Search Results - "HOSMANE, SUNEIL"

Curcumin protects axons from degeneration in the setting of local neuroinflammation by Tegenge, Million Adane, Rajbhandari, Labchan, Shrestha, Shiva, Mithal, Aditya, Hosmane, Suneil, Venkatesan, Arun

“…Axon degeneration is a hallmark of several central nervous system (CNS) disorders, including multiple sclerosis (MS), Alzheimer's disease (AD) and Parkinson's…”
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Toll-like receptor 4 deficiency impairs microglial phagocytosis of degenerating axons by Rajbhandari, Labchan, Tegenge, Million Adane, Shrestha, Shiva, Ganesh Kumar, Nishant, Malik, Adeel, Mithal, Aditya, Hosmane, Suneil, Venkatesan, Arun

“…Microglia are rapidly activated in the central nervous system (CNS) in response to a variety of injuries, including inflammation, trauma, and stroke. In…”
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Circular compartmentalized microfluidic platform: Study of axon-glia interactions by Hosmane, Suneil, Yang, In Hong, Ruffin, April, Thakor, Nitish, Venkatesan, Arun

“…We describe a compartmentalized circular microfluidic platform that enables directed cell placement within defined microenvironments for the study of axon-glia…”
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Toll/interleukin-1 receptor domain-containing adapter inducing interferon-β mediates microglial phagocytosis of degenerating axons by Hosmane, Suneil, Tegenge, Million Adane, Rajbhandari, Labchan, Uapinyoying, Prech, Ganesh Kumar, Nishant, Thakor, Nitish, Venkatesan, Arun

“…Following CNS injury, microglial phagocytosis of damaged endogenous tissue is thought to play an important role in recovery and regeneration. Previous work has…”
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1174-P: Application of NIS4 Technology for Stand-Alone and Sequential Identification of At-Risk NASH or Advanced Fibrosis in Nondiabetic, Prediabetic, and Type 2 Diabetic Patients by ROSENQUIST, CHRISTIAN, HAJJI, YACINE, MAGNANENSI, JÉRÉMY, STANKOVIC-VALENTIN, NICOLAS, HOSMANE, SUNEIL, SANYAL, ARUN J.

“…Background: Type 2 diabetes (T2D) is an independent risk factor for the development of nonalcoholic steatohepatitis (NASH. However, there is a need for…”
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A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study by Harrison, Stephen A, Ratziu, Vlad, Boursier, Jérôme, Francque, Sven, Bedossa, Pierre, Majd, Zouher, Cordonnier, Geneviève, Sudrik, Fouad Ben, Darteil, Raphael, Liebe, Roman, Magnanensi, Jérémy, Hajji, Yacine, Brozek, John, Roudot, Alice, Staels, Bart, Hum, Dean W, Megnien, Sophie Jeannin, Hosmane, Suneil, Dam, Noémie, Chaumat, Pierre, Hanf, Rémy, Anstee, Quentin M, Sanyal, Arun J

“…Non-invasive tests that can identify patients with non-alcoholic steatohepatitis (NASH) at higher risk of disease progression are lacking. We report the…”
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Compartmentalized microfluidic culture platform to study mechanism of paclitaxel-induced axonal degeneration by Yang, In Hong, Siddique, Rezina, Hosmane, Suneil, Thakor, Nitish, Höke, Ahmet

“…Chemotherapy induced peripheral neuropathy is a common and dose-limiting side effect of anticancer drugs. Studies aimed at understanding the underlying…”
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Valve-based microfluidic compression platform: single axon injury and regrowth by Hosmane, Suneil, Fournier, Adam, Wright, Rika, Rajbhandari, Labchan, Siddique, Rezina, Yang, In Hong, Ramesh, K T, Venkatesan, Arun, Thakor, Nitish

“…We describe a novel valve-based microfluidic axon injury micro-compression (AIM) platform that enables focal and graded compression of micron-scale segments of…”
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Chemistry of C-Trimethylsilyl-Substituted Heterocarboranes. 28. Selective Alkylation and Reactivity of “Carbons Adjacent” and “Carbons Apart” Tetracarba-nido-dodecaborane(12) Derivatives toward Group 1 and Group 2 Metals. Synthetic, Spectroscopic, and Structural Investigations on Lithium-, Sodium-, Potassium-, Cesium-, and Magnesium-Complexed C4B8 Carboranes by Hosmane, Narayan S, Zhang, Hongming, Maguire, John A, Wang, Ying, Demissie, Temesgen, Colacot, Thomas J, Ezhova, Maria B, Lu, Kai-Juan, Zhu, Dunming, Gray, Thomas G, Helfert, Sarah C, Hosmane, Suneil N, Collins, Jess D, Baumann, Frank, Kaim, Wolfgang, Lipscomb, William N

“…The “carbons apart” tetracarbon carborane nido-2,6-(R)2-4,12-(SiMe3)2-2,4,6,12-C4B8H8 (R = SiMe3 (I), n-butyl (II)) and several of its B-alkylated derivatives…”
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Serum levels of miR-34a to rule-out NAFLD in healthy subjects and identify NAFLD patients with active NASH (NAS>= 4) and significant liver fibrosis (F >= 2) by Harrison, Stephen, Anstee, Quentin, Ratziu, Vlad, Bedossa, Pierre, Cordonnier, Genevieve, Majd, Zouher, Roudot, Alice, Sudrick, Fouad Ben, Dam, Noémie, Brozek, John, Birman, Pascal, Chaumat, Pierre, Staels, Bart, Hum, Dean, Hosmane, Suneil, Hanf, Remy, Sanyal, Arun

