Search Results - "HOWE, James R"

Management of Cancer Surgery Cases During the COVID-19 Pandemic: Considerations by Bartlett, David L., Howe, James R., Chang, George, Crago, Aimee, Hogg, Melissa, Karakousis, Giorgos, Levine, Edward, Maker, Ajay, Mamounas, Eleftherios, McGuire, Kandace, Merchant, Nipun, Shibata, David, Sohn, Vance, Solorzano, Carmen, Turaga, Kiran, White, Richard, Yang, Anthony, Yoon, Sam

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The North American Neuroendocrine Tumor Society Consensus Paper on the Surgical Management of Pancreatic Neuroendocrine Tumors by Howe, James R., Merchant, Nipun B., Conrad, Claudius, Keutgen, Xavier M., Hallet, Julie, Drebin, Jeffrey A., Minter, Rebecca M., Lairmore, Terry C., Tseng, Jennifer F., Zeh, Herbert J., Libutti, Steven K., Singh, Gagandeep, Lee, Jeffrey E., Hope, Thomas A., Kim, Michelle K., Menda, Yusuf, Halfdanarson, Thorvardur R., Chan, Jennifer A., Pommier, Rodney F.

“…This manuscript is the result of the North American Neuroendocrine Tumor Society consensus conference on the surgical management of pancreatic neuroendocrine…”
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Appropriate Use Criteria for Somatostatin Receptor PET Imaging in Neuroendocrine Tumors by Hope, Thomas A, Bergsland, Emily K, Bozkurt, Murat Fani, Graham, Michael, Heaney, Anthony P, Herrmann, Ken, Howe, James R, Kulke, Matthew H, Kunz, Pamela L, Mailman, Josh, May, Lawrence, Metz, David C, Millo, Corina, O'Dorisio, Sue, Reidy-Lagunes, Diane L, Soulen, Michael C, Strosberg, Jonathan R

“…Somatostatin receptor (SSTR) PET has demonstrated a significant improvement over conventional imaging (CI) in patients with neuroendocrine tumors (NETs). SSTR…”
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The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Pancreatic Neuroendocrine Tumors by Halfdanarson, Thorvardur R., Strosberg, Jonathan R., Tang, Laura, Bellizzi, Andrew M., Bergsland, Emily K., O'Dorisio, Thomas M., Halperin, Daniel M., Fishbein, Lauren, Eads, Jennifer, Hope, Thomas A., Singh, Simron, Salem, Riad, Metz, David C., Naraev, Boris G., Reidy-Lagunes, Diane L., Howe, James R., Pommier, Rodney F., Menda, Yusuf, Chan, Jennifer A.

“…This article is the result of the North American Neuroendocrine Tumor Society consensus conference on the medical management of pancreatic neuroendocrine…”
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The impact of DNA testing on management of patients with colorectal cancer by Howe, James R.

“…Knowledge of the genetic basis of colorectal cancer has evolved over the past decades, allowing for the pre‐symptomatic identification of affected patients in…”
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PTEN Regulates Dendritic Arborization by Decreasing Microtubule Polymerization Rate by Getz, Stephanie A, Tariq, Kamran, Marchand, Dylan H, Dickson, Conor R, Howe Vi, James R, Skelton, Patrick D, Wang, Wei, Li, Meijie, Barry, Jeremy M, Hong, Jennifer, Luikart, Bryan W

“…Phosphatase and tensin homolog (PTEN) is a major negative regulator of the phosphatidylinositol-3-kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR)…”
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Translational Diagnostics and Therapeutics in Pancreatic Neuroendocrine Tumors by Maxwell, Jessica E, Sherman, Scott K, Howe, James R

“…Pancreatic neuroendocrine tumors (PNET) are rare tumors, but have been increasing in incidence. Although typically thought of as indolent, more than half of…”
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MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation by Howe, 6th, James R, Li, Emily S, Streeter, Sarah E, Rahme, Gilbert J, Chipumuro, Edmond, Russo, Grace B, Litzky, Julia F, Hills, L Benjamin, Rodgers, Kyla R, Skelton, Patrick D, Luikart, Bryan W

“…Neurogenesis is a highly-regulated process occurring in the dentate gyrus that has been linked to learning, memory, and antidepressant efficacy. MicroRNAs…”
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Prioritization of Fluorescence In Situ Hybridization (FISH) Probes for Differentiating Primary Sites of Neuroendocrine Tumors with Machine Learning by Pietan, Lucas, Vaughn, Hayley, Howe, James R, Bellizzi, Andrew M, Smith, Brian J, Darbro, Benjamin, Braun, Terry, Casavant, Thomas

