Search Results - "HOWARD, P. C"

Impact of interleukin-1β antibody (canakinumab) on glycaemic indicators in patients with type 2 diabetes mellitus: Results of secondary endpoints from a randomized, placebo-controlled trial by Hensen, J, Howard, C.P, Walter, V, Thuren, T

“…Abstract Aims/hypothesis This study was conducted to determine the optimal monthly subcutaneous dose of canakinumab (a human monoclonal anti-human IL-1β…”
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Exploring the FDA Adverse Event Reporting System to Generate Hypotheses for Monitoring of Disease Characteristics by Fang, H, Su, Z, Wang, Y, Miller, A, Liu, Z, Howard, P C, Tong, W, Lin, S M

“…The US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) is a database for postmarketing drug safety monitoring and influences changes…”
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Complementarity and the use of indicator groups for reserve selection in Uganda by Balmford, Andrew, Howard, Peter C, Viskanic, Paolo, Davenport, Tim R. B, Kigenyi, Fred W, Baltzer, Michael, Dickinson, Chris J, Lwanga, Jeremiah S, Matthews, Roger A

“…A major obstacle to conserving tropical biodiversity is the lack of information as to where efforts should be concentrated. One potential solution is to focus…”
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Protected area planning in the tropics: Uganda's national system of forest nature reserves by Howard, P. C., Davenport, T. R. B., Kigenyi, F. W., Viskanic, P., Baltzer, M. C., Dickinson, C. J., Lwanga, J., Matthews, R. A., Mupada, E.

“…Uganda is one of the most biologically diverse countries in Africa, with much of its biodiversity represented in a system of 10 national parks, 10 wildlife…”
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Effect of anti-IL-1β antibody (canakinumab) on insulin secretion rates in impaired glucose tolerance or type 2 diabetes: results of a randomized, placebo-controlled trial by Rissanen, A., Howard, C. P., Botha, J., Thuren, T.

“…Aims Evaluate anti‐interleukin‐1β (IL‐1β) antibody, canakinumab, in patients with type 2 diabetes and impaired glucose tolerance (IGT) in whom hyperglycaemia…”
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Microbiological survey of commercial tattoo and permanent makeup inks available in the United States by Nho, S.W., Kim, S.‐J., Kweon, O., Howard, P.C., Moon, M.S., Sadrieh, N.K., Cerniglia, C.E.

“…Aims Tattooing and use of permanent makeup (PMU) has dramatically increased over the last decade, with a concomitant increase in ink‐related infections. The…”
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Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice by Howard, P C, Eppley, R M, Stack, M E, Warbritton, A, Voss, K A, Lorentzen, R J, Kovach, R M, Bucci, T J

“…Fumonisin B1 (FB1) is a mycotoxin isolated from Fusarium fungi that contaminate crops worldwide. A previous study demonstrated that FB1 promoted preneoplastic…”
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Levels of retinyl palmitate and retinol in the skin of SKH-1 mice topically treated with retinyl palmitate and concomitant exposure to simulated solar light for thirteen weeks by Yan, J, Xia, Q, Wamer, WG, Boudreau, MD, Warbritton, A, Howard, PC, Fu, PP

“…Retinyl esters account for more than 70% of the endogenous vitamin A found in human skin, and retinyl palmitate is one of the retinyl esters in this pool…”
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Renal effects of fumonisin mycotoxins in animals by Bucci, T J, Howard, P C, Tolleson, W H, Laborde, J B, Hansen, D K

“…Fumonisins are mycotoxins produced worldwide by Fusarium fungi, principally F. moniliforme. The fungus is present in virtually all harvested corn, but the…”
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Quantification of glycolic acid in cosmetic products using reversed phase high performance liquid chromatography by Couch, L. H., Howard, P. C.

