analysis by Hayashi, Naoki, Niikura, Naoki, Masuda, Norikazu, Takashima, Seiki, Nakamura, Rikiya, Watanabe, Ken-ichi, Kanbayashi, Chizuko, Ishida, Mayumi, Hozumi, Yasuo, Tsuneizumi, Michiko, Kondo, Naoto, Naito, Yoichi, Honda, Yayoi, Matsui, Akira, Fujisawa, Tomomi, Oshitanai, Risa, Yasojima, Hiroyuki, Yamauchi, Hideko, Saji, Shigehira, Iwata, Hiroji

“…The clinical course and prognostic factors of HER2-positive breast cancer patients with brain metastases are not well known because of the relatively small…”
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Predictive Factors and Value of ypN+ after Neoadjuvant Chemotherapy in Clinically Lymph Node-Negative Breast Cancer by Fukada, Ippei, Araki, Kazuhiro, Kobayashi, Kokoro, Shibayama, Tomoko, Takahashi, Shunji, Horii, Rie, Akiyama, Futoshi, Iwase, Takuji, Ohno, Shinji, Hatake, Kiyohiko, Hozumi, Yasuo, Sata, Naohiro, Ito, Yoshinori

“…Pathological complete response (pCR) with neoadjuvant chemotherapy (NAC) has been regarded as a surrogate endpoint for disease-free survival (DFS) and overall…”
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Effect of early dose increase of evocalcet for intractable hypercalcemia caused by parathyroid carcinoma by Morishita, Azusa, Hozumi, Yasuo, Ishii, Hiroaki, Hokazono, Yukio, Manuel Yosei Kikuchi, Clovis, Shimasaki, Megumi, Itaya, Mikiko, Oura, Masaharu, Kuriki, Ken, Hishida, Akira, Seki, George

“…Summary Hypercalcemia due to parathyroid carcinoma (PC) is safely and quickly controlled with rapidly increasing evocalcet doses. Most parathyroid carcinomas…”
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Significance of participation of global clinical trial by Hozumi, Yasuo

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Distant Metastasis after Surgery for Encapsulated Papillary Carcinoma of the Breast: A Case Report by Kitahara, Miyuki, Hozumi, Yasuo, Takeuchi, Naoto, Ichinohe, Satoko, Fujiwara, Saori, Machinaga, Mitsuki, Saitoh, Hitoaki, Iijima, Tatsuo

“…In the absence of clear interstitial invasion, encapsulated papillary carcinoma (EPC) of the breast may be attributed to an extremely good prognosis if handled…”
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Pathological responses and survival of patients with human epidermal growth factor receptor 2-positive breast cancer who received neoadjuvant chemotherapy including trastuzumab by Ohzawa, Hideyuki, Sakatani, Takashi, Niki, Toshiro, Yasuda, Yoshikazu, Hozumi, Yasuo

“…Background The effectiveness of neoadjuvant chemotherapy is evaluated on the basis of pathological responses and survival outcome, because achievement of a…”
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HER2-Positive Conversion in a Metastatic Liver Focus in Late Recurrent Breast Cancer by Kitahara, Miyuki, Hozumi, Yasuo, Nakamura, Ayaka, Tachi, Kana, Saitoh, Hitoaki, Iijima, Tatsuo

“…Late recurrence of estrogen receptor (ER) positive breast cancer is common. When tissues from a recurrent or metastatic focus are available, re-evaluation of…”
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