Search Results - "HOSKING, Martin"

A Systematic Review of Infective Endocarditis in Patients With Bovine Jugular Vein Valves Compared With Other Valve Types by Sharma, Ashutosh, Cote, Anita T., Hosking, Martin C.K., Harris, Kevin C.

“…The aim of this study was to systematically evaluate the incidence of infective endocarditis (IE) in right ventricle–to–pulmonary artery conduits and valves,…”
Get full text

Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut by Liu, Janet Z., Jellbauer, Stefan, Poe, Adam J., Ton, Vivian, Pesciaroli, Michele, Kehl-Fie, Thomas E., Restrepo, Nicole A., Hosking, Martin P., Edwards, Robert A., Battistoni, Andrea, Pasquali, Paolo, Lane, Thomas E., Chazin, Walter J., Vogl, Thomas, Roth, Johannes, Skaar, Eric P., Raffatellu, Manuela

“…Neutrophils are innate immune cells that counter pathogens by many mechanisms, including release of antimicrobial proteins such as calprotectin to inhibit…”
Get full text

Optical Coherence Tomography for the Early Detection of Coronary Vascular Changes in Children and Adolescents After Cardiac Transplantation: Findings From the International Pediatric OCT Registry by McGovern, Eimear, Hosking, Martin C K, Balbacid, Enrique, Voss, Christine, Berger, Felix, Schubert, Stephan, Harris, Kevin C

“…This study sought to describe the initial findings from the International Pediatric Optical Coherence Tomography (OCT) registry in pediatric heart transplant…”
Get full text

The role of chemokines during viral infection of the CNS by Hosking, Martin P, Lane, Thomas E

“…  Rather, JHMV viral proteins influence chemokine secretion through as yet undefined mechanisms [11], while the HIV-1 protein Nef influences neuronal chemokine…”
Get full text

Patterns of Early Coronary Artery Changes in Pediatric Heart Transplant Recipients Detected Using Optical Coherence Tomography by Laguë, Sabine L., Bone, Jeffrey N., Samuel, Rosh, Voss, Christine, Balbacid, Enrique, Hosking, Martin C.K., Schubert, Stephan, Harris, Kevin C.

“…Cardiac allograft vasculopathy, the leading cause of graft failure in pediatric heart transplant recipients, is characterized by diffuse and concentric…”
Get full text

G-CSF–mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands by Köhler, Anja, De Filippo, Katia, Hasenberg, Mike, van den Brandt, Cindy, Nye, Emma, Hosking, Martin P., Lane, Thomas E., Männ, Linda, Ransohoff, Richard M., Hauser, Anja E., Winter, Oliver, Schraven, Burkhart, Geiger, Hartmut, Hogg, Nancy, Gunzer, Matthias

“…Emergency mobilization of neutrophil granulocytes (neutrophils) from the bone marrow (BM) is a key event of early cellular immunity. The hematopoietic cytokine…”
Get full text

Outcomes of Radiofrequency Perforation for Pulmonary Atresia and Intact Ventricular Septum: A Single-Centre Experience by Rathgeber, Steven, Auld, Benjamin, Duncombe, Stephanie, Hosking, Martin C. K., Harris, Kevin C.

“…Percutaneous radiofrequency perforation (RFP) of the pulmonary valve is used as a primary therapy in neonates with pulmonary atresia and intact ventricular…”
Get full text

CXCR2 signaling protects oligodendrocytes and restricts demyelination in a mouse model of viral-induced demyelination by Hosking, Martin P, Tirotta, Emanuele, Ransohoff, Richard M, Lane, Thomas E

“…The functional role of ELR-positive CXC chemokines during viral-induced demyelination was assessed. Inoculation of the neuroattenuated JHM strain of mouse…”
Get full text

Physiological Responses to Exercise in Pediatric Heart Transplant Recipients by BOVARD, JOSHUA M, DE SOUZA, ASTRID M, HARRIS, KEVIN C, HUMAN, DEREK G, HOSKING, MARTIN C K, POTTS, JAMES E, ARMSTRONG, KATHRYN, SANDOR, GEORGE G S, COTE, ANITA T

“…INTRODUCTIONPediatric heart transplant (HTx) recipients have reduced exercise capacity typically two-thirds of predicted values, the mechanisms of which are…”
Get full text

Type I IFN Signaling Is Dispensable during Secondary Viral Infection by Hosking, Martin P, Flynn, Claudia T, Whitton, J Lindsay

