Search Results - "HOTA, PRASANTA K"

NMR Structure of a Heterodimeric SAM:SAM Complex: Characterization and Manipulation of EphA2 Binding Reveal New Cellular Functions of SHIP2 by Lee, Hyeong J., Hota, Prasanta K., Chugha, Preeti, Guo, Hong, Miao, Hui, Zhang, Liqun, Kim, Soon-Jeung, Stetzik, Lukas, Wang, Bing-Cheng, Buck, Matthias

“…The sterile alpha motif (SAM) for protein-protein interactions is encountered in over 200 proteins, but the structural basis for its interactions is just…”
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Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain by Tong, Yufeng, Chugha, Preeti, Hota, Prasanta K., Alviani, Rebecca S., Li, Mei, Tempel, Wolfram, Shen, Limin, Park, Hee-Won, Buck, Matthias

“…Plexins are the first known transmembrane receptors that interact directly with small GTPases. On binding to certain Rho family GTPases, the receptor regulates…”
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Structure and Function of the Intracellular Region of the Plexin-B1 Transmembrane Receptor by Tong, Yufeng, Hota, Prasanta K., Penachioni, Junia Y., Hamaneh, Mehdi B., Kim, SoonJeung, Alviani, Rebecca S., Shen, Limin, He, Hao, Tempel, Wolfram, Tamagnone, Luca, Park, Hee-Won, Buck, Matthias

“…Members of the plexin family are unique transmembrane receptors in that they interact directly with Rho family small GTPases; moreover, they contain a…”
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Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions by Hota, Prasanta K., Buck, Matthias

“…Plexin transmembrane receptors and their semaphorin ligands, as well as their co-receptors (Neuropilin, Integrin, VEGFR2, ErbB2, and Met kinase) are emerging…”
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Structural Basis of Rnd1 Binding to Plexin Rho GTPase Binding Domains (RBDs) by Wang, Hui, Hota, Prasanta K., Tong, Yufeng, Li, Buren, Shen, Limin, Nedyalkova, Lyudmila, Borthakur, Susmita, Kim, SoonJeung, Tempel, Wolfram, Buck, Matthias, Park, Hee-Won

“…Plexin receptors regulate cell adhesion, migration, and guidance. The Rho GTPase binding domain (RBD) of plexin-A1 and -B1 can bind GTPases, including Rnd1. By…”
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Thermodynamic characterization of two homologous protein complexes: Associations of the semaphorin receptor plexin‐B1 RhoGTPase binding domain with Rnd1 and active Rac1 by Hota, Prasanta K., Buck, Matthias

“…Plexin receptors function in response to semaphorin guidance cues in a variety of developmental processes involving cell motility. Interactions with Rho, as…”
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Characterizing Plexin GTPase Interactions Using Gel Filtration, Surface Plasmon Resonance Spectrometry, and Isothermal Titration Calorimetry by Muller-Greven, Jeannine, Kim, SoonJeung, Hota, Prasanta K, Tong, Yufeng, Borthakur, Susmita, Buck, Matthias

“…Plexins are unique, as they are the first example of a transmembrane receptor that interacts directly with small GTPases, a family of proteins that are…”
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Synthesis of Novel Diaziridinyl Quinone Isoxazole Hybrids and Evaluation of Their Anti-Cancer Activity as Potential Tubulin-Targeting Agents by Kumar, P Ravi, Yennam, Satyanarayana, Raghavulu, K, Velatooru, Loka Reddy, Kotla, Siva Reddy, Penugurti, Vasudevarao, Hota, Prasanta K, Behera, Manoranjan, Shree, A Jaya

“…Two series of diaziridinyl quinone isoxazole derivatives were prepared and evaluated for their cytotoxic activity against MCF7, HeLa, BT549, A549 and HEK293…”
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Insights into Oncogenic Mutations of Plexin-B1 Based on the Solution Structure of the Rho GTPase Binding Domain by Tong, Yufeng, Hota, Prasanta K., Hamaneh, Mehdi Bagheri, Buck, Matthias