“…Synopsis Many cosmetics contain keratolytic hydroxy acids to correct the effects of photoageing on human skin. Although methods exist for quantifying the…”
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Effects of fumonisin B1 in pregnant rats. Part 2 by COLLINS, T. F. X, SPRANDO, R. L, RUGGLES, D. I, OLEJNIK, N, RORIE, J. I, BLACK, T. N, SHACKELFORD, M. E, LABORDE, J. B, HANSEN, D. K, EPPLEY, R. M, TRUCKSESS, M. W, HOWARD, P. C, BRYANT, M. A

“…The developmental toxicity of purified fumonisin B1 (FB1), a mycotoxin from the common corn fungus Fusarium moniliforme, was examined in Charles River rats…”
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Effects of fumonisin B1 in pregnant rats by COLLINS, T. F. X, SHACKELFORD, M. E, RUGGLES, D. I, OLEJNIK, N, RORIE, J. I, SPRANDO, R. L, BLACK, T. N, LABORDE, J. B, HANSEN, D. K, EPPLEY, R. M, TRUCKSESS, M. W, HOWARD, P. C, BRYANT, M. A

“…Fumonisin B1 (FB1), the major mycotoxin from Fusarium moniliforme, has been implicated as a causative agent in several animal and human diseases. Despite…”
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Polycyclic aromatic hydrocarbons enhance terminal cell death of human ectocervical cells by Rorke, E A, Sizemore, N, Mukhtar, H, Couch, L H, Howard, P C

“…Polycyclic aromatic hydrocarbons (PAH) are a class of chemical carcinogens whose active metabolites form DNA adducts, resulting in specific mutational events…”
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Infrared imaging of subcutaneous veins by Zharov, Vladimir P., Ferguson, Scott, Eidt, John F., Howard, Paul C., Fink, Louis M., Waner, Milton

“…Background and Objectives Imaging of subcutaneous veins is important in many applications, such as gaining venous access and vascular surgery. Despite a long…”
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Role of nitroreductases but not cytochromes P450 in the metabolic activation of 1-nitropyrene in the HepG2 human hepatoblastoma cell line by Silvers, Kimberly J, Couch, Letha H, Rorke, Ellen A, Howard, Paul C

“…1-Nitropyrene is an environmental contaminant that is mutagenic in many prokaryotic and eukaryotic systems, including the hypoxanthine-guanosine phosphoribosyl…”
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Response of mouse skin to tattooing: use of SKH-1 mice as a surrogate model for human tattooing by Gopee, Neera V., Cui, Yanyan, Olson, Greg, Warbritton, Alan R., Miller, Barbara J., Couch, Letha H., Wamer, Wayne G., Howard, Paul C.

“…Tattooing is a popular cosmetic practice involving more than 45 million US citizens. Since the toxicology of tattoo inks and pigments used to formulate tattoo…”
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Photoreaction, Phototoxicity, and Photocarcinogenicity of Retinoids by Fu, P. P., Cheng, S.-H., Coop, L., Xia, Q., Culp, S. J., Tolleson, W. H., Wamer, W. G., Howard, P. C.

“…Sunlight is a human carcinogen. Many retinoid-containing cosmetics are used to protect damages caused by sunlight irradiation. Since retinol is thermally…”
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The kinetics of 1-nitropyrene and 3-nitrofluoranthene metabolism using bovine liver xanthine oxidase by Bauer, S L, Howard, P C

“…The cytosolic molybdoflavoprotein xanthine oxidase has been shown to catalyze the reduction of exocyclic nitro groups to the corresponding nitroso,…”
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Kinetics and cofactor requirements for the nitroreductive metabolism of 1-nitropyrene and 3-nitrofluoranthene by rabbit liver aldehyde oxidase by Bauer, S L, Howard, P C

“…Nitrated polycyclic aromatic hydrocarbons are environmental pollutants that have been shown to arise from a variety of sources, including diesel exhaust…”
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Differential response of normal and HPV immortalized ectocervical epithelial cells to B[a]P by Sizemore, N, Mukhtar, H, Couch, L H, Howard, P C, Rorke, E A

“…Cigarette smoking has been established as a risk factor for the development of cervical cancer. Polycyclic aromatic hydrocarbons such as benzo[a]pyrene…”
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