Search Results - "HOSONO, Takashi"
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Macrophage potentiates the recovery of liver zonation and metabolic function after acute liver injury
Published in Scientific reports (06-05-2021)“…The liver is an exclusive organ with tremendous regenerative capacity. Liver metabolic functions exhibit spatial heterogeneity, reflecting liver zonation. The…”
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Apolipoprotein E Regulates the Integrity of Tight Junctions in an Isoform-dependent Manner in an in Vitro Blood-Brain Barrier Model
Published in The Journal of biological chemistry (20-05-2011)“…Apolipoprotein E (apoE) is a major apolipoprotein in the brain. The ϵ4 allele of apoE is a major risk factor for Alzheimer disease, and apoE deficiency in mice…”
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3
Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis
Published in Cell metabolism (09-01-2018)“…Adipose tissue fibrosis is a hallmark of malfunction that is linked to insulin resistance and type 2 diabetes; however, what regulates this process remains…”
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Light is an Important Limiting Factor for the Vertical Distribution of the Largest Extant Benthic Foraminifer Cycloclypeus carpenteri
Published in Journal of earth science (Wuhan, China) (01-12-2022)“…Cycloclypeus carpenteri is the largest extant benthic foraminifer, dwelling in the deep euphotic zone (a water depth between 60 and 130 m) of the warm…”
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5
A novel third mesh-like myometrial layer connects the longitudinal and circular muscle fibers -A potential stratum to coordinate uterine contractions
Published in Scientific reports (19-05-2020)“…Periodic myometrial contraction is one of the important uterine functions to achieve embryo implantation and parturition. Although it is well-known that the…”
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Cinnamon extract improves abnormalities in glucose tolerance by decreasing Acyl-CoA synthetase long-chain family 1 expression in adipocytes
Published in Scientific reports (22-07-2022)“…We previously demonstrated that cinnamon extract (CE) alleviates streptozotocin-induced type 1 diabetes in rats. The present study aimed to elucidate the…”
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7
New diagnostic criteria and operative strategy for cesarean scar syndrome: Endoscopic repair for secondary infertility caused by cesarean scar defect
Published in The journal of obstetrics and gynaecology research (01-09-2015)“…Aim The aim of the present study was to assess the efficacy of endoscopic repair for secondary infertility caused by post‐cesarean scar defect (PCSD). Our…”
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Diallyl Trisulfide Inhibits Platelet Aggregation through the Modification of Sulfhydryl Groups
Published in Journal of agricultural and food chemistry (12-02-2020)“…Diallyl trisulfide (DATS) is a secondary metabolite of allicin, a volatile organosulfur flavoring compound generated by the crushing of garlic. These compounds…”
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Cinnamon extract enhances glucose uptake in 3T3-L1 adipocytes and C2C12 myocytes by inducing LKB1-AMP-activated protein kinase signaling
Published in PloS one (14-02-2014)“…We previously demonstrated that cinnamon extract (CE) ameliorates type 1 diabetes induced by streptozotocin in rats through the up-regulation of glucose…”
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Oxygen metabolic responses of three species of large benthic foraminifers with algal symbionts to temperature stress
Published in PloS one (03-03-2014)“…Water temperature affects the physiology of large benthic foraminifers (LBFs) with algal symbionts dwelling in coral reef environments. However, the detailed…”
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Diallyl Trisulfide Prevents Obesity and Decreases miRNA‐335 Expression in Adipose Tissue in a Diet‐Induced Obesity Rat Model
Published in Molecular nutrition & food research (01-07-2021)“…Scope Diallyl trisulfide (DATS), an organosulfur compound generates in crushed garlic, has various beneficial health effects. A growing body of evidence…”
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12
The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship
Published in International journal of molecular sciences (12-01-2023)“…The circadian rhythm, which is necessary for reproduction, is controlled by clock genes. In the mouse uterus, the oscillation of the circadian clock gene has…”
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Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure
Published in Cell metabolism (01-12-2015)“…Catecholamines promote lipolysis both in brown and white adipocytes, whereas the same stimuli preferentially activate thermogenesis in brown adipocytes…”
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Two oxytocin analogs, N-(p-fluorobenzyl) glycine and N-(3-hydroxypropyl) glycine, induce uterine contractions ex vivo in ways that differ from that of oxytocin
Published in PloS one (09-02-2023)“…Contraction of the uterus is critical for parturient processes. Insufficient uterine tone, resulting in atony, can potentiate postpartum hemorrhage; thus, it…”
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15
The role of increased FGF21 in VLDL-TAG secretion and thermogenic gene expression in mice under protein malnutrition
Published in Bioscience, biotechnology, and biochemistry (24-04-2021)“…Protein malnutrition promotes hepatic lipid accumulation in growing animals. In these animals, fibroblast growth factor 21 (FGF21) rapidly increases in the…”
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Uterine Deletion of Bmal1 Impairs Placental Vascularization and Induces Intrauterine Fetal Death in Mice
Published in International journal of molecular sciences (11-07-2022)“…Recently, it was demonstrated that the expression of was decreased in the endometrium of women suffering from recurrent spontaneous abortion. To investigate…”
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Prevention of Cardiovascular Diseases by Garlic-Derived Sulfur Compounds
Published in Journal of Nutritional Science and Vitaminology (2015)“…Lifestyle-related diseases have complex pathogenesis which consists of several different steps. Basic causes of the diseases are attributed to unhealthy…”
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The garlic-derived organosulfur compound diallyl trisulphide suppresses tissue factor function
Published in Food & function (07-02-2022)“…Tissue factor (TF) is a critical initiator of extrinsic coagulation that sometimes causes thromboembolism. Diallyl trisulphide (DATS) is a secondary metabolite…”
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Verification of the Antidiabetic Effects of Cinnamon (Cinnamomum zeylanicum) Using Insulin-Uncontrolled Type 1 Diabetic Rats and Cultured Adipocytes
Published in Bioscience, biotechnology, and biochemistry (2010)“…It has long been believed that an intake of cinnamon (Cinnamomum zeylanicum) alleviates diabetic pathological conditions. However, it is still controversial…”
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Shell productivity of the large benthic foraminifer Baculogypsina sphaerulata, based on the population dynamics in a tropical reef environment
Published in Coral reefs (01-03-2016)“…Carbonate production by large benthic foraminifers is sometimes comparable to that of corals and coralline algae, and contributes to sedimentation on reef…”
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