Search Results - "HORVATH, M"

Pivoting the Plant Immune System from Dissection to Deployment by Dangl, Jeffery L., Horvath, Diana M., Staskawicz, Brian J.

“…Diverse and rapidly evolving pathogens cause plant disease and epidemics that threaten crop yield and food security around the world. Research over the last 25…”
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The JAK-STAT pathway at 30: Much learned, much more to do by Philips, Rachael L., Wang, Yuxin, Cheon, HyeonJoo, Kanno, Yuka, Gadina, Massimo, Sartorelli, Vittorio, Horvath, Curt M., Darnell, James E., Stark, George R., O’Shea, John J.

“…The discovery of the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway arose from investigations of how cells respond to…”
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The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly by Bruns, Annie M., Leser, George P., Lamb, Robert A., Horvath, Curt M.

“…Cytoplasmic pattern recognition receptors detect non-self RNAs during virus infections and initiate antiviral signaling. One receptor, MDA5, possesses…”
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Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials by Greff, Dorina, Juhász, Anna E, Váncsa, Szilárd, Váradi, Alex, Sipos, Zoltán, Szinte, Julia, Park, Sunjune, Hegyi, Péter, Nyirády, Péter, Ács, Nándor, Várbíró, Szabolcs, Horváth, Eszter M

“…Metformin is the gold standard insulin sensitizer, which is widely used to treat insulin resistance in polycystic ovary syndrome (PCOS). However, metformin may…”
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RNA- and Virus-Independent Inhibition of Antiviral Signaling by RNA Helicase LGP2 by KOMURO, Akihiko, HORVATH, Curt M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An Evidence-Based Systematic Review of Human Knee Post-Traumatic Osteoarthritis (PTOA): Timeline of Clinical Presentation and Disease Markers, Comparison of Knee Joint PTOA Models and Early Disease Implications by Khella, Christine M, Asgarian, Rojiar, Horvath, Judith M, Rolauffs, Bernd, Hart, Melanie L

“…Understanding the causality of the post-traumatic osteoarthritis (PTOA) disease process of the knee joint is important for diagnosing early disease and…”
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Regulation of Signal Transduction by Enzymatically Inactive Antiviral RNA Helicase Proteins MDA5, RIG-I, and LGP2 by Bamming, Darja, Horvath, Curt M.

“…Intracellular pattern recognition receptors MDA5, RIG-I, and LGP2 are essential components of the cellular response to virus infection and are homologous to…”
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A Road Map for Those Who Don't Know JAK-STAT by Aaronson, David S., Horvath, Curt M.

“…The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway transmits information received from extracellular polypeptide signals,…”
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Upstream Stimulatory Factors Regulate HIV-1 Latency and Are Required for Robust T Cell Activation by Horvath, Riley M, Sadowski, Ivan

“…HIV-1 provirus expression is controlled by signaling pathways that are responsive to T cell receptor engagement, including those involving Ras and downstream…”
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Antiviral RNA recognition and assembly by RLR family innate immune sensors by Bruns, Annie M, Horvath, Curt M

“…Abstract Virus-encoded molecular signatures, such as cytosolic double-stranded or otherwise biochemically distinct RNA species, trigger cellular antiviral…”
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Inhibition of the TRIM24 bromodomain reactivates latent HIV-1 by Horvath, Riley M., Brumme, Zabrina L., Sadowski, Ivan

“…Expression of the HIV-1 genome by RNA Polymerase II is regulated at multiple steps, as are most cellular genes, including recruitment of general transcription…”
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STAT proteins and transcriptional responses to extracellular signals by Horvath, Curt M

“…Signal transducer and activator of transcription (STAT) transcription factors are implicated in programming gene expression in biological events as diverse as…”
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Influenza A Virus Infection of Human Respiratory Cells Induces Primary MicroRNA Expression by Buggele, William A., Johnson, Karen E., Horvath, Curt M.

“…The cellular response to virus infection is initiated by recognition of the invading pathogen and subsequent changes in gene expression mediated by both…”
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Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors by Tell, Robert W., Horvath, Curt M.

“…Signal transducer and activator of transcription 3 (STAT3), a latent transcription factor associated with inflammatory signaling and innate and adaptive immune…”
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Anti-Inflammatory Therapeutic Approaches to Prevent or Delay Post-Traumatic Osteoarthritis (PTOA) of the Knee Joint with a Focus on Sustained Delivery Approaches by Khella, Christine M, Horvath, Judith M, Asgarian, Rojiar, Rolauffs, Bernd, Hart, Melanie L

“…Inflammation plays a central role in the pathogenesis of knee PTOA after knee trauma. While a comprehensive therapy capable of preventing or delaying…”
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Isolation of MECP2-nuLl Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation by CHEUNG, Aaron Y. L, HORVATH, Lindsay M, GRAFODATSKAYA, Daria, PASCERI, Peter, WEKSBERG, Rosanna, HOTTA, Akitsu, CARREL, Laura, ELLIS, James

“…Rett syndrome (RTT) is a neurodevelopmental autism spectrum disorder that affects girls due primarily to mutations in the gene encoding methyl-CpG binding…”
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Naturally occurring allele diversity allows potato cultivation in northern latitudes by Kloosterman, Bjorn, Abelenda, José A., Gomez, María del Mar Carretero, Oortwijn, Marian, de Boer, Jan M., Kowitwanich, Krissana, Horvath, Beatrix M., van Eck, Herman J., Smaczniak, Cezary, Prat, Salomé, Visser, Richard G. F., Bachem, Christian W. B.

“…A genetic study of natural variation in potato tuberization onset, an important phenotype for breeding potatoes adapted to different global day lengths, has…”
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Interferon-Stimulated Transcription and Innate Antiviral Immunity Require Deacetylase Activity and Histone Deacetylase 1 by Nusinzon, Inna, Horvath, Curt M.

“…The use of histone deacetylase (HDAC) inhibitors has revealed an essential role for deacetylation in transcription of IFN-responsive genes. The HDAC1 protein…”
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A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory by Light, William H, Freaney, Jonathan, Sood, Varun, Thompson, Abbey, D'Urso, Agustina, Horvath, Curt M, Brickner, Jason H

“…The interaction of nuclear pore proteins (Nups) with active genes can promote their transcription. In yeast, some inducible genes interact with the nuclear…”
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Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control by Horvath, Beatrix M, Kourova, Hana, Nagy, Szilvia, Nemeth, Edit, Magyar, Zoltan, Papdi, Csaba, Ahmad, Zaki, Sanchez‐Perez, Gabino F, Perilli, Serena, Blilou, Ikram, Pettkó‐Szandtner, Aladár, Darula, Zsuzsanna, Meszaros, Tamas, Binarova, Pavla, Bogre, Laszlo, Scheres, Ben

“…The rapidly proliferating cells in plant meristems must be protected from genome damage. Here, we show that the regulatory role of the Arabidopsis…”
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