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AS102 - Serum levels of miR-34a to rule-out NAFLD in healthy subjects and identify NAFLD patients with active NASH (NAS>= 4) and significant liver fibrosis (F >= 2) by Harrison, Stephen, Anstee, Quentin, Ratziu, Vlad, Bedossa, Pierre, Cordonnier, Genevieve, Majd, Zouher, Roudot, Alice, Sudrick, Fouad Ben, Dam, Noémie, Brozek, John, Birman, Pascal, Chaumat, Pierre, Staels, Bart, Hum, Dean, Hosmane, Suneil, Hanf, Remy, Sanyal, Arun

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279-LB: NIS4, a Novel Blood Test, Can Identify "At-Risk" NASH (NAS>4 and Fibrosis>2) in T2D Patients by STAELS, BART, RATZIU, VLAD, FRANCQUE, SVEN, HARRISON, STEPHEN A., BEDOSSA, PIERRE, ROUDOT, ALICE, MAJD, ZOUHER, BROZEK, JOHN, BEN-SUDRIK, FOUAD, BIRMAN, PASCAL, HUM, DEAN W., HOSMANE, SUNEIL, CHAUMAT, PIERRE, HANF, RéMY, CARIOU, BERTRAND, SANYAL, ARUN

“…Background and Aim: T2D is an independent risk factor for the development of nonalcoholic steatohepatitis (NASH). Amongst NASH patients, those with elevated…”
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SAT-299-Assessment of NIS4 clinical utility for identification of patients with active NASH (NAS ≥ 4) and significant fibrosis (F ≥ 2) in patients at risk of NASH by Hanf, Remy, Chaumat, Pierre, Majd, Zouher, Cordonnier, Genevieve, Brozek, John, Praca, Emilie, Sudrik, Fouad Ben, Bedossa, Prof. Pierre, Anstee, Prof. Quentin M., Francque, Prof. Sven, Harrison, Prof. Stephen A., Ratziu, Prof. Vlad, Mégnien, Sophie, Roudot, Alice, Hosmane, Suneil, Hum, Dean W., Sanyal, Arun J.

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Chemistry of C-Trimethylsilyl-Substituted Heterocarboranes. 26. Further Investigation of Oxidative Cage Closure, Cage Fusion, and Cage Isomerizations:  Synthetic, Structural, and Bonding Studies on “Carbons Adjacent” and “Carbons Apart” Tetracarba-nido-dodecaborane(12) Derivatives by Hosmane, Narayan S, Colacot, Thomas J, Zhang, Hongming, Yang, Jimin, Maguire, John A, Wang, Ying, Ezhova, Maria B, Franken, Andreas, Demissie, Temesgen, Lu, Kai-Juan, Zhu, Dunming, Thomas, Julie L. C, Collins, Jess D, Gray, Thomas G, Hosmane, Suneil N, Lipscomb, William N

“…A number of tetracarbon carboranes of the general form (SiMe3)2(R)2C4B8H8 (R = SiMe3 (III and IV) Me (XIII and XIV), n-Bu (VII, XI, and XII), t-Bu (VIII)) were…”
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Chemistry of C-Trimethylsilyl-Substituted Heterocarboranes. 27. Synthetic, Spectroscopic, Structural, and Reactivity Studies on d0 Hafnacarboranes of 2,3-C2B4-Carborane Ligands by Hosmane, Narayan S, Zhang, Hongming, Jia, Lei, Colacot, Thomas J, Maguire, John A, Wang, Xiaodong, Hosmane, Suneil N, Brooks, Karen A

“…The sodium/lithium compounds closo-exo-Li(THF)-1-Na(THF)-2-(SiMe3)-3-(R)-2,3-C2B4H4 (R = SiMe3, Me, H), were found to react with several different hafnium…”
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Innovative technologies to study mechanisms of CNS axonal degeneration by Hosmane, Suneil Narayan

“…Central nervous system (CNS) axons often span substantial distances and are situated in compositionally distinct microenvironments as compared to their cell…”
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Chemistry of C- Trimethylsilyl-Substituted Heterocarboranes. 27. Synthetic, Spectroscopic, Structural, and Reactivity Studies on d 0 Hafnacarboranes of 2,3-C 2 B 4 -Carborane Ligands by Hosmane, Narayan S., Zhang, Hongming, Jia, Lei, Colacot, Thomas J., Maguire, John A., Wang, Xiaodong, Hosmane, Suneil N., Brooks, Karen A.

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METALLABORANES AND METALLACARBORANES OF s-BLOCK ELEMENTS by Rana, Geeta, Maguire, John A., Hosmane, Suneil N., Hosmane, Narayan S.

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Chemistry of C- Trimethylsilyl-Substituted Heterocarboranes. 28. Selective Alkylation and Reactivity of “Carbons Adjacent” and “Carbons Apart” Tetracarba- nido -dodecaborane(12) Derivatives toward Group 1 and Group 2 Metals. Synthetic, Spectroscopic, and Structural Investigations on Lithium-, Sodium-, Potassium-, Cesium-, and Magnesium-Complexed C 4 B 8 Carboranes by Hosmane, Narayan S., Zhang, Hongming, Maguire, John A., Wang, Ying, Demissie, Temesgen, Colacot, Thomas J., Ezhova, Maria B., Lu, Kai-Juan, Zhu, Dunming, Gray, Thomas G., Helfert, Sarah C., Hosmane, Suneil N., Collins, Jess D., Baumann, Frank, Kaim, Wolfgang, Lipscomb, William N.

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