Search Results - "HORWITZ, A. H"

Competition between rBPI23, a recombinant fragment of bactericidal/permeability-increasing protein, and lipopolysaccharide (LPS)-binding protein for binding to LPS and gram-negative bacteria by GAZZANO-SANTORO, H, MESZAROS, K, BIRR, C, CARROLL, S. F, THEOFAN, G, HORWITZ, A. H, ED LIM, ABERLE, S, KASLER, H, PARENT, J. B

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Escherichia coli Secretion of an Active Chimeric Antibody Fragment by Better, Marc, Chang, C. Paul, Robinson, Randy R., Horwitz, Arnold H.

“…A chimeric mouse-human Fab protein that binds specifically to the human carcinoma cell line C3347 has been expressed and secreted from Escherichia coli. This…”
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Secretion of Functional Antibody and Fab Fragment from Yeast Cells by Horwitz, Arnold H., Chang, C. Paul, Better, Marc, Hellstrom, Karl Erik, Robinson, Randy R.

“…We have constructed yeast strains that secrete functional mouse--human chimeric antibody and its Fab fragment into the culture medium. For chimeric whole…”
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Human lipopolysaccharide-binding protein potentiates bactericidal activity of human bactericidal/permeability-increasing protein by HORWITZ, A. H, WILLIAMS, R. E, NOWAKOWSKI, G

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Bactericidal/permeability-increasing protein inhibits growth of a strain of Acholeplasma laidlawii and L forms of the Gram-positive bacteria Staphylococcus aureus and Streptococcus pyogenes by HORWITZ, A. H, WILLIAMS, R. E, LIU, P.-S, NADELL, R

“…Bactericidal/permeability-increasing protein (BPI) inhibited growth of cell wall-deficient Acholeplasma laidlawii and L forms of certain strains of…”
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Potent Anti-CD5 Ricin A Chain Immunoconjugates from Bacterially Produced Fab' and F(ab') 2 by Better, Marc, Bernhard, Susan L., Lei, Shau-Ping, Fishwild, Dianne M., Lane, Julie A., Carroll, Stephen F., Howritz, Arnold H.

“…We have used genetic engineering to obtain secretion of anti-human CD5 antibody fragments from Escherichia coli for conjugation to the 30-kDa form of ricin A…”
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An amino-terminal fragment of human lipopolysaccharide-binding protein retains lipid A binding but not CD14-stimulatory activity by Theofan, G, Horwitz, AH, Williams, RE, Liu, PS, Chan, I, Birr, C, Carroll, SF, Meszaros, K, Parent, JB, Kasler, H

“…LPS-binding protein (LBP) mediates the pro-inflammatory effects of bacterial LPS by enhancing LPS-induced cytokine production by monocytic cells. LBP binds…”
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Human-engineered monoclonal antibodies retain full specific binding activity by preserving non-CDR complementarity-modulating residues by Studnicka, G M, Soares, S, Better, M, Williams, R E, Nadell, R, Horwitz, A H

“…Humanization of murine monoclonal antibodies for human therapy has commonly been achieved by complementarity-determining region (CDR) grafting, in which murine…”
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Chimeric immunoglobulin light chains are secreted at different levels: influence of framework-1 amino acids by Horwitz, A H, Nadell, R, Preugschat, F, Better, M

“…Immunoglobulin light chain proteins are generally thought to be readily secreted without their corresponding heavy chains; non-secreted light chains have been…”
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Expression of engineered antibodies and antibody fragments in microorganisms by Better, M, Horwitz, A H

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Deoxyribonucleic acid sequence of araBAD promoter mutants of Escherichia coli by Horwitz, A H, Morandi, C, Wilcox, G

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Biochemical characterization of recombinant fusions of lipopolysaccharide binding protein and bactericidal/permeability-increasing protein. Implications in biological activity by Abrahamson, S L, Wu, H M, Williams, R E, Der, K, Ottah, N, Little, R, Gazzano-Santoro, H, Theofan, G, Bauer, R, Leigh, S, Orme, A, Horwitz, A H, Carroll, S F, Dedrick, R L

“…The physiological response to endotoxin (lipopolysaccharide (LPS)) can be regulated by two closely related LPS-binding proteins, LPS-binding protein (LBP),…”
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Effects of magnesium, calcium, and serum on reversion of stable L-forms by Horwitz, A H, Casida, Jr, L E

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Functional limits of the araIc promoter suggest an additional regulatory site for araBAD expression by Horwitz, A H, Miyada, C G, Wilcox, G

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Characterization of a site-specific restriction endonuclease from Streptomyces aureofaciens by Timko, J, Horwitz, A H, Zelinka, J, Wilcox, G

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Survival and reversion of a stable L form in soil by Horwitz, A H, Casida, Jr, L E

“…The stable L form of Agromyces ramosus reverted to a bacterial form when incubated in sterilized soil. The cellular and colonial morphology of this bacterial…”
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The araIc mutation in Escherichia coli B/r by Cass, L G, Horwitz, A H, Wilcox, G

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Expression and Characterization of Cysteine-Modified Variants of an Amino-Terminal Fragment of Bactericidal/Permeability-Increasing Protein by Horwitz, Arnold H., Leigh, Scott D., Abrahamson, Susan, Gazzano-Santoro, Hélène, Liu, Pei-Syan, Williams, Robert E., Carroll, Stephen F., Theofan, Georgia

“…rBPI23is a biologically active, recombinant N-terminal fragment of human bactericidal/permeability-increasing protein (BPI). While rBPI23is readily purified…”
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Inclusion of S-sepharose beads in the culture medium significantly improves recovery of secreted rBPI(21) from transfected CHO-K1 cells by Horwitz, A H, Carroll, S F, Williams, R E, Liu, P S

“…rBPI(23), a recombinant N-terminal fragment of human bactericidal/permeability-increasing protein (BPI), kills gram-negative bacteria and binds endotoxin…”
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L-Phase variants of Agromyces ramosus by Horwitz, A H, Casida, Jr, L E

“…Agromyces ramosus, which is a numerically prevalent bacterium in soil, was easily induced into the L-phase by growing it on agar media containing low levels of…”
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