“…Innate immune responses in general, and type I interferons (T1IFNs) in particular, play an important and often essential role during primary viral infections,…”
Get full text

A protective role for ELR+ chemokines during acute viral encephalomyelitis by Hosking, Martin P, Liu, Liping, Ransohoff, Richard M, Lane, Thomas E

“…The functional role of ELR-positive CXC chemokines in host defense during acute viral-induced encephalomyelitis was determined. Inoculation of the neurotropic…”
Get full text

Antigen-specific naive CD8+ T cells produce a single pulse of IFN-γ in vivo within hours of infection, but without antiviral effect by Hosking, Martin P, Flynn, Claudia T, Whitton, J Lindsay

“…In vitro studies have shown that naive CD8(+) T cells are unable to express most of their effector proteins until after at least one round of cell division has…”
Get full text

Feasibility of optical coherence tomography in children with Kawasaki disease and pediatric heart transplant recipients by Harris, Kevin C, Manouzi, Anas, Fung, Anthony Y, De Souza, Astrid, Bezerra, Hiram G, Potts, James E, Hosking, Martin C K

“…Optical coherence tomography (OCT) is a high-resolution intravascular imaging technique used in adults. We tested the hypothesis that OCT could identify…”
Get full text

iPSC-derived NK cells expressing high-affinity IgG Fc receptor fusion CD64/16A to mediate flexible, multi-tumor antigen targeting for lymphoma by Dixon, Kate J, Snyder, Kristin M, Khaw, Melissa, Hullsiek, Robert, Davis, Zachary B, Matson, Anders W, Shirinbak, Soheila, Hancock, Bryan, Bjordahl, Ryan, Hosking, Martin, Miller, Jeffrey S, Valamehr, Bahram, Wu, Jianming, Walcheck, Bruce

“…NK cells can mediate tumor cell killing by natural cytotoxicity and by antibody-dependent cell-mediated cytotoxicity (ADCC), an anti-tumor mechanism mediated…”
Get full text

The pathogenesis of murine coronavirus infection of the central nervous system by Lane, Thomas E, Hosking, Martin P

“…Mouse hepatitis virus (MHV) is a positive-strand RNA virus that causes an acute encephalomyelitis that later resolves into a chronic fulminating demyelinating…”
Get full text

TCR independent suppression of CD8+ T cell cytokine production mediated by IFNγ in vivo by Hosking, Martin P, Flynn, Claudia T, Whitton, J. Lindsay

“…Abstract CD8+ memory T cells produce IFNγ within hours of secondary infection, but this is quickly terminated in vivo despite the presence of stimulatory viral…”
Get full text

Intimal thickening at coronary bifurcations in pediatric heart transplant recipients by Duncombe, Stephanie L., Hosking, Martin C. K., Coté, Anita T., Voss, Christine, Harris, Kevin C.

“…Heart transplant recipients are at increased risk for atherosclerosis and cardiac allograft vasculopathy, both initially presenting as intimal thickening. We…”
Get full text

A Canadian, retrospective, multicenter experience with selexipag for a heterogeneous group of pediatric pulmonary hypertension patients by Youssef, David, Richards, Susan, Lague, Sabine, Sheppard, Catherine, Smith, Jenna, Vorhies, Erika, Hosking, Martin, Pietrosanu, Matthew, Bates, Angela

“…Selexipag, an oral nonprostanoid prostaglandin receptor agonist, has led to reduced morbidity and mortality in adults with pulmonary arterial hypertension…”
Get full text

CD8+ memory T cells appear exhausted within hours of acute virus infection by Hosking, Martin P, Flynn, Claudia T, Botten, Jason, Whitton, J Lindsay

“…CD8(+) memory T cells are abundant and are activated in a near-synchronous manner by infection, thereby providing a unique opportunity to evaluate the…”
Get full text

iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting by Snyder, Kristin M, Dixon, Kate J, Davis, Zachary, Hosking, Martin, Hart, Geoffrey, Khaw, Melissa, Matson, Anders, Bjordahl, Ryan, Hancock, Bryan, Shirinbak, Soheila, Miller, Jeffrey S, Valamehr, Bahram, Wu, Jianming, Walcheck, Bruce

“…BackgroundAntibody therapies can direct natural killer (NK) cells to tumor cells, tumor-associated cells, and suppressive immune cells to mediate…”
Get full text