“…Determining neuroendocrine tumor (NET) primary sites is pivotal for patient care as pancreatic NETs (pNETs) and small bowel NETs (sbNETs) have distinct…”
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Functional Copy-Number Alterations as Diagnostic and Prognostic Biomarkers in Neuroendocrine Tumors by Vaughn, Hayley, Major, Heather, Kadera, Evangeline, Keck, Kendall, Dunham, Timothy, Qian, Qining, Brown, Bartley, Scott, Aaron, Bellizzi, Andrew M, Braun, Terry, Breheny, Patrick, Quelle, Dawn E, Howe, James R, Darbro, Benjamin

“…Functional copy-number alterations (fCNAs) are DNA copy-number changes with concordant differential gene expression. These are less likely to be bystander…”
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Stargazin modulates AMPA receptor gating and trafficking by distinct domains by Tomita, Susumu, Sekiguchi, Masayuki, Wada, Keiji, Howe, James R, Adesnik, Hillel, Zhang, Wei, Nicoll, Roger A, Bredt, David S

“…AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors mediate fast excitatory synaptic transmission in the brain. These ion channels…”
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Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor by Straub, Christoph, Noam, Yoav, Nomura, Toshihiro, Yamasaki, Miwako, Yan, Dan, Fernandes, Herman B., Zhang, Ping, Howe, James R., Watanabe, Masahiko, Contractor, Anis, Tomita, Susumu

“…Synaptic communication between neurons requires the precise localization of neurotransmitter receptors to the correct synapse type. Kainate-type glutamate…”
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RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth by Umesalma, Shaikamjad, Kaemmer, Courtney A, Kohlmeyer, Jordan L, Letney, Blake, Schab, Angela M, Reilly, Jacqueline A, Sheehy, Ryan M, Hagen, Jussara, Tiwari, Nitija, Zhan, Fenghuang, Leidinger, Mariah R, O'Dorisio, Thomas M, Dillon, Joseph, Merrill, Ronald A, Meyerholz, David K, Perl, Abbey L, Brown, Bart J, Braun, Terry A, Scott, Aaron T, Ginader, Timothy, Taghiyev, Agshin F, Zamba, Gideon K, Howe, James R, Strack, Stefan, Bellizzi, Andrew M, Narla, Goutham, Darbro, Benjamin W, Quelle, Frederick W, Quelle, Dawn E

“…Hyperactivated AKT/mTOR signaling is a hallmark of pancreatic neuroendocrine tumors (PNETs). Drugs targeting this pathway are used clinically, but tumor…”
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Identification of primary tumors in patients presenting with metastatic gastroenteropancreatic neuroendocrine tumors by Keck, Kendall J., MD, Maxwell, Jessica E., MD, Menda, Yusuf, MD, Bellizzi, Andrew, MD, Dillon, Joseph, MD, O'Dorisio, Thomas M., MD, Howe, James R., MD

“…Background Patients with gastroenteropancreatic neuroendocrine tumors often present with metastases. Identification of the primary tumor is important for…”
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The mouse as a model for neuropsychiatric drug development by Howe, James R., Bear, Mark F., Golshani, Peyman, Klann, Eric, Lipton, Stuart A., Mucke, Lennart, Sahin, Mustafa, Silva, Alcino J.

“…Much has been written about the validity of mice as a preclinical model for brain disorders. Critics cite numerous examples of apparently effective treatments…”
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Hamartomatous Polyposis Syndromes by Calva, Daniel, MD, Howe, James R., MD

“…Since the histologic description of the hamartomatous polyp in 1957 by Horrilleno and colleagues, descriptions have appeared of several different syndromes…”
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Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function by Levy, Aaron D., Xiao, Xiao, Shaw, Juliana E., Sudarsana Devi, Suma Priya, Katrancha, Sara Marie, Bennett, Anton M., Greer, Charles A., Howe, James R., Machida, Kazuya, Koleske, Anthony J.

“…Hyperactivating mutations in the non-receptor tyrosine phosphatase SHP2 cause Noonan syndrome (NS). NS is associated with cognitive deficits, but how…”
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How AMPA Receptor Desensitization Depends on Receptor Occupancy by Robert, Antoine, Howe, James R

“…AMPA-type glutamate receptors mediate fast excitatory transmission at many central synapses, and rapid desensitization of these receptors can shape the decay…”
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Do giant parathyroid adenomas represent a distinct clinical entity? by Spanheimer, Philip M., MD, Stoltze, Andrew J., BA, Howe, James R., MD, Sugg, Sonia L., MD, Lal, Geeta, MD, Weigel, Ronald J., MD, PhD

“…Background The size of abnormal parathyroid glands in patients with primary hyperparathyroidism (PHPT) is highly variable, but the clinical significance of…”
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Liver-directed surgery of neuroendocrine metastases: What is the optimal strategy? by Maxwell, Jessica E., MD, MBA, Sherman, Scott K., MD, O'Dorisio, Thomas M., MD, Bellizzi, Andrew M., MD, Howe, James R., MD

“…Introduction Neuroendocrine tumors (NETs) frequently metastasize to the liver. Operative debulking offers symptomatic relief and improved survival; however,…”
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