“…The plexin family of transmembrane receptors are important for axon guidance, angiogenesis, but also in cancer. Recently, plexin-B1 somatic missense mutations…”
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An efficient synthesis of 8-substituted Odoratine derivatives by the Suzuki coupling reaction by KUMAR, P RAVI, BALAKRISHNA, C, MURALI, B, GUDIPATI, RAMAKRISHNA, HOTA, PRASANTA K, CHAUDHARY, AVINASH B, SHREE, A JAYA, YENNAM, SATYANARAYANA, BEHERA, MANORANJAN

“…An efficient method for the preparation of 8-substituted odoratine [(3-(3 ′ , 4 ′ -methylenedioxyphenyl)-5,6,7-trimethoxyisoflavone] derivatives, structurally…”
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Development of Bacteriorhodopsin Analogues and Studies of Charge Separated Excited States in the Photoprocesses of Linear Polyenes by Singh, Anil K., Hota, Prasanta K.

“…Development of bacteriorhodopsin (bR) analogues employing chromophore substitution technique for the purpose of characterizing the binding site of bR and…”
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Ethenyl indoles as neutral hydrophobic fluorescence probes by Singh, Anil K., Hota, Prasanta K.

“…3‐(4‐Nitrophenylethenyl‐E)‐NH‐indole (1), 3‐(4‐nitrophenyl ethenyl‐E)‐N‐acetylindole (2), and 3‐(4‐nitrophenylethenyl‐E)‐N‐benzenesulfonylindole (3) are…”
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Absorption and fluorescence spectral properties of donor-acceptor ethenes bearing indole and p-nitrophenyl substituents by Singh, Anil K, Hota, Prasanta K

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Biochemical and mutational analysis of intracellular regions of the Plexin‐B1 guidance receptor as a R‐RasGAP by Kim, SoonJeung, Hota, Prasanta K, Buck, Matthias

“…Plexins are single transmembrane receptors for semaphorin guidance cues, which regulate the cell motility through changes in the cells actin cytoskeleton…”
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Dynamic Protein-Protein Complexes: How Alternative Interactions Create Ensembles and How Solution NMR and MD Simulations can Characterize them by Buck, Matthias, Zhang, Liqun, Lee, Hyeong J., Hota, Prasanta K.

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Studies on the Structure and Function of the Intracellular Region of the Plexin-B1 Transmembrane Receptor by Hota, Prasanta K., Tong, Yufeng, Penachioni, Junia Y., Tamagnone, Luca, Park, Hee-Won, Buck, Matthias

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NMR Structure of a Heterodimeric SAM: SAM Complex: Characterization and Manipulation of Eph by Lee, Hyeong J, Hota, Prasanta K, Chugha, Preeti, Guo, Hong, Miao, Hui, Zhang, Liqun, Kim, Soon-Jeung, Stetzik, Lukas, Wang, Bing-Cheng, Buck, Matthias, Ferris, Hedda U, Dunin-Horkawicz, Stanislaw, Hornig, Nora, Hulko, Michael, Martin, Jorg, Schultz, Joachim E, Zeth, Kornelius, Lupas, Andrei N, Coles, Murray

“…The sterile alpha motif (SAM) for protein-protein interactions is encountered in over 200 proteins, but the structural basis for its interactions is just…”
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Fluorescence and photoisomerization studies of p-nitrophenyl-substituted ethenylindoles by Singh, Anil K., Hota, Prasanta K.

“…The synthesis, electronic absorption, fluorescence (λf, λex, Φf, τf) and photoisomerization (Φt→c, photostationary state composition) properties of…”
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Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector DomainS by Tong, Yufeng, Chugha, Preeti, Hota, Prasanta K., Alviani, Rebecca S., Li, Mei, Tempel, Wolfram, Shen, Limin, Park, Hee-Won, Buck, Matthias

“…Plexins are the first known transmembrane receptors that interact directly with small GTPases. On binding to certain Rho family GTPases, the receptor regulates…”
